RS10B_MOUSE
ID RS10B_MOUSE Reviewed; 876 AA.
AC E9PYQ0;
DT 22-APR-2020, integrated into UniProtKB/Swiss-Prot.
DT 05-APR-2011, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Radial spoke head 10 homolog B {ECO:0000305};
GN Name=Rsph10b {ECO:0000312|MGI:MGI:1922386};
GN Synonyms=Rsph10b2 {ECO:0000312|MGI:MGI:1922386};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000312|Ensembl:ENSMUSP00000132687, ECO:0000312|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP INTERACTION WITH RSPH6A.
RX PubMed=30185526; DOI=10.1242/jcs.221648;
RA Abbasi F., Miyata H., Shimada K., Morohoshi A., Nozawa K., Matsumura T.,
RA Xu Z., Pratiwi P., Ikawa M.;
RT "RSPH6A is required for sperm flagellum formation and male fertility in
RT mice.";
RL J. Cell Sci. 131:0-0(2018).
CC -!- SUBUNIT: Interacts with RSPH6A. {ECO:0000269|PubMed:30185526}.
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DR EMBL; AC121917; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; E9PYQ0; -.
DR SMR; E9PYQ0; -.
DR STRING; 10090.ENSMUSP00000132687; -.
DR iPTMnet; E9PYQ0; -.
DR PhosphoSitePlus; E9PYQ0; -.
DR PaxDb; E9PYQ0; -.
DR PRIDE; E9PYQ0; -.
DR ProteomicsDB; 313990; -.
DR Ensembl; ENSMUST00000166847; ENSMUSP00000132687; ENSMUSG00000075569.
DR MGI; MGI:1922386; Rsph10b.
DR VEuPathDB; HostDB:ENSMUSG00000075569; -.
DR eggNOG; KOG0231; Eukaryota.
DR GeneTree; ENSGT00940000159899; -.
DR HOGENOM; CLU_012108_1_0_1; -.
DR InParanoid; E9PYQ0; -.
DR OMA; IHPNACH; -.
DR PhylomeDB; E9PYQ0; -.
DR TreeFam; TF328649; -.
DR PRO; PR:E9PYQ0; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; E9PYQ0; protein.
DR Bgee; ENSMUSG00000075569; Expressed in lens of camera-type eye and 86 other tissues.
DR ExpressionAtlas; E9PYQ0; baseline and differential.
DR InterPro; IPR003409; MORN.
DR Pfam; PF02493; MORN; 10.
DR SMART; SM00698; MORN; 9.
PE 1: Evidence at protein level;
KW Coiled coil; Reference proteome; Repeat.
FT CHAIN 1..876
FT /note="Radial spoke head 10 homolog B"
FT /id="PRO_0000449425"
FT REPEAT 86..108
FT /note="MORN 1"
FT /evidence="ECO:0000255"
FT REPEAT 109..129
FT /note="MORN 2"
FT /evidence="ECO:0000255"
FT REPEAT 132..154
FT /note="MORN 3"
FT /evidence="ECO:0000255"
FT REPEAT 155..172
FT /note="MORN 4"
FT /evidence="ECO:0000255"
FT REPEAT 179..196
FT /note="MORN 5"
FT /evidence="ECO:0000255"
FT REPEAT 204..225
FT /note="MORN 6"
FT /evidence="ECO:0000255"
FT REPEAT 227..244
FT /note="MORN 7"
FT /evidence="ECO:0000255"
FT REPEAT 251..268
FT /note="MORN 8"
FT /evidence="ECO:0000255"
FT REPEAT 284..305
FT /note="MORN 9"
FT /evidence="ECO:0000255"
FT REPEAT 307..328
FT /note="MORN 10"
FT /evidence="ECO:0000255"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 839..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 790..832
FT /evidence="ECO:0000255"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 876 AA; 101575 MW; 1BF00A2ABA129688 CRC64;
MVKEKKKADK KGDKSARSPS SISDNPEASK QDSNASKQEV APSAVVPVVE TPLKQAPKRD
SVQMEQSEEE TQYEEPILTK LIVESYEGEK VRGLYEGEGF AVFQGGNTYH GMFSEGLMHG
QGTYIWADGL KYEGDFVKNI PMNHGVYTWP DGSTYEGEVT NGMRNGFGMF KCGTQPVSYI
GHWCHGKRHG KGSIYYNQEG TSWYEGDWVY NIKKGWGIRC YKSGNIYEGQ WENNMRHGEG
RMRWLTTNEE YTGHWEKGIQ NGFGTHTWFL KRIPNSQYPL RNEYIGEFVN GFRHGQGKFY
YASGAMYEGE WASNKKQGRG RMTFKNGHVY EGLFSNDHIA QFFETEMDYS QSLDRWSDAS
QRSRQPRGSS VSAVREPETL RKLDGSESRS VLGTSIELDL TLLLDMYPEE SQEEEKKQVE
YAVLRNITEL RRIYCFYSGL GCDHSLDNTF LMTKLHFWRF LKDCRFHHHN ITLADMDRVL
SVYNGIPIEE IHSPFRTILL RTFLNYLLQL AYYIHHKEFQ NRSPSLFLCF TKLMSENIHP
HACQVKGHLF SEQQRTLYSM NYIDKCWEIY TAYCRPNEAP PYELTMKMRY FLWMLKDFRM
INKDLTATKF MTVIAEDNPF VYDGTDSNFE LELVFLEFFE ALLCFSLCCM FDQMTRSYLK
VPYDDITTNR YGSTQTILNQ SIHRSPSAIT SHDSEVHFSS TKSSLDKIGA LPDGKIRQSE
PKLKKSLSED KVSKMNFKTQ GRGLVFMSPQ GEKYEKPKDE QKEKLNIWVN NLYVFFVSVL
FSAYKREEML KEKVKENQLQ EAELAQQRQI ENEELEARLN ILREEEARKQ DFELDITVLK
EPSEIPASQP LTPSPPKEDL ASIQTSKASP GKKKKK
