RS15A_HUMAN
ID RS15A_HUMAN Reviewed; 130 AA.
AC P62244; P39027; P39031; Q3MHD9; Q8C023; Q9BV24;
DT 05-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 180.
DE RecName: Full=40S ribosomal protein S15a;
DE AltName: Full=Small ribosomal subunit protein uS8 {ECO:0000303|PubMed:24524803};
GN Name=RPS15A; ORFNames=OK/SW-cl.82;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Schwabe G.;
RL Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Carcinoma;
RA Mays G., Burchert-Graeve M.;
RL Submitted (FEB-1995) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Lian Z., Liu J., Li L., Li X., Tufan S.N.L., Wu M.-C., Wang H.,
RA Arbuthnot P., Kew M.K., Feitelson M.M.;
RT "Human S15a expression is up-regulated by HBV X protein.";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Colon adenocarcinoma;
RA Shichijo S., Itoh K.;
RT "Identification of immuno-peptidmics that are recognized by tumor-reactive
RT CTL generated from TIL of colon cancer patients.";
RL Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye, Lung, and Skin;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [6]
RP PROTEIN SEQUENCE OF 2-17 AND 33-60.
RC TISSUE=Placenta;
RX PubMed=8706699; DOI=10.1111/j.1432-1033.1996.0144u.x;
RA Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K., Egorov T.A.,
RA Thiede B., Wittmann-Liebold B., Otto A.;
RT "Characterization of the human small-ribosomal-subunit proteins by N-
RT terminal and internal sequencing, and mass spectrometry.";
RL Eur. J. Biochem. 239:144-149(1996).
RN [7]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 46-54.
RX PubMed=9582194; DOI=10.1101/gr.8.5.509;
RA Kenmochi N., Kawaguchi T., Rozen S., Davis E., Goodman N., Hudson T.J.,
RA Tanaka T., Page D.C.;
RT "A map of 75 human ribosomal protein genes.";
RL Genome Res. 8:509-523(1998).
RN [8]
RP PARTIAL PROTEIN SEQUENCE.
RX PubMed=8185605; DOI=10.1006/bbrc.1994.1620;
RA Chan Y.-L., Olvera J., Paz V., Wool I.G.;
RT "The primary structure of rat ribosomal protein S15a.";
RL Biochem. Biophys. Res. Commun. 200:1498-1504(1994).
RN [9]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC TISSUE=Lymphoblast;
RX PubMed=14654843; DOI=10.1038/nature02166;
RA Andersen J.S., Wilkinson C.J., Mayor T., Mortensen P., Nigg E.A., Mann M.;
RT "Proteomic characterization of the human centrosome by protein correlation
RT profiling.";
RL Nature 426:570-574(2003).
RN [10]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [11]
RP NOMENCLATURE.
RX PubMed=24524803; DOI=10.1016/j.sbi.2014.01.002;
RA Ban N., Beckmann R., Cate J.H.D., Dinman J.D., Dragon F., Ellis S.R.,
RA Lafontaine D.L.J., Lindahl L., Liljas A., Lipton J.M., McAlear M.A.,
RA Moore P.B., Noller H.F., Ortega J., Panse V.G., Ramakrishnan V.,
RA Spahn C.M.T., Steitz T.A., Tchorzewski M., Tollervey D., Warren A.J.,
RA Williamson J.R., Wilson D., Yonath A., Yusupov M.;
RT "A new system for naming ribosomal proteins.";
RL Curr. Opin. Struct. Biol. 24:165-169(2014).
RN [12]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=25944712; DOI=10.1002/pmic.201400617;
RA Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D.,
RA Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT "N-terminome analysis of the human mitochondrial proteome.";
RL Proteomics 15:2519-2524(2015).
RN [13]
RP INVOLVEMENT IN DBA20, AND FUNCTION.
RX PubMed=27909223; DOI=10.3324/haematol.2016.153932;
RA Ikeda F., Yoshida K., Toki T., Uechi T., Ishida S., Nakajima Y.,
RA Sasahara Y., Okuno Y., Kanezaki R., Terui K., Kamio T., Kobayashi A.,
RA Fujita T., Sato-Otsubo A., Shiraishi Y., Tanaka H., Chiba K., Muramatsu H.,
RA Kanno H., Ohga S., Ohara A., Kojima S., Kenmochi N., Miyano S., Ogawa S.,
RA Ito E.;
RT "Exome sequencing identified RPS15A as a novel causative gene for Diamond-
RT Blackfan anemia.";
RL Haematologica 102:E93-E96(2017).
