RS18_ARATH
ID RS18_ARATH Reviewed; 152 AA.
AC P34788; Q94K22;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 25-MAY-2022, entry version 166.
DE RecName: Full=40S ribosomal protein S18;
GN Name=RPS18A; Synonyms=PFL; OrderedLocusNames=At1g22780; ORFNames=T22J18.5;
GN and
GN Name=RPS18B; OrderedLocusNames=At1g34030; ORFNames=F12G12.15, T15K4.9;
GN and
GN Name=RPS18C; OrderedLocusNames=At4g09800; ORFNames=F17A8.150;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND PROTEIN SEQUENCE OF 56-64 AND
RP 95-106 (RPS18A AND RPS18B).
RC STRAIN=cv. C24, and cv. Columbia;
RX PubMed=7913892;
RA van Lijsebettens M., Vanderhaeghen R., de Block M., Bauw G., Villarroel R.,
RA Lister C., Dean C., van Montagu M.;
RT "An S18 ribosomal protein gene copy at the Arabidopsis PFL locus affects
RT plant development by its specific expression in meristems.";
RL EMBO J. 13:3378-3388(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] (RPS18A).
RC STRAIN=cv. Columbia;
RX PubMed=9369203; DOI=10.1016/s0014-5793(97)01190-3;
RA Terryn N., Neyt P., de Clercq R., de Keyser A., van den Daele H.,
RA Ardiles W., Dehais P., Rouze P., Gielen J., Villarroel R., van Montagu M.;
RT "Sequence analysis of a 24-kb contiguous genomic region at the Arabidopsis
RT thaliana PFL locus on chromosome 1.";
RL FEBS Lett. 416:156-160(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (RPS18A AND RPS18B).
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (RPS18C).
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (RPS18A; RPS18B AND RPS18C).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (RPS18A).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=11598216; DOI=10.1104/pp.010265;
RA Barakat A., Szick-Miranda K., Chang I.-F., Guyot R., Blanc G., Cooke R.,
RA Delseny M., Bailey-Serres J.;
RT "The organization of cytoplasmic ribosomal protein genes in the Arabidopsis
RT genome.";
RL Plant Physiol. 127:398-415(2001).
RN [9]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=17272265; DOI=10.1074/mcp.m600408-mcp200;
RA Maor R., Jones A., Nuehse T.S., Studholme D.J., Peck S.C., Shirasu K.;
RT "Multidimensional protein identification technology (MudPIT) analysis of
RT ubiquitinated proteins in plants.";
RL Mol. Cell. Proteomics 6:601-610(2007).
RN [10]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- FUNCTION: Located at the top of the head of the 40S subunit, it
CC contacts several helices of the 18S rRNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS13 family.
CC {ECO:0000305}.
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DR EMBL; Z23165; CAA80684.1; -; Genomic_DNA.
DR EMBL; Z28701; CAA82273.1; -; mRNA.
DR EMBL; Z28702; CAA82274.1; -; mRNA.
DR EMBL; Z28962; CAA82275.1; -; Genomic_DNA.
DR EMBL; Y12227; CAA72909.1; -; Genomic_DNA.
DR EMBL; AC003979; AAC25506.1; -; Genomic_DNA.
DR EMBL; AC015446; AAG12534.1; -; Genomic_DNA.
DR EMBL; AC079286; AAG12853.1; -; Genomic_DNA.
DR EMBL; AL049482; CAB39647.1; -; Genomic_DNA.
DR EMBL; AL161515; CAB78103.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30287.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31659.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82800.1; -; Genomic_DNA.
DR EMBL; AF411781; AAL06471.1; -; mRNA.
DR EMBL; AF386941; AAK62386.1; -; mRNA.
DR EMBL; AF370463; AAK43840.1; -; mRNA.
DR EMBL; AY034965; AAK59471.1; -; mRNA.
DR EMBL; AY064680; AAL47385.1; -; mRNA.
DR EMBL; AY070029; AAL47500.1; -; mRNA.
DR EMBL; AY086334; AAM64403.1; -; mRNA.
DR EMBL; AY086800; AAM63849.1; -; mRNA.
DR EMBL; BT006539; AAP21347.1; -; mRNA.
