ID   RS1_LEULA               Reviewed;         429 AA.
AC   P50889; P71450;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=30S ribosomal protein S1;
GN   Name=rps1;
OS   Leuconostoc lactis.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Leuconostoc.
OX   NCBI_TaxID=1246;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9034319; DOI=10.1016/s0378-1119(96)00636-1;
RA   Yamit-Hezi A., Levy Z., Neuman S., Nudel U.;
RT   "A Leuconostoc lactis protein with homology to ribosomal protein S1 shares
RT   common epitopes and common DNA binding properties with a mammalian DNA
RT   binding nuclear factor.";
RL   Gene 185:99-103(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 24-429.
RX   PubMed=7721096; DOI=10.1016/0378-1119(94)00898-3;
RA   Eklund E.A., Lee S.W., Skalnik D.G.;
RT   "Cloning of a cDNA encoding a human DNA-binding protein similar to
RT   ribosomal protein S1.";
RL   Gene 155:231-235(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 78-429.
RX   PubMed=8568274;
RA   Tsuzaka K., Leu A.K., Frank M.B., Movafagh B.F., Koscec M., Winkler T.H.,
RA   Kalden J.R., Reichlin M.;
RT   "Lupus autoantibodies to double-stranded DNA cross-react with ribosomal
RT   protein S1.";
RL   J. Immunol. 156:1668-1675(1996).
CC   -!- FUNCTION: Binds mRNA; thus facilitating recognition of the initiation
CC       point. It is needed to translate mRNA with a short Shine-Dalgarno (SD)
CC       purine-rich sequence (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS1 family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Was originally (PubMed:7721096 and PubMed:8568274) thought to
CC       originate from human but is most probably the result of a cDNA library
CC       contamination by L.lactis. {ECO:0000305}.
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DR   EMBL; U24086; AAB08978.1; -; Genomic_DNA.
DR   EMBL; U05589; AAA77669.1; -; mRNA.
DR   EMBL; U27517; AAA97575.1; -; mRNA.
DR   AlphaFoldDB; P50889; -.
DR   STRING; 1246.JMEA01000003_gene977; -.
DR   eggNOG; COG0539; Bacteria.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.50.140; -; 4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR035104; Ribosomal_protein_S1-like.
DR   InterPro; IPR022967; S1_dom.
DR   InterPro; IPR003029; S1_domain.
DR   PANTHER; PTHR10724:SF7; PTHR10724:SF7; 2.
DR   Pfam; PF00575; S1; 4.
DR   PRINTS; PR00681; RIBOSOMALS1.
DR   SMART; SM00316; S1; 4.
DR   SUPFAM; SSF50249; SSF50249; 4.
DR   PROSITE; PS50126; S1; 4.
PE   2: Evidence at transcript level;
KW   Repeat; Ribonucleoprotein; Ribosomal protein; RNA-binding.
FT   CHAIN           1..429
FT                   /note="30S ribosomal protein S1"
FT                   /id="PRO_0000196040"
FT   DOMAIN          55..128
FT                   /note="S1 motif 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          144..211
FT                   /note="S1 motif 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          231..299
FT                   /note="S1 motif 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          316..385
FT                   /note="S1 motif 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   REGION          382..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        382..402
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        24
FT                   /note="S -> G (in Ref. 2; AAA77669)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        122
FT                   /note="A -> S (in Ref. 3; AAA97575)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        217
FT                   /note="L -> R (in Ref. 2 and 3)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   429 AA;  46386 MW;  92AC82605F39DDFC CRC64;
     MAHALKRILY ATWYPDILVN YTHSVNCRRT LDVMSETNNE FLAALESAAD QIKVGDVVTG
     ELLAIDNDNQ AVVGLSTGEE GVVPAREYSD DRNINLADEL KIGDTIEAVV ISNVTSDKEG
     VAYLLSKKRL DARKAWENLS FAEGDTVDAK VINAVRGGLI VDVNGVRGFV PASMVAERFV
     SDLNQFKNKD IKAQVIEIDP ANARLILSRK AVAAQELAAQ LAEVFSKLSV GEVVEGTVAR
     LTDFGAFVDL GGVDGLVHVS EISHDRVKNP ADVLTKGDKV DVKILALDTE KGRISLSIKA
     TQRGPWDEAA DQIAAGSVLE GTVKRVKDFG AFVEILPGIE GLVHVSQISN KRIENPSEVL
     KSGDKVQVKV LDIKPAEERI SLSMKALEEK PEREDRRGND GSASRADIAA YKQQDDSAAT
     LGDIFGDKL