RN [14]
RP STRUCTURE BY ELECTRON MICROSCOPY (5.0 ANGSTROMS), SUBUNIT, AND FUNCTION.
RX PubMed=23636399; DOI=10.1038/nature12104;
RA Anger A.M., Armache J.P., Berninghausen O., Habeck M., Subklewe M.,
RA Wilson D.N., Beckmann R.;
RT "Structures of the human and Drosophila 80S ribosome.";
RL Nature 497:80-85(2013).
CC -!- FUNCTION: Structural component of the ribosome (PubMed:23636399).
CC Required for proper erythropoiesis (PubMed:27909223).
CC {ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:27909223}.
CC -!- SUBUNIT: Component of the 40S ribosomal subunit.
CC {ECO:0000269|PubMed:23636399}.
CC -!- INTERACTION:
CC P62244; P22607: FGFR3; NbExp=3; IntAct=EBI-347895, EBI-348399;
CC P62244; P28799: GRN; NbExp=3; IntAct=EBI-347895, EBI-747754;
CC P62244; P06396: GSN; NbExp=3; IntAct=EBI-347895, EBI-351506;
CC P62244; P04792: HSPB1; NbExp=3; IntAct=EBI-347895, EBI-352682;
CC P62244; P42858: HTT; NbExp=3; IntAct=EBI-347895, EBI-466029;
CC P62244; O60333-2: KIF1B; NbExp=3; IntAct=EBI-347895, EBI-10975473;
CC P62244; D3DTS7: PMP22; NbExp=3; IntAct=EBI-347895, EBI-25882629;
CC P62244; Q9Y3C5: RNF11; NbExp=3; IntAct=EBI-347895, EBI-396669;
CC P62244; O76024: WFS1; NbExp=3; IntAct=EBI-347895, EBI-720609;
CC -!- DISEASE: Diamond-Blackfan anemia 20 (DBA20) [MIM:618313]: A form of
CC Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic
CC anemia that usually presents early in infancy. Diamond-Blackfan anemia
CC is characterized by a moderate to severe macrocytic anemia,
CC erythroblastopenia, and an increased risk of malignancy. 30 to 40% of
CC Diamond-Blackfan anemia patients present with short stature and
CC congenital anomalies, the most frequent being craniofacial (Pierre-
CC Robin syndrome and cleft palate), thumb and urogenital anomalies. DBA20
CC inheritance is autosomal dominant. {ECO:0000269|PubMed:27909223}.
CC Note=The disease may be caused by variants affecting the gene
CC represented in this entry.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS8 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA44568.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X62691; CAA44568.1; ALT_FRAME; mRNA.
DR EMBL; X84407; CAA59127.1; -; mRNA.
DR EMBL; AY208299; AAO48936.1; -; mRNA.
DR EMBL; AB062400; BAB93487.1; -; mRNA.
DR EMBL; BC001697; AAH01697.1; -; mRNA.
DR EMBL; BC030569; AAH30569.1; -; mRNA.
DR EMBL; BC046113; AAH46113.1; -; mRNA.
DR EMBL; BC105273; AAI05274.1; -; mRNA.
DR EMBL; BC105292; AAI05293.1; -; mRNA.
DR EMBL; AB007154; BAA28592.1; -; Genomic_DNA.
DR CCDS; CCDS10571.1; -.
DR PIR; S52339; S52339.
DR RefSeq; NP_001010.2; NM_001019.4.
DR RefSeq; NP_001025180.1; NM_001030009.1.
DR PDB; 4UG0; EM; -; SW=1-130.
DR PDB; 4V6X; EM; 5.00 A; AW=1-130.
DR PDB; 5A2Q; EM; 3.90 A; W=1-130.
DR PDB; 5AJ0; EM; 3.50 A; BW=1-130.
DR PDB; 5FLX; EM; 3.90 A; W=1-130.
DR PDB; 5LKS; EM; 3.60 A; SW=1-130.
DR PDB; 5OA3; EM; 4.30 A; W=1-130.
DR PDB; 5T2C; EM; 3.60 A; AP=1-130.
DR PDB; 5VYC; X-ray; 6.00 A; W1/W2/W3/W4/W5/W6=1-130.
DR PDB; 6FEC; EM; 6.30 A; a=2-130.
DR PDB; 6G18; EM; 3.60 A; W=1-130.
DR PDB; 6G4S; EM; 4.00 A; W=1-130.
DR PDB; 6G4W; EM; 4.50 A; W=1-130.
DR PDB; 6G51; EM; 4.10 A; W=1-130.
DR PDB; 6G53; EM; 4.50 A; W=1-130.
