ID   RS12_DICDI              Reviewed;         136 AA.
AC   Q54PX9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=40S ribosomal protein S12;
GN   Name=rps12; ORFNames=DDB_G0284237;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=AX2;
RX   PubMed=16926386; DOI=10.1074/mcp.m600113-mcp200;
RA   Gotthardt D., Blancheteau V., Bosserhoff A., Ruppert T., Delorenzi M.,
RA   Soldati T.;
RT   "Proteomics fingerprinting of phagosome maturation and evidence for the
RT   role of a Galpha during uptake.";
RL   Mol. Cell. Proteomics 5:2228-2243(2006).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS12 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000064; EAL65307.1; -; Genomic_DNA.
DR   RefSeq; XP_638666.1; XM_633574.1.
DR   AlphaFoldDB; Q54PX9; -.
DR   SMR; Q54PX9; -.
DR   STRING; 44689.DDB0230044; -.
DR   PaxDb; Q54PX9; -.
DR   EnsemblProtists; EAL65307; EAL65307; DDB_G0284237.
DR   GeneID; 8624495; -.
DR   KEGG; ddi:DDB_G0284237; -.
DR   dictyBase; DDB_G0284237; rps12.
DR   eggNOG; KOG3406; Eukaryota.
DR   HOGENOM; CLU_110343_1_0_1; -.
DR   InParanoid; Q54PX9; -.
DR   OMA; CDEPMYK; -.
DR   PhylomeDB; Q54PX9; -.
DR   Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DDI-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DDI-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-DDI-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q54PX9; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0031012; C:extracellular matrix; HDA:dictyBase.
DR   GO; GO:0045335; C:phagocytic vesicle; HDA:dictyBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0009617; P:response to bacterium; HEP:dictyBase.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR   InterPro; IPR000530; Ribosomal_S12e.
DR   PANTHER; PTHR11843; PTHR11843; 1.
DR   Pfam; PF01248; Ribosomal_L7Ae; 1.
DR   PRINTS; PR00972; RIBSOMALS12E.
DR   SUPFAM; SSF55315; SSF55315; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..136
FT                   /note="40S ribosomal protein S12"
FT                   /id="PRO_0000319987"
SQ   SEQUENCE   136 AA;  14906 MW;  CF8460162991E595 CRC64;
     MEGDAPVIAA NPLEKNTDPM VALQKVIKES LAVQGVARGL HETVKALDKR TARLCVLASN
     CDEPNFVRLV KALATEHNIP LIEVPDNKAL GEWAGLCKLD KDLAARKVVA CSTLVIKTFG
     KESDDYKFLM EYISKQ