ID   B3GTC_ARATH             Reviewed;         371 AA.
AC   Q66GS2; O80987;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Probable beta-1,3-galactosyltransferase 12;
DE            EC=2.4.1.-;
GN   Name=B3GALT12; OrderedLocusNames=At2g26100; ORFNames=T19L18.9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18548197; DOI=10.1007/s11103-008-9351-3;
RA   Qu Y., Egelund J., Gilson P.R., Houghton F., Gleeson P.A., Schultz C.J.,
RA   Bacic A.;
RT   "Identification of a novel group of putative Arabidopsis thaliana beta-
RT   (1,3)-galactosyltransferases.";
RL   Plant Mol. Biol. 68:43-59(2008).
CC   -!- FUNCTION: Beta-1,3-galactosyltransferase that transfers galactose from
CC       UDP-galactose to substrates with a terminal glycosyl residue.
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-
CC       pass type II membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC31227.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC004747; AAC31227.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC07794.1; -; Genomic_DNA.
DR   EMBL; BT015330; AAU05453.1; -; mRNA.
DR   EMBL; BT015706; AAU45204.1; -; mRNA.
DR   PIR; T02614; T02614.
DR   RefSeq; NP_180179.2; NM_128168.5.
DR   AlphaFoldDB; Q66GS2; -.
DR   SMR; Q66GS2; -.
DR   STRING; 3702.AT2G26100.1; -.
DR   CAZy; GT31; Glycosyltransferase Family 31.
DR   PaxDb; Q66GS2; -.
DR   PRIDE; Q66GS2; -.
DR   ProteomicsDB; 240960; -.
DR   EnsemblPlants; AT2G26100.1; AT2G26100.1; AT2G26100.
DR   GeneID; 817150; -.
DR   Gramene; AT2G26100.1; AT2G26100.1; AT2G26100.
DR   KEGG; ath:AT2G26100; -.
DR   Araport; AT2G26100; -.
DR   TAIR; locus:2057442; AT2G26100.
DR   eggNOG; KOG2288; Eukaryota.
DR   HOGENOM; CLU_040730_0_0_1; -.
DR   InParanoid; Q66GS2; -.
DR   OMA; KIDMCSK; -.
DR   OrthoDB; 1037602at2759; -.
DR   PhylomeDB; Q66GS2; -.
DR   UniPathway; UPA00378; -.
DR   PRO; PR:Q66GS2; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q66GS2; baseline and differential.
DR   GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR   GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008378; F:galactosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0016757; F:glycosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002659; Glyco_trans_31.
DR   PANTHER; PTHR11214; PTHR11214; 1.
DR   Pfam; PF01762; Galactosyl_T; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Golgi apparatus; Manganese; Membrane;
KW   Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..371
FT                   /note="Probable beta-1,3-galactosyltransferase 12"
FT                   /id="PRO_0000359422"
FT   TRANSMEM        46..66
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        291
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   371 AA;  41217 MW;  17AAC6970A735D6E CRC64;
     MPLFSHRFTT ASSSSPASPS YYNKPSSKTH KPNSSSSSYT SSRIHVAIIF FSLVSVFIGV
     AGTIFALSST GPASVYRCGG SKDTSRVVSA SRKLGGDGGN NGVVVERRKL LGFVGIQTGF
     DSGDRRTALR STWFPSDPDS LLRLEQATGL AFRFVIGKSK DAKKMAELEK EIKEYRDFVL
     LDTEEEYIRL PYKTLAFFKA AFKLFEADYY VKADDDIYLR PDRLATLLAN ERLHSQTYIG
     CMKKGPVITD PKLKWYEKQG NLIGNEYFLH AYGPIYVLSA EIVASLAAAR NGSLRMFNNE
     DVTIGSWMLA MDVHHEDNRA LCDPHCSPKS IAVWDIPKCS GLCDPESRLK ELHKTDMCSK
     SPTLPPDDID Q