RS12A_SCHPO
ID RS12A_SCHPO Reviewed; 145 AA.
AC O14062;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=40S ribosomal protein S12-A;
GN Name=rps1201; Synonyms=rps12, rps12a; ORFNames=SPCC962.04;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- MISCELLANEOUS: There are two genes for S12 in S.pombe.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS12 family.
CC {ECO:0000305}.
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DR EMBL; CU329672; CAA20436.1; -; Genomic_DNA.
DR PIR; T41651; T41651.
DR RefSeq; NP_587869.1; NM_001022861.2.
DR AlphaFoldDB; O14062; -.
DR SMR; O14062; -.
DR BioGRID; 276146; 31.
DR STRING; 4896.SPCC962.04.1; -.
DR iPTMnet; O14062; -.
DR MaxQB; O14062; -.
DR PaxDb; O14062; -.
DR PRIDE; O14062; -.
DR EnsemblFungi; SPCC962.04.1; SPCC962.04.1:pep; SPCC962.04.
DR GeneID; 2539588; -.
DR KEGG; spo:SPCC962.04; -.
DR PomBase; SPCC962.04; rps1201.
DR VEuPathDB; FungiDB:SPCC962.04; -.
DR eggNOG; KOG3406; Eukaryota.
DR HOGENOM; CLU_110343_1_1_1; -.
DR InParanoid; O14062; -.
DR OMA; DLGQWVG; -.
DR PhylomeDB; O14062; -.
DR Reactome; R-SPO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-SPO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-SPO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-SPO-72649; Translation initiation complex formation.
DR Reactome; R-SPO-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-SPO-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR Reactome; R-SPO-72702; Ribosomal scanning and start codon recognition.
DR Reactome; R-SPO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-SPO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-SPO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:O14062; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; ISO:PomBase.
DR GO; GO:0003735; F:structural constituent of ribosome; ISO:PomBase.
DR GO; GO:0002181; P:cytoplasmic translation; ISO:PomBase.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR029064; L30e-like.
DR InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR InterPro; IPR000530; Ribosomal_S12e.
DR PANTHER; PTHR11843; PTHR11843; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00972; RIBSOMALS12E.
DR SUPFAM; SSF55315; SSF55315; 1.
DR PROSITE; PS01189; RIBOSOMAL_S12E; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..145
FT /note="40S ribosomal protein S12-A"
FT /id="PRO_0000122338"
SQ SEQUENCE 145 AA; 15616 MW; 5311DFAA1672FEA0 CRC64;
MSEQGDQIEQ VDVVEEVEVE AAAPETVSVE DALKEVLKRA LVHDGLARGI REASKALDRR
QAHLCVLCES CDQEAYVKLV EALCAESETP LIKVADPKVL GEWAGLCVLD RDGNARKVVG
CSCVAVTDYG EDSAALQKLL ESFSA