ID   B2_BOOLV                Reviewed;         106 AA.
AC   Q992I9;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   02-JUN-2021, entry version 36.
DE   RecName: Full=Protein B2;
GN   Name=B2;
OS   Boolarra virus (BoV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Magsaviricetes;
OC   Nodamuvirales; Nodaviridae; Alphanodavirus.
OX   NCBI_TaxID=12286;
OH   NCBI_TaxID=41021; Hepialidae (ghost moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Dasgupta R., Ye B., Harper T.A.;
RL   Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds double-strand RNA (dsRNA) with high affinity.
CC       Suppresses the host RNA silencing-based antiviral response (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Expressed at high levels early in the viral
CC       replication cycle.
CC   -!- DOMAIN: The dsRNA-binding region is required for suppression of RNA
CC       silencing. {ECO:0000250}.
CC   -!- MISCELLANEOUS: Encoded on a subgenomic RNA (RNA3) synthesized during
CC       replication and which is co-terminal with RNA1.
CC   -!- SIMILARITY: Belongs to the nodaviridae B2 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF329080; AAK15752.1; -; Genomic_RNA.
DR   RefSeq; NP_689440.1; NC_004142.1.
DR   SMR; Q992I9; -.
DR   GeneID; 956657; -.
DR   KEGG; vg:956657; -.
DR   Proteomes; UP000204043; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR024377; RNA-bd_B2.
DR   InterPro; IPR037209; RNA-bd_B2_sf.
DR   Pfam; PF11473; B2; 1.
DR   SUPFAM; SSF140506; SSF140506; 1.
PE   2: Evidence at transcript level;
KW   RNA-binding; Suppressor of RNA silencing.
FT   CHAIN           1..106
FT                   /note="Protein B2"
FT                   /id="PRO_0000223689"
FT   REGION          1..73
FT                   /note="RNA-binding"
FT                   /evidence="ECO:0000250"
FT   REGION          85..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   106 AA;  12004 MW;  94E05B689304BCA4 CRC64;
     MQSKLALIQE LPDRIQKAVE VVLAMSYQEA PNNVRRDLDN LQACLNKAKQ TVNRMVTSLL
     DKPSMAAYLE GKPLPEERPT LEERLRKLEL SREPPPTRSD PAPAKL