ID   RS12_PIG                Reviewed;         132 AA.
AC   P46405;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=40S ribosomal protein S12;
GN   Name=RPS12;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Brain;
RX   PubMed=7622064; DOI=10.1016/0378-1119(95)00067-g;
RA   Zach O.R.F., Bauer H.C., Richter K., Webersinke G., Bauer H.;
RT   "Sequence of the porcine full-length cDNA encoding ribosomal protein
RT   rpS12.";
RL   Gene 159:277-278(1995).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS12 family.
CC       {ECO:0000305}.
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DR   EMBL; X79417; CAA55946.1; -; mRNA.
DR   PIR; JC4159; JC4159.
DR   RefSeq; NP_999528.1; NM_214363.1.
DR   PDB; 3J7R; EM; 3.90 A; SM=9-132.
DR   PDBsum; 3J7R; -.
DR   AlphaFoldDB; P46405; -.
DR   SMR; P46405; -.
DR   STRING; 9823.ENSSSCP00000004510; -.
DR   PaxDb; P46405; -.
DR   PeptideAtlas; P46405; -.
DR   PRIDE; P46405; -.
DR   Ensembl; ENSSSCT00000004616; ENSSSCP00000004510; ENSSSCG00000004177.
DR   Ensembl; ENSSSCT00005061568; ENSSSCP00005038064; ENSSSCG00005038483.
DR   Ensembl; ENSSSCT00005061587; ENSSSCP00005038080; ENSSSCG00005038483.
DR   Ensembl; ENSSSCT00015100251; ENSSSCP00015041457; ENSSSCG00015074513.
DR   Ensembl; ENSSSCT00025003879; ENSSSCP00025001497; ENSSSCG00025002953.
DR   Ensembl; ENSSSCT00030050781; ENSSSCP00030023085; ENSSSCG00030036524.
DR   Ensembl; ENSSSCT00035047803; ENSSSCP00035019127; ENSSSCG00035036063.
DR   Ensembl; ENSSSCT00040088968; ENSSSCP00040039106; ENSSSCG00040065172.
DR   Ensembl; ENSSSCT00045044973; ENSSSCP00045031201; ENSSSCG00045026421.
DR   Ensembl; ENSSSCT00050024929; ENSSSCP00050010408; ENSSSCG00050018386.
DR   Ensembl; ENSSSCT00055034686; ENSSSCP00055027544; ENSSSCG00055017713.
DR   Ensembl; ENSSSCT00055034802; ENSSSCP00055027641; ENSSSCG00055017713.
DR   Ensembl; ENSSSCT00060098537; ENSSSCP00060042736; ENSSSCG00060072109.
DR   Ensembl; ENSSSCT00065046991; ENSSSCP00065020214; ENSSSCG00065034515.
DR   Ensembl; ENSSSCT00065047000; ENSSSCP00065020218; ENSSSCG00065034515.
DR   Ensembl; ENSSSCT00070044762; ENSSSCP00070037723; ENSSSCG00070022487.
DR   Ensembl; ENSSSCT00070044769; ENSSSCP00070037728; ENSSSCG00070022487.
DR   GeneID; 397650; -.
DR   KEGG; ssc:397650; -.
DR   CTD; 6206; -.
DR   VGNC; VGNC:103165; RPS12.
DR   eggNOG; KOG3406; Eukaryota.
DR   GeneTree; ENSGT00390000018318; -.
DR   HOGENOM; CLU_110343_1_1_1; -.
DR   InParanoid; P46405; -.
DR   OMA; CDEPMYK; -.
DR   OrthoDB; 1474866at2759; -.
DR   TreeFam; TF300196; -.
DR   Reactome; R-SSC-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-SSC-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-SSC-72649; Translation initiation complex formation.
DR   Reactome; R-SSC-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-SSC-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-SSC-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-SSC-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   ChiTaRS; RPS12; pig.
DR   Proteomes; UP000008227; Chromosome 1.
DR   Proteomes; UP000314985; Chromosome 1.
DR   Bgee; ENSSSCG00000004177; Expressed in forelimb bud and 43 other tissues.
DR   ExpressionAtlas; P46405; baseline and differential.
DR   Genevisible; P46405; SS.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR   InterPro; IPR000530; Ribosomal_S12e.
DR   PANTHER; PTHR11843; PTHR11843; 1.
DR   Pfam; PF01248; Ribosomal_L7Ae; 1.
DR   PRINTS; PR00972; RIBSOMALS12E.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   PROSITE; PS01189; RIBOSOMAL_S12E; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acetylation; Cytoplasm; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:P25398"
FT   CHAIN           2..132
FT                   /note="40S ribosomal protein S12"
FT                   /id="PRO_0000122325"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:P25398"
FT   MOD_RES         129
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P63323"
SQ   SEQUENCE   132 AA;  14515 MW;  45AD1274D55FFA25 CRC64;
     MAEEGIAAGG VMDVNTALQE VLKTALIHDG LARGIREAAK ALDKRQAHLC VLASNCDEPM
     YVKLVEALCA EHQINLIKVD DNKKLGEWVG LCKIDREGKP RKVVGCSCVV VKDYGKESQA
     KDVIEEYFKC KK