DR EMBL; AY087428; AAM64976.1; -; mRNA.
DR PIR; S46223; S37496.
DR RefSeq; NP_173692.1; NM_102125.4.
DR RefSeq; NP_192718.1; NM_117048.4.
DR RefSeq; NP_564434.1; NM_103125.5.
DR AlphaFoldDB; P34788; -.
DR SMR; P34788; -.
DR BioGRID; 11868; 152.
DR BioGRID; 24123; 152.
DR BioGRID; 25532; 150.
DR IntAct; P34788; 3.
DR STRING; 3702.AT1G22780.1; -.
DR iPTMnet; P34788; -.
DR MetOSite; P34788; -.
DR PaxDb; P34788; -.
DR PRIDE; P34788; -.
DR ProteomicsDB; 226879; -.
DR EnsemblPlants; AT1G22780.1; AT1G22780.1; AT1G22780.
DR EnsemblPlants; AT1G34030.1; AT1G34030.1; AT1G34030.
DR EnsemblPlants; AT4G09800.1; AT4G09800.1; AT4G09800.
DR GeneID; 826569; -.
DR GeneID; 838884; -.
DR GeneID; 840300; -.
DR Gramene; AT1G22780.1; AT1G22780.1; AT1G22780.
DR Gramene; AT1G34030.1; AT1G34030.1; AT1G34030.
DR Gramene; AT4G09800.1; AT4G09800.1; AT4G09800.
DR KEGG; ath:AT1G22780; -.
DR KEGG; ath:AT1G34030; -.
DR KEGG; ath:AT4G09800; -.
DR Araport; AT1G22780; -.
DR Araport; AT1G34030; -.
DR Araport; AT4G09800; -.
DR TAIR; locus:2005541; AT4G09800.
DR TAIR; locus:2009066; AT1G34030.
DR TAIR; locus:2199670; AT1G22780.
DR eggNOG; KOG3311; Eukaryota.
DR HOGENOM; CLU_103849_0_1_1; -.
DR InParanoid; P34788; -.
DR OMA; IRAYRGI; -.
DR OrthoDB; 1343043at2759; -.
DR PhylomeDB; P34788; -.
DR PRO; PR:P34788; -.
DR Proteomes; UP000006548; Chromosome 1.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; P34788; baseline and differential.
DR Genevisible; P34788; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0022626; C:cytosolic ribosome; HDA:TAIR.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; HDA:TAIR.
DR GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0009505; C:plant-type cell wall; HDA:TAIR.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IDA:CAFA.
DR GO; GO:0006413; P:translational initiation; TAS:TAIR.
DR Gene3D; 4.10.910.10; -; 1.
DR HAMAP; MF_01315; Ribosomal_S13_S18; 1.
DR InterPro; IPR027437; 30s_Rbsml_prot_S13_C.
DR InterPro; IPR001892; Ribosomal_S13.
DR InterPro; IPR010979; Ribosomal_S13-like_H2TH.
DR InterPro; IPR018269; Ribosomal_S13_CS.
DR Pfam; PF00416; Ribosomal_S13; 1.
DR PIRSF; PIRSF002134; Ribosomal_S13; 1.
DR SUPFAM; SSF46946; SSF46946; 1.
DR PROSITE; PS00646; RIBOSOMAL_S13_1; 1.
DR PROSITE; PS50159; RIBOSOMAL_S13_2; 1.
PE 1: Evidence at protein level;
KW Acetylation; Cytoplasm; Direct protein sequencing; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..152
FT /note="40S ribosomal protein S18"
FT /id="PRO_0000132224"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CONFLICT 48
FT /note="A -> T (in Ref. 6; AAK43840/AAL47385)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 152 AA; 17545 MW; 4D060D6614A85092 CRC64;
MSLVANEEFQ HILRVLNTNV DGKQKIMFAL TSIKGIGRRL ANIVCKKADV DMNKRAGELS
AAEIDNLMTI VANPRQFKIP DWFLNRQKDY KDGKYSQVVS NALDMKLRDD LERLKKIRNH
RGLRHYWGLR VRGQHTKTTG RRGKTVGVSK KR
