ID   ABAB_STRAT              Reviewed;         301 AA.
AC   P52659;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=HTH-type transcriptional regulator AbaB {ECO:0000305|PubMed:9037760};
GN   Name=abaB {ECO:0000303|PubMed:9037760};
OS   Streptomyces antibioticus.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1890;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PUTATIVE FUNCTION.
RC   STRAIN=ATCC 11891 / DSM 40868 / BCRC 11580 / NCIMB 11506 / PSA 205;
RX   PubMed=9037760; DOI=10.1111/j.1574-6968.1997.tb10216.x;
RA   Scheu A.K., Martinez E., Soliveri J., Malpartida F.;
RT   "abaB, a putative regulator for secondary metabolism in Streptomyces.";
RL   FEMS Microbiol. Lett. 147:29-36(1997).
CC   -!- FUNCTION: Putative regulator that may be involved in stimulating
CC       antibiotic production in S.antibioticus. {ECO:0000305|PubMed:9037760}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; X91393; CAA62739.1; -; Genomic_DNA.
DR   AlphaFoldDB; P52659; -.
DR   SMR; P52659; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..301
FT                   /note="HTH-type transcriptional regulator AbaB"
FT                   /id="PRO_0000105592"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   301 AA;  32097 MW;  457AEA903A652000 CRC64;
     MDLALLRTFV TVHRAGSFTR AAALLGLSQP AVTSQIRTLE RQLGRPLFLR QARGVTPTTI
     GDELAHRAAP HLDALVEIAE SGLDDDSSSR TLYLAGPPEF TTERVLPALT GLTGDDGQGL
     TLRVSFGTAE ETLEGLSCGR HDLAISTTRP RGALLSATPL CDEEHVLVAA PRWAERIGAD
     TVRLKGAPAL DDLPVVEVHE SLPFVSRYWA SVFDCAPAAT GTVIVPDLRA VLSCASAGAG
     LAVLPRYLCA RALEQGAVVT LLDPVVPPLR TYFLVVRTGT LALPHVARAH EWLRHAATAW
     C