DR PDB; 6G5H; EM; 3.60 A; W=1-130.
DR PDB; 6G5I; EM; 3.50 A; W=1-130.
DR PDB; 6IP5; EM; 3.90 A; 3M=1-130.
DR PDB; 6IP6; EM; 4.50 A; 3M=1-130.
DR PDB; 6IP8; EM; 3.90 A; 3M=1-130.
DR PDB; 6OLE; EM; 3.10 A; SW=2-130.
DR PDB; 6OLF; EM; 3.90 A; SW=2-130.
DR PDB; 6OLG; EM; 3.40 A; BW=2-130.
DR PDB; 6OLI; EM; 3.50 A; SW=2-130.
DR PDB; 6OLZ; EM; 3.90 A; BW=2-130.
DR PDB; 6OM0; EM; 3.10 A; SW=2-130.
DR PDB; 6OM7; EM; 3.70 A; SW=2-130.
DR PDB; 6QZP; EM; 2.90 A; SW=2-130.
DR PDB; 6XA1; EM; 2.80 A; SW=2-130.
DR PDB; 6Y0G; EM; 3.20 A; SW=1-130.
DR PDB; 6Y2L; EM; 3.00 A; SW=1-130.
DR PDB; 6Y57; EM; 3.50 A; SW=1-130.
DR PDB; 6YBW; EM; 3.10 A; J=1-130.
DR PDB; 6Z6L; EM; 3.00 A; SW=1-130.
DR PDB; 6Z6M; EM; 3.10 A; SW=1-130.
DR PDB; 6Z6N; EM; 2.90 A; SW=1-130.
DR PDB; 6ZLW; EM; 2.60 A; W=1-130.
DR PDB; 6ZM7; EM; 2.70 A; SW=1-130.
DR PDB; 6ZME; EM; 3.00 A; SW=1-130.
DR PDB; 6ZMI; EM; 2.60 A; SW=1-130.
DR PDB; 6ZMO; EM; 3.10 A; SW=1-130.
DR PDB; 6ZMT; EM; 3.00 A; W=1-130.
DR PDB; 6ZMW; EM; 3.70 A; J=1-130.
DR PDB; 6ZN5; EM; 3.20 A; W=2-130.
DR PDB; 6ZOJ; EM; 2.80 A; W=1-130.
DR PDB; 6ZOK; EM; 2.80 A; W=1-130.
DR PDB; 6ZON; EM; 3.00 A; f=1-130.
DR PDB; 6ZP4; EM; 2.90 A; D=1-130.
DR PDB; 6ZUO; EM; 3.10 A; W=1-130.
DR PDB; 6ZV6; EM; 2.90 A; W=1-130.
DR PDB; 6ZVH; EM; 2.90 A; W=2-130.
DR PDB; 6ZVJ; EM; 3.80 A; f=2-130.
DR PDB; 6ZXD; EM; 3.20 A; W=1-130.
DR PDB; 6ZXE; EM; 3.00 A; W=1-130.
DR PDB; 6ZXF; EM; 3.70 A; W=1-130.
DR PDB; 6ZXG; EM; 2.60 A; W=1-130.
DR PDB; 6ZXH; EM; 2.70 A; W=1-130.
DR PDB; 7A09; EM; 3.50 A; D=1-130.
DR PDB; 7K5I; EM; 2.90 A; W=1-130.
DR PDB; 7MQ8; EM; 3.60 A; NO=1-130.
DR PDB; 7MQ9; EM; 3.87 A; NO=1-130.
DR PDB; 7MQA; EM; 2.70 A; NO=1-130.
DR PDBsum; 4UG0; -.
DR PDBsum; 4V6X; -.
DR PDBsum; 5A2Q; -.
DR PDBsum; 5AJ0; -.
DR PDBsum; 5FLX; -.
DR PDBsum; 5LKS; -.
DR PDBsum; 5OA3; -.
DR PDBsum; 5T2C; -.
DR PDBsum; 5VYC; -.
DR PDBsum; 6FEC; -.
DR PDBsum; 6G18; -.
DR PDBsum; 6G4S; -.
DR PDBsum; 6G4W; -.
DR PDBsum; 6G51; -.
DR PDBsum; 6G53; -.
DR PDBsum; 6G5H; -.
DR PDBsum; 6G5I; -.
DR PDBsum; 6IP5; -.
DR PDBsum; 6IP6; -.
DR PDBsum; 6IP8; -.
DR PDBsum; 6OLE; -.
DR PDBsum; 6OLF; -.
DR PDBsum; 6OLG; -.
DR PDBsum; 6OLI; -.
