ID   RRT5_VANPO              Reviewed;         333 AA.
AC   A7TQR2;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Regulator of rDNA transcription protein 5;
GN   Name=RRT5; ORFNames=Kpol_1063p18;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: May be involved in the modulation of rDNA transcription.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRT5 family. {ECO:0000305}.
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DR   EMBL; DS480462; EDO15407.1; -; Genomic_DNA.
DR   RefSeq; XP_001643265.1; XM_001643215.1.
DR   AlphaFoldDB; A7TQR2; -.
DR   STRING; 436907.A7TQR2; -.
DR   EnsemblFungi; EDO15407; EDO15407; Kpol_1063p18.
DR   GeneID; 5543482; -.
DR   KEGG; vpo:Kpol_1063p18; -.
DR   eggNOG; ENOG502RZDM; Eukaryota.
DR   HOGENOM; CLU_042558_0_0_1; -.
DR   InParanoid; A7TQR2; -.
DR   OMA; IWIFRTR; -.
DR   OrthoDB; 1442049at2759; -.
DR   PhylomeDB; A7TQR2; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12409; RRM1_RRT5; 1.
DR   CDD; cd12410; RRM2_RRT5; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR034244; Rrt5_RRM1.
DR   InterPro; IPR034247; Rrt5_RRM2.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; RNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..333
FT                   /note="Regulator of rDNA transcription protein 5"
FT                   /id="PRO_0000404360"
FT   DOMAIN          31..114
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          182..267
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          123..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          281..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..179
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        281..296
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        311..333
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   333 AA;  36876 MW;  42126558DFC477E6 CRC64;
     MFERQSNNPE PIEVSDNNPE RESTADALLT TRIYISNLDY SSTEDELIEY LKDYKPLSVL
     VPSHTVRGFR SNHVKPLGIA YADFETPEKA REAVEALNET NFKNRNLKVK LYVPFSPENV
     CKPAPKPRRL SKLRRSKKPA DEENNAASQD PTVEATQERG QASEDPENAA NNAKQAKPTS
     DDTVYCGYLP KNTTDADLRE HFKDYNPQEI WIFRTRAAKG PMHLQLHRHY TAALITLNSP
     ETIAKIAEVT STKKILGKKI SVKPAYISKI QEVKKIAEQT GIAERNQTNK GAIKPNSGNG
     GQPAGPGVAG EPSNPQQNCD NSNNVQPGVS VVA