ID   B2CYB_RANDY             Reviewed;          33 AA.
AC   P86042;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 17.
DE   RecName: Full=Brevinin-2CDYb {ECO:0000303|PubMed:19539775};
OS   Rana dybowskii (Dybovsky's frog) (Korean brown frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Rana.
OX   NCBI_TaxID=71582;
RN   [1]
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Skin secretion;
RX   PubMed=19539775; DOI=10.1016/j.cbpb.2009.05.015;
RA   Jin L.-L., Li Q., Song S.-S., Feng K., Zhang D.-B., Wang Q.-Y., Chen Y.-H.;
RT   "Characterization of antimicrobial peptides isolated from the skin of the
RT   Chinese frog, Rana dybowskii.";
RL   Comp. Biochem. Physiol. 154B:174-178(2009).
CC   -!- FUNCTION: Antimicrobial peptide. {ECO:0000250|UniProtKB:P84114}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19539775,
CC       ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC       {ECO:0000269|PubMed:19539775, ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Brevinin subfamily. {ECO:0000255}.
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DR   AlphaFoldDB; P86042; -.
DR   SMR; P86042; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR012521; Antimicrobial_frog_2.
DR   Pfam; PF08023; Antimicrobial_2; 1.
PE   1: Evidence at protein level;
KW   Amphibian defense peptide; Antibiotic; Antimicrobial;
KW   Direct protein sequencing; Disulfide bond; Secreted.
FT   PEPTIDE         1..33
FT                   /note="Brevinin-2CDYb"
FT                   /evidence="ECO:0000269|PubMed:19539775"
FT                   /id="PRO_0000354977"
FT   DISULFID        27..33
FT                   /evidence="ECO:0000250|UniProtKB:P84114"
SQ   SEQUENCE   33 AA;  3277 MW;  DCB244A213FBAA52 CRC64;
     GLFSVVTGVL KAVGKNVAGS LLEQLKCKIS GGC