RS12_ACIB5
ID RS12_ACIB5 Reviewed; 124 AA.
AC B7I7R9;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=30S ribosomal protein S12 {ECO:0000255|HAMAP-Rule:MF_00403};
GN Name=rpsL {ECO:0000255|HAMAP-Rule:MF_00403}; OrderedLocusNames=AB57_0911;
OS Acinetobacter baumannii (strain AB0057).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=480119;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AB0057;
RX PubMed=18931120; DOI=10.1128/jb.00834-08;
RA Adams M.D., Goglin K., Molyneaux N., Hujer K.M., Lavender H., Jamison J.J.,
RA MacDonald I.J., Martin K.M., Russo T., Campagnari A.A., Hujer A.M.,
RA Bonomo R.A., Gill S.R.;
RT "Comparative genome sequence analysis of multidrug-resistant Acinetobacter
RT baumannii.";
RL J. Bacteriol. 190:8053-8064(2008).
CC -!- FUNCTION: With S4 and S5 plays an important role in translational
CC accuracy. {ECO:0000255|HAMAP-Rule:MF_00403}.
CC -!- FUNCTION: Interacts with and stabilizes bases of the 16S rRNA that are
CC involved in tRNA selection in the A site and with the mRNA backbone.
CC Located at the interface of the 30S and 50S subunits, it traverses the
CC body of the 30S subunit contacting proteins on the other side and
CC probably holding the rRNA structure together. The combined cluster of
CC proteins S8, S12 and S17 appears to hold together the shoulder and
CC platform of the 30S subunit. {ECO:0000255|HAMAP-Rule:MF_00403}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts proteins S8 and
CC S17. May interact with IF1 in the 30S initiation complex.
CC {ECO:0000255|HAMAP-Rule:MF_00403}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS12 family.
CC {ECO:0000255|HAMAP-Rule:MF_00403}.
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DR EMBL; CP001182; ACJ40703.1; -; Genomic_DNA.
DR RefSeq; WP_000246374.1; NC_011586.2.
DR PDB; 6V39; EM; 3.04 A; l=1-124.
DR PDB; 6V3A; EM; 2.82 A; l=1-124.
DR PDB; 6V3B; EM; 2.91 A; l=1-124.
DR PDB; 6V3E; EM; 4.40 A; l=1-124.
DR PDB; 7M4U; EM; 2.71 A; l=1-124.
DR PDB; 7M4W; EM; 2.55 A; l=1-124.
DR PDB; 7M4X; EM; 2.66 A; l=1-124.
DR PDB; 7M4Y; EM; 2.50 A; l=1-124.
DR PDB; 7M4Z; EM; 2.92 A; l=1-124.
DR PDB; 7RYF; EM; 2.65 A; l=1-124.
DR PDB; 7RYG; EM; 2.38 A; l=1-124.
DR PDB; 7RYH; EM; 2.43 A; l=1-124.
DR PDBsum; 6V39; -.
DR PDBsum; 6V3A; -.
DR PDBsum; 6V3B; -.
DR PDBsum; 6V3E; -.
DR PDBsum; 7M4U; -.
DR PDBsum; 7M4W; -.
DR PDBsum; 7M4X; -.
DR PDBsum; 7M4Y; -.
DR PDBsum; 7M4Z; -.
DR PDBsum; 7RYF; -.
DR PDBsum; 7RYG; -.
DR PDBsum; 7RYH; -.
DR AlphaFoldDB; B7I7R9; -.
DR SMR; B7I7R9; -.
DR IntAct; B7I7R9; 1.
DR GeneID; 64223788; -.
DR GeneID; 66398193; -.
DR KEGG; abn:AB57_0911; -.
DR HOGENOM; CLU_104295_1_2_6; -.
DR OMA; SPALEKC; -.
DR Proteomes; UP000007094; Chromosome.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd03368; Ribosomal_S12; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR HAMAP; MF_00403_B; Ribosomal_S12_B; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR006032; Ribosomal_S12/S23.
DR InterPro; IPR005679; Ribosomal_S12_bac.
DR PANTHER; PTHR11652; PTHR11652; 1.
DR Pfam; PF00164; Ribosom_S12_S23; 1.
DR PIRSF; PIRSF002133; Ribosomal_S12/S23; 1.
DR PRINTS; PR01034; RIBOSOMALS12.
DR SUPFAM; SSF50249; SSF50249; 1.
DR TIGRFAMs; TIGR00981; rpsL_bact; 1.
DR PROSITE; PS00055; RIBOSOMAL_S12; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Methylation; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; tRNA-binding.
FT CHAIN 1..124
FT /note="30S ribosomal protein S12"
FT /id="PRO_1000194103"
FT MOD_RES 89
FT /note="3-methylthioaspartic acid"
FT /evidence="ECO:0000250"
FT HELIX 4..9
FT /evidence="ECO:0007829|PDB:7M4U"
FT STRAND 28..40
FT /evidence="ECO:0007829|PDB:7M4U"
FT STRAND 50..57
FT /evidence="ECO:0007829|PDB:7M4U"
FT STRAND 62..66
FT /evidence="ECO:0007829|PDB:7M4U"
FT STRAND 79..84
FT /evidence="ECO:0007829|PDB:7M4U"
FT STRAND 88..90
FT /evidence="ECO:0007829|PDB:7M4U"
FT STRAND 95..97
FT /evidence="ECO:0007829|PDB:7M4U"
FT STRAND 101..104
FT /evidence="ECO:0007829|PDB:7M4U"
FT TURN 115..118
FT /evidence="ECO:0007829|PDB:7M4U"
SQ SEQUENCE 124 AA; 13766 MW; 9D80FAA9B2238345 CRC64;
MATTNQLIRK GRTTLVEKSK VPALKACPQR RGVCTRVYTT TPKKPNSAMR KVCRVRLTSG
FEVSSYIGGE GHNLQEHSVV LIRGGRVKDL PGVRYHTVRG SLDCAGVKDR NQSRSKYGAK
RPKK
