B3GT7_ARATH
ID B3GT7_ARATH Reviewed; 393 AA.
AC Q6NQB7; Q3ECB6; Q9CA13; Q9SH19;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Beta-1,3-galactosyltransferase 7;
DE EC=2.4.1.-;
GN Name=B3GALT7; OrderedLocusNames=At1g77810; ORFNames=F28K19.2, T32E8.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=18548197; DOI=10.1007/s11103-008-9351-3;
RA Qu Y., Egelund J., Gilson P.R., Houghton F., Gleeson P.A., Schultz C.J.,
RA Bacic A.;
RT "Identification of a novel group of putative Arabidopsis thaliana beta-
RT (1,3)-galactosyltransferases.";
RL Plant Mol. Biol. 68:43-59(2008).
CC -!- FUNCTION: Beta-1,3-galactosyltransferase that transfers galactose from
CC UDP-galactose to substrates with a terminal glycosyl residue.
CC {ECO:0000269|PubMed:18548197}.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000305};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000269|PubMed:18548197}; Single-pass type II membrane protein
CC {ECO:0000269|PubMed:18548197}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q6NQB7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6NQB7-2; Sequence=VSP_036146, VSP_036147;
CC -!- TISSUE SPECIFICITY: Expressed in leaves, stems, flowers and siliques.
CC {ECO:0000269|PubMed:18548197}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF17702.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAG51626.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009243; AAF17702.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC012193; AAG51626.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE36030.1; -; Genomic_DNA.
DR EMBL; BT010541; AAQ65164.1; -; mRNA.
DR EMBL; AK175483; BAD43246.1; -; mRNA.
DR EMBL; AK221383; BAD94299.1; -; mRNA.
DR PIR; B96808; B96808.
DR RefSeq; NP_974164.2; NM_202435.2. [Q6NQB7-2]
DR AlphaFoldDB; Q6NQB7; -.
DR SMR; Q6NQB7; -.
DR STRING; 3702.AT1G77810.1; -.
DR CAZy; GT31; Glycosyltransferase Family 31.
DR PaxDb; Q6NQB7; -.
DR PeptideAtlas; Q6NQB7; -.
DR PRIDE; Q6NQB7; -.
DR EnsemblPlants; AT1G77810.2; AT1G77810.2; AT1G77810. [Q6NQB7-2]
DR GeneID; 844443; -.
DR Gramene; AT1G77810.2; AT1G77810.2; AT1G77810. [Q6NQB7-2]
DR KEGG; ath:AT1G77810; -.
DR Araport; AT1G77810; -.
DR TAIR; locus:2029471; AT1G77810.
DR eggNOG; KOG2288; Eukaryota.
DR InParanoid; Q6NQB7; -.
DR OMA; WWSPTES; -.
DR PhylomeDB; Q6NQB7; -.
DR UniPathway; UPA00378; -.
DR PRO; PR:Q6NQB7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q6NQB7; baseline and differential.
DR Genevisible; Q6NQB7; AT.
DR GO; GO:0005794; C:Golgi apparatus; IDA:TAIR.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0048531; F:beta-1,3-galactosyltransferase activity; IDA:TAIR.
DR GO; GO:0008378; F:galactosyltransferase activity; IBA:GO_Central.
DR GO; GO:0016757; F:glycosyltransferase activity; IBA:GO_Central.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IBA:GO_Central.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR InterPro; IPR025298; DUF4094.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214; PTHR11214; 1.
DR Pfam; PF13334; DUF4094; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycosyltransferase; Golgi apparatus; Manganese;
KW Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..393
FT /note="Beta-1,3-galactosyltransferase 7"
FT /id="PRO_0000359417"
FT TRANSMEM 9..29
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT REGION 89..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 86..88
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036146"
FT VAR_SEQ 260..266
FT /note="NLLNCFR -> K (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036147"
SQ SEQUENCE 393 AA; 44675 MW; 0F530626D3DE7D2C CRC64;
MKHKVSKRVI SLKWVPFLCI SFFALGAIFT SRSWEPSSDS GSQLISQHHR DHELQIVSDD
CAHNKKATQE KDVTGEVLRT HEAIQDDRSL DKSVSTLSST RSSQEMVDGS ETNPRKKVFM
VMGINTAFSS RKRRDSVRET WMPQGEKLER LEQEKGIVIK FMIGHSATSN SILDRAIDSE
DAQHKDFLRL EHVEGYHELS AKTKIFFSTA VAKWDAEFYI KVDDDVHVNL GMLASTLARH
RSKPRVYIGC MKSGPVLAQN LLNCFRTVKY HEPEYWKFGE DGNKYFRHAT GQIYAISKDL
ANYISINQPI LHKYANEDVS LGSWFIGLEV EHIDDRNFCC GTPPDCRWKA EAGDVCVASF
EWSCSGICKS VERMKIVHEV CSEGEGAVWN TLL
