ID   ABAA_PENRW              Reviewed;         795 AA.
AC   B6H7F3;
DT   13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Conidiophore development regulator abaA {ECO:0000305};
GN   Name=abaA {ECO:0000303|PubMed:21148688}; ORFNames=Pc16g09610;
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255;
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
RN   [2]
RP   INDUCTION.
RX   PubMed=21148688; DOI=10.1128/aem.01557-10;
RA   Sigl C., Haas H., Specht T., Pfaller K., Kuernsteiner H., Zadra I.;
RT   "Among developmental regulators, StuA but not BrlA is essential for
RT   penicillin V production in Penicillium chrysogenum.";
RL   Appl. Environ. Microbiol. 77:972-982(2011).
CC   -!- FUNCTION: BrlA, abaA and wetA are pivotal regulators of conidiophore
CC       development and conidium maturation (By similarity). They act
CC       individually and together to regulate their own expression and that of
CC       numerous other sporulation-specific genes (By similarity). Binds to the
CC       sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and
CC       minor-groove contacts (By similarity). {ECO:0000250|UniProtKB:P20945}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:I1S4T3}.
CC       Note=localizes to the nuclei of phialides and terminal cells of mature
CC       conidia (By similarity). {ECO:0000250|UniProtKB:I1S4T3}.
CC   -!- INDUCTION: Expression is also positively regulated by stuA
CC       (PubMed:21148688). {ECO:0000269|PubMed:21148688}.
CC   -!- SIMILARITY: Belongs to the TEC1 family. {ECO:0000305}.
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DR   EMBL; AM920431; CAP93631.1; -; Genomic_DNA.
DR   RefSeq; XP_002561273.1; XM_002561227.1.
DR   AlphaFoldDB; B6H7F3; -.
DR   SMR; B6H7F3; -.
DR   STRING; 1108849.XP_002561273.1; -.
DR   PRIDE; B6H7F3; -.
DR   EnsemblFungi; CAP93631; CAP93631; PCH_Pc16g09610.
DR   GeneID; 8314104; -.
DR   KEGG; pcs:Pc16g09610; -.
DR   VEuPathDB; FungiDB:PCH_Pc16g09610; -.
DR   eggNOG; KOG3841; Eukaryota.
DR   HOGENOM; CLU_356362_0_0_1; -.
DR   OMA; MWVSAPQ; -.
DR   OrthoDB; 258258at2759; -.
DR   BioCyc; PCHR:PC16G09610-MON; -.
DR   Proteomes; UP000000724; Contig Pc00c16.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048315; P:conidium formation; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 6.10.20.40; -; 1.
DR   InterPro; IPR000818; TEA/ATTS_dom.
DR   InterPro; IPR038096; TEA/ATTS_sf.
DR   Pfam; PF01285; TEA; 1.
DR   PRINTS; PR00065; TEADOMAIN.
DR   SMART; SM00426; TEA; 1.
DR   PROSITE; PS00554; TEA_1; 1.
DR   PROSITE; PS51088; TEA_2; 1.
PE   2: Evidence at transcript level;
KW   Activator; Conidiation; Nucleus; Reference proteome; Sporulation;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..795
FT                   /note="Conidiophore development regulator abaA"
FT                   /id="PRO_0000435937"
FT   DNA_BIND        128..202
FT                   /note="TEA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00505"
FT   REGION          61..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          210..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          528..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          769..795
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..110
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  88428 MW;  9705DC77E2363DFC CRC64;
     MATDWQPECL VTQNQTSLDP VGAHSDRALQ NTTGNVQSYS DQLAHADITA REDQLHQLGF
     KYPHAPHHPQ PLSAPGLHQQ HVAARLHQRK LRRLHSVGPN SQSRRARSSY LKSQKYLEYR
     ARPRRDTGKD GEPVWSDELE DAFQQALEAN PPMGRRKWSE RGKSYGRNEL IAEYIFKLTG
     KRRTRKQVSS HLQVLDSFLK GDPDWERLVR EASPERSSSV HGSAPAPKWR TAMEHPSASS
     HYGSHTHPSY HDHMRSMQPY AGDLPPPHYP LGSNMQEAAA SAIHGFSFDM WVSAPQQANR
     LDKALHAYTR LQGDLHHPVA PPMPLEHVSG WRSSFPQLAS MVDDINNPLD CDIILLEVNL
     ELMTDFPPAG SRLGIQLDLD YGHPTAGDVL GVSQMDNWTC STHIYEDSQK ILETYHDLPK
     TQSTKVKPLF ESSWWAKLFT QLTQEKRMAE DSGNPQAARD ADDHARHFFR SLSAVQELRA
     TPPSSRRLST QYQGHHGDES KRMAILAWKF RQTRPGEVGT TTWRRLIPAP DRTTTNSPRP
     VSGVDRPPLS LDSILLNKPS HQGVYQTPQP HDLIHHPSQS HSQWPMYQSP HDNVANLFNT
     PGHLDFMTSI SKAEDGLNDK TAVTSVLDSF STSLAPESIP STSLHGPSGA PVMLNVHDLP
     LSHPGMGYTM GHEASHYVPS QQHSVNMHDS NSVLHGFFGS NTQPLDDLSH GQASWGAHST
     SIPGDVGAGS YQLPYQPEHH VPVSRESQQP HHFDGLLPSE DLMDKIVGRM SNGPSIHGAG
     PDASAGYDNA TVDAV