RS15_GEOSE
ID RS15_GEOSE Reviewed; 89 AA.
AC P05766;
DT 01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=30S ribosomal protein S15 {ECO:0000255|HAMAP-Rule:MF_01343};
DE AltName: Full=BS18;
GN Name=rpsO {ECO:0000255|HAMAP-Rule:MF_01343};
OS Geobacillus stearothermophilus (Bacillus stearothermophilus).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX NCBI_TaxID=1422;
RN [1]
RP PROTEIN SEQUENCE OF 2-89.
RX PubMed=1764513; DOI=10.1016/0300-9084(91)90045-3;
RA Arndt E., Scholzen T., Kromer W., Hatakeyama T., Kimura M.;
RT "Primary structures of ribosomal proteins from the archaebacterium
RT Halobacterium marismortui and the eubacterium Bacillus
RT stearothermophilus.";
RL Biochimie 73:657-668(1991).
RN [2]
RP PROTEIN SEQUENCE OF 2-16.
RC STRAIN=DSM 13240 / CIP 106956 / 10;
RX PubMed=4607606; DOI=10.1016/0014-5793(74)80391-1;
RA Yaguchi M., Matheson A.T., Visentin L.P.;
RT "Procaryotic ribosomal proteins: N-terminal sequence homologies and
RT structural correspondence of 30 S ribosomal proteins from Escherichia coli
RT and Bacillus stearothermophilus.";
RL FEBS Lett. 46:296-300(1974).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS), AND SEQUENCE REVISION TO 46.
RX PubMed=9562554; DOI=10.1016/s0969-2126(98)00045-8;
RA Clemons W.M. Jr., Davies C., White S.W., Ramakrishnan V.;
RT "Conformational variability of the N-terminal helix in the structure of
RT ribosomal protein S15.";
RL Structure 6:429-438(1998).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC to 16S rRNA where it helps nucleate assembly of the platform of the 30S
CC subunit by binding and bridging several RNA helices of the 16S rRNA.
CC {ECO:0000255|HAMAP-Rule:MF_01343}.
CC -!- FUNCTION: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of
CC the 50S subunit in the ribosome. {ECO:0000255|HAMAP-Rule:MF_01343}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Forms a bridge to the 50S
CC subunit in the 70S ribosome, contacting the 23S rRNA.
CC {ECO:0000255|HAMAP-Rule:MF_01343}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS15 family.
CC {ECO:0000255|HAMAP-Rule:MF_01343}.
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DR RefSeq; WP_033016867.1; NZ_RCTK01000001.1.
DR PDB; 1A32; X-ray; 2.10 A; A=2-89.
DR PDBsum; 1A32; -.
DR AlphaFoldDB; P05766; -.
DR SMR; P05766; -.
DR IntAct; P05766; 6.
DR GeneID; 58572351; -.
DR EvolutionaryTrace; P05766; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00353; Ribosomal_S15p_S13e; 1.
DR HAMAP; MF_01343_B; Ribosomal_S15_B; 1.
DR InterPro; IPR000589; Ribosomal_S15.
DR InterPro; IPR005290; Ribosomal_S15_bac-type.
DR InterPro; IPR009068; S15_NS1_RNA-bd.
DR PANTHER; PTHR23321; PTHR23321; 1.
DR Pfam; PF00312; Ribosomal_S15; 1.
DR SMART; SM01387; Ribosomal_S15; 1.
DR SUPFAM; SSF47060; SSF47060; 1.
DR TIGRFAMs; TIGR00952; S15_bact; 1.
DR PROSITE; PS00362; RIBOSOMAL_S15; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding; rRNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:1764513,
FT ECO:0000269|PubMed:4607606"
FT CHAIN 2..89
FT /note="30S ribosomal protein S15"
FT /id="PRO_0000115380"
FT CONFLICT 13..14
FT /note="EQ -> GE (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 46
FT /note="H -> R (in Ref. 1; AA sequence)"
FT /evidence="ECO:0000305"
FT HELIX 5..14
FT /evidence="ECO:0007829|PDB:1A32"
FT HELIX 25..45
FT /evidence="ECO:0007829|PDB:1A32"
FT HELIX 51..73
FT /evidence="ECO:0007829|PDB:1A32"
FT HELIX 75..85
FT /evidence="ECO:0007829|PDB:1A32"
SQ SEQUENCE 89 AA; 10691 MW; B0387CC4B04DE000 CRC64;
MALTQERKRE IIEQFKVHEN DTGSPEVQIA ILTEQINNLN EHLRVHKKDH HSRRGLLKMV
GKRRRLLAYL RNKDVARYRE IVEKLGLRR
