RS15_MYCS2
ID RS15_MYCS2 Reviewed; 89 AA.
AC A0QVQ3; I7G919;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=30S ribosomal protein S15 {ECO:0000255|HAMAP-Rule:MF_01343};
GN Name=rpsO {ECO:0000255|HAMAP-Rule:MF_01343};
GN OrderedLocusNames=MSMEG_2654, MSMEI_2591;
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT mutations or sequencing errors?";
RL Genome Biol. 8:R20.1-R20.9(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS], AND CLEAVAGE OF INITIATOR METHIONINE.
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=18955433; DOI=10.1101/gr.081901.108;
RA Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT and a new MS-based protocol.";
RL Genome Res. 19:128-135(2009).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC to 16S rRNA where it helps nucleate assembly of the platform of the 30S
CC subunit by binding and bridging several RNA helices of the 16S rRNA.
CC {ECO:0000255|HAMAP-Rule:MF_01343}.
CC -!- FUNCTION: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of
CC the 50S subunit in the ribosome. {ECO:0000255|HAMAP-Rule:MF_01343}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Forms a bridge to the 50S
CC subunit in the 70S ribosome, contacting the 23S rRNA.
CC {ECO:0000255|HAMAP-Rule:MF_01343}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS15 family.
CC {ECO:0000255|HAMAP-Rule:MF_01343}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000480; ABK73765.1; -; Genomic_DNA.
DR EMBL; CP001663; AFP39059.1; -; Genomic_DNA.
DR RefSeq; WP_003894036.1; NZ_SIJM01000064.1.
DR RefSeq; YP_886991.1; NC_008596.1.
DR PDB; 5O5J; EM; 3.45 A; O=1-89.
DR PDB; 5O61; EM; 3.31 A; BO=1-89.
DR PDB; 5XYU; EM; 3.45 A; O=1-89.
DR PDB; 5ZEB; EM; 3.40 A; o=1-89.
DR PDB; 5ZEP; EM; 3.40 A; o=1-89.
DR PDB; 5ZEU; EM; 3.70 A; o=1-89.
DR PDB; 6DZI; EM; 3.46 A; x=2-89.
DR PDB; 6DZK; EM; 3.60 A; O=2-89.
DR PDBsum; 5O5J; -.
DR PDBsum; 5O61; -.
DR PDBsum; 5XYU; -.
DR PDBsum; 5ZEB; -.
DR PDBsum; 5ZEP; -.
DR PDBsum; 5ZEU; -.
DR PDBsum; 6DZI; -.
DR PDBsum; 6DZK; -.
DR AlphaFoldDB; A0QVQ3; -.
DR SMR; A0QVQ3; -.
DR IntAct; A0QVQ3; 2.
DR STRING; 246196.MSMEI_2591; -.
DR PRIDE; A0QVQ3; -.
DR EnsemblBacteria; ABK73765; ABK73765; MSMEG_2654.
DR EnsemblBacteria; AFP39059; AFP39059; MSMEI_2591.
DR GeneID; 66734063; -.
DR KEGG; msg:MSMEI_2591; -.
DR KEGG; msm:MSMEG_2654; -.
DR PATRIC; fig|246196.19.peg.2620; -.
DR eggNOG; COG0184; Bacteria.
DR OMA; FKTHVKD; -.
DR OrthoDB; 1990141at2; -.
DR Proteomes; UP000000757; Chromosome.
DR Proteomes; UP000006158; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00353; Ribosomal_S15p_S13e; 1.
DR HAMAP; MF_01343_B; Ribosomal_S15_B; 1.
DR InterPro; IPR000589; Ribosomal_S15.
DR InterPro; IPR005290; Ribosomal_S15_bac-type.
DR InterPro; IPR009068; S15_NS1_RNA-bd.
DR PANTHER; PTHR23321; PTHR23321; 1.
DR Pfam; PF00312; Ribosomal_S15; 1.
DR SMART; SM01387; Ribosomal_S15; 1.
DR SUPFAM; SSF47060; SSF47060; 1.
DR TIGRFAMs; TIGR00952; S15_bact; 1.
DR PROSITE; PS00362; RIBOSOMAL_S15; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:18955433"
FT CHAIN 2..89
FT /note="30S ribosomal protein S15"
FT /id="PRO_1000054819"
FT HELIX 5..15
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 17..20
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 25..46
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 50..73
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 75..85
FT /evidence="ECO:0007829|PDB:5XYU"
SQ SEQUENCE 89 AA; 10344 MW; A5711F279E833190 CRC64;
MALTAEQKKE ILGQYGLHDT DTGSPEAQVA LLTKRIQDLT EHLKVHKHDH HSRRGLLLLV
GRRRRLLKYV AQVDVARYRS LIERLGLRR
