ID   RS1_NEIMB               Reviewed;         561 AA.
AC   Q9JZ44;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=30S ribosomal protein S1;
GN   Name=rpsA; OrderedLocusNames=NMB1301;
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58;
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA   Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA   Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=NZ98/254 / Serogroup B;
RX   PubMed=16645985; DOI=10.1002/pmic.200500821;
RA   Vipond C., Suker J., Jones C., Tang C., Feavers I.M., Wheeler J.X.;
RT   "Proteomic analysis of a meningococcal outer membrane vesicle vaccine
RT   prepared from the group B strain NZ98/254.";
RL   Proteomics 6:3400-3413(2006).
CC   -!- FUNCTION: Binds mRNA; thus facilitating recognition of the initiation
CC       point. It is needed to translate mRNA with a short Shine-Dalgarno (SD)
CC       purine-rich sequence (By similarity). {ECO:0000250}.
CC   -!- MISCELLANEOUS: Present in outer membrane vesicle formulations which are
CC       used as vaccines in human.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS1 family.
CC       {ECO:0000305}.
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DR   EMBL; AE002098; AAF41676.1; -; Genomic_DNA.
DR   PIR; G81099; G81099.
DR   RefSeq; NP_274320.1; NC_003112.2.
DR   RefSeq; WP_002237993.1; NC_003112.2.
DR   AlphaFoldDB; Q9JZ44; -.
DR   SMR; Q9JZ44; -.
DR   STRING; 122586.NMB1301; -.
DR   PaxDb; Q9JZ44; -.
DR   PRIDE; Q9JZ44; -.
DR   EnsemblBacteria; AAF41676; AAF41676; NMB1301.
DR   KEGG; nme:NMB1301; -.
DR   PATRIC; fig|122586.8.peg.1633; -.
DR   HOGENOM; CLU_015805_2_1_4; -.
DR   OMA; SLNEFRY; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   Gene3D; 2.40.50.140; -; 6.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR035104; Ribosomal_protein_S1-like.
DR   InterPro; IPR000110; Ribosomal_S1.
DR   InterPro; IPR022967; S1_dom.
DR   InterPro; IPR003029; S1_domain.
DR   PANTHER; PTHR10724:SF7; PTHR10724:SF7; 2.
DR   Pfam; PF00575; S1; 6.
DR   PIRSF; PIRSF002111; RpsA; 1.
DR   PRINTS; PR00681; RIBOSOMALS1.
DR   SMART; SM00316; S1; 6.
DR   SUPFAM; SSF50249; SSF50249; 6.
DR   TIGRFAMs; TIGR00717; rpsA; 1.
DR   PROSITE; PS50126; S1; 6.
PE   1: Evidence at protein level;
KW   Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding.
FT   CHAIN           1..561
FT                   /note="30S ribosomal protein S1"
FT                   /id="PRO_0000320264"
FT   DOMAIN          22..88
FT                   /note="S1 motif 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          106..172
FT                   /note="S1 motif 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          193..261
FT                   /note="S1 motif 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          278..348
FT                   /note="S1 motif 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          365..435
FT                   /note="S1 motif 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT   DOMAIN          452..521
FT                   /note="S1 motif 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
SQ   SEQUENCE   561 AA;  61177 MW;  2CF6FD8DD99D1615 CRC64;
     MSMENFAQLL EESFTLQEMN PGEVITAEVV AIDQNFVTVN AGLKSESLID VAEFKNAQGE
     IEVKVGDFVT VTIESVENGF GETKLSREKA KRAADWIALE EAMENGDILS GIINGKVKGG
     LTVMISSIRA FLPGSLVDVR PVKDTSHFEG KEIEFKVIKL DKKRNNVVVS RRAVLEATLG
     EERKALLENL QEGSVIKGIV KNITDYGAFV DLGGIDGLLH ITDLAWRRVK HPSEVLEVGQ
     EVEAKVLKFD QEKQRVSLGM KQLGEDPWSG LTRRYPQGTR LFGKVSNLTD YGAFVEIEQG
     IEGLVHVSEM DWTNKNVHPS KVVQLGDEVE VMILEIDEGR RRISLGMKQC QANPWEEFAA
     NHNKGDKISG AVKSITDFGV FVGLPGGIDG LVHLSDLSWT ESGEEAVRKY KKGEEVEAVV
     LAIDVEKERI SLGIKQLEGD PFGNFISVND KGSLVKGSVK SVDAKGAVIA LSDEVEGYLP
     ASEFAADRVE DLTTKLKEGD EVEAVIVTVD RKNRSIKLSV KAKDAKESRE ALNSVNAAAN
     ANAGTTSLGD LLKAKLSGEQ E