DR PDBsum; 6OLZ; -.
DR PDBsum; 6OM0; -.
DR PDBsum; 6OM7; -.
DR PDBsum; 6QZP; -.
DR PDBsum; 6XA1; -.
DR PDBsum; 6Y0G; -.
DR PDBsum; 6Y2L; -.
DR PDBsum; 6Y57; -.
DR PDBsum; 6YBW; -.
DR PDBsum; 6Z6L; -.
DR PDBsum; 6Z6M; -.
DR PDBsum; 6Z6N; -.
DR PDBsum; 6ZLW; -.
DR PDBsum; 6ZM7; -.
DR PDBsum; 6ZME; -.
DR PDBsum; 6ZMI; -.
DR PDBsum; 6ZMO; -.
DR PDBsum; 6ZMT; -.
DR PDBsum; 6ZMW; -.
DR PDBsum; 6ZN5; -.
DR PDBsum; 6ZOJ; -.
DR PDBsum; 6ZOK; -.
DR PDBsum; 6ZON; -.
DR PDBsum; 6ZP4; -.
DR PDBsum; 6ZUO; -.
DR PDBsum; 6ZV6; -.
DR PDBsum; 6ZVH; -.
DR PDBsum; 6ZVJ; -.
DR PDBsum; 6ZXD; -.
DR PDBsum; 6ZXE; -.
DR PDBsum; 6ZXF; -.
DR PDBsum; 6ZXG; -.
DR PDBsum; 6ZXH; -.
DR PDBsum; 7A09; -.
DR PDBsum; 7K5I; -.
DR PDBsum; 7MQ8; -.
DR PDBsum; 7MQ9; -.
DR PDBsum; 7MQA; -.
DR AlphaFoldDB; P62244; -.
DR SMR; P62244; -.
DR BioGRID; 112124; 320.
DR ComplexPortal; CPX-5223; 40S cytosolic small ribosomal subunit.
DR CORUM; P62244; -.
DR IntAct; P62244; 76.
DR MINT; P62244; -.
DR STRING; 9606.ENSP00000318646; -.
DR GlyGen; P62244; 1 site, 1 O-linked glycan (1 site).
DR iPTMnet; P62244; -.
DR MetOSite; P62244; -.
DR PhosphoSitePlus; P62244; -.
DR SwissPalm; P62244; -.
DR BioMuta; RPS15A; -.
DR DMDM; 50403624; -.
DR SWISS-2DPAGE; P62244; -.
DR EPD; P62244; -.
DR jPOST; P62244; -.
DR MassIVE; P62244; -.
DR MaxQB; P62244; -.
DR PaxDb; P62244; -.
DR PeptideAtlas; P62244; -.
DR PRIDE; P62244; -.
DR ProteomicsDB; 57373; -.
DR TopDownProteomics; P62244; -.
DR Antibodypedia; 42904; 99 antibodies from 20 providers.
DR DNASU; 6210; -.
DR Ensembl; ENST00000322989.8; ENSP00000318646.4; ENSG00000134419.15.
DR Ensembl; ENST00000563390.5; ENSP00000457000.1; ENSG00000134419.15.
DR Ensembl; ENST00000565420.5; ENSP00000458115.1; ENSG00000134419.15.
DR Ensembl; ENST00000572008.5; ENSP00000458528.1; ENSG00000134419.15.
DR GeneID; 6210; -.
DR KEGG; hsa:6210; -.
DR MANE-Select; ENST00000322989.8; ENSP00000318646.4; NM_001019.5; NP_001010.2.
DR UCSC; uc002dfh.2; human.
DR CTD; 6210; -.
DR DisGeNET; 6210; -.
DR GeneCards; RPS15A; -.
DR GeneReviews; RPS15A; -.
DR HGNC; HGNC:10389; RPS15A.
DR HPA; ENSG00000134419; Low tissue specificity.
DR MalaCards; RPS15A; -.
DR MIM; 603674; gene.
DR MIM; 618313; phenotype.
DR neXtProt; NX_P62244; -.
DR OpenTargets; ENSG00000134419; -.
DR Orphanet; 124; Blackfan-Diamond anemia.
DR PharmGKB; PA34788; -.
DR VEuPathDB; HostDB:ENSG00000134419; -.
DR eggNOG; KOG1754; Eukaryota.
DR GeneTree; ENSGT00950000183198; -.
DR HOGENOM; CLU_098428_1_1_1; -.
DR InParanoid; P62244; -.
DR OMA; LPAKNFG; -.
DR OrthoDB; 1417658at2759; -.
DR PhylomeDB; P62244; -.
DR TreeFam; TF300067; -.
DR PathwayCommons; P62244; -.
DR Reactome; R-HSA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-HSA-156902; Peptide chain elongation.
DR Reactome; R-HSA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-HSA-192823; Viral mRNA Translation.
DR Reactome; R-HSA-2408557; Selenocysteine synthesis.
DR Reactome; R-HSA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-HSA-72649; Translation initiation complex formation.
DR Reactome; R-HSA-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-HSA-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR Reactome; R-HSA-72702; Ribosomal scanning and start codon recognition.
DR Reactome; R-HSA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-HSA-72764; Eukaryotic Translation Termination.
DR Reactome; R-HSA-9010553; Regulation of expression of SLITs and ROBOs.
DR Reactome; R-HSA-9633012; Response of EIF2AK4 (GCN2) to amino acid deficiency.
DR Reactome; R-HSA-9754678; SARS-CoV-2 modulates host translation machinery.
DR Reactome; R-HSA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-HSA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR SignaLink; P62244; -.
DR SIGNOR; P62244; -.
DR BioGRID-ORCS; 6210; 805 hits in 1059 CRISPR screens.
DR ChiTaRS; RPS15A; human.
DR GeneWiki; RPS15A; -.
DR GenomeRNAi; 6210; -.
DR Pharos; P62244; Tbio.
DR PRO; PR:P62244; -.
DR Proteomes; UP000005640; Chromosome 16.
DR RNAct; P62244; protein.
DR Bgee; ENSG00000134419; Expressed in ganglionic eminence and 160 other tissues.
DR ExpressionAtlas; P62244; baseline and differential.
DR Genevisible; P62244; HS.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0005829; C:cytosol; TAS:Reactome.
DR GO; GO:0022626; C:cytosolic ribosome; IDA:FlyBase.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB.
DR GO; GO:0016020; C:membrane; HDA:UniProtKB.
DR GO; GO:0005654; C:nucleoplasm; TAS:Reactome.
DR GO; GO:0003723; F:RNA binding; HDA:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; IDA:FlyBase.
DR GO; GO:0002181; P:cytoplasmic translation; IC:FlyBase.
DR GO; GO:0045787; P:positive regulation of cell cycle; IDA:UniProtKB.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IDA:UniProtKB.
DR GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR GO; GO:0006412; P:translation; NAS:UniProtKB.
DR HAMAP; MF_01302_A; Ribosomal_S8_A; 1.
DR InterPro; IPR000630; Ribosomal_S8.
DR InterPro; IPR035987; Ribosomal_S8_sf.
DR PANTHER; PTHR11758; PTHR11758; 1.
DR Pfam; PF00410; Ribosomal_S8; 1.
DR SUPFAM; SSF56047; SSF56047; 1.
DR PROSITE; PS00053; RIBOSOMAL_S8; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Diamond-Blackfan anemia; Direct protein sequencing;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:8706699"
FT CHAIN 2..130
FT /note="40S ribosomal protein S15a"
FT /id="PRO_0000126602"
FT MOD_RES 88
FT /note="N6-succinyllysine"
FT /evidence="ECO:0000250|UniProtKB:P62245"
FT CONFLICT 3
FT /note="R -> C (in Ref. 6; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 40
FT /note="V -> L (in Ref. 2; CAA59127)"
FT /evidence="ECO:0000305"
FT CONFLICT 79
FT /note="F -> S (in Ref. 5; AAH01697)"
FT /evidence="ECO:0000305"
FT HELIX 6..19
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 23..27
FT /evidence="ECO:0007829|PDB:6ZLW"
FT HELIX 32..43
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 50..53
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 56..58
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 60..64
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 70..74
FT /evidence="ECO:0007829|PDB:6ZLW"
FT HELIX 83..85
FT /evidence="ECO:0007829|PDB:6ZLW"
FT HELIX 86..93
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 97..99
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 101..106
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 109..112
FT /evidence="ECO:0007829|PDB:6ZLW"
FT HELIX 113..118
FT /evidence="ECO:0007829|PDB:6ZLW"
FT STRAND 123..130
FT /evidence="ECO:0007829|PDB:6ZLW"
SQ SEQUENCE 130 AA; 14840 MW; D4AC1E8864E3A184 CRC64;
MVRMNVLADA LKSINNAEKR GKRQVLIRPC SKVIVRFLTV MMKHGYIGEF EIIDDHRAGK
IVVNLTGRLN KCGVISPRFD VQLKDLEKWQ NNLLPSRQFG FIVLTTSAGI MDHEEARRKH
TGGKILGFFF
