RS1_STRR6
ID RS1_STRR6 Reviewed; 400 AA.
AC Q8CWR9;
DT 11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=30S Ribosomal protein S1;
GN Name=rpsA; OrderedLocusNames=spr0764;
OS Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=171101;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-255 / R6;
RX PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL J. Bacteriol. 183:5709-5717(2001).
RN [2]
RP PHOSPHORYLATION, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=15720398; DOI=10.1111/j.1742-4658.2005.04560.x;
RA Novakova L., Saskova L., Pallova P., Janecek J., Novotna J., Ulrych A.,
RA Echenique J., Trombe M.C., Branny P.;
RT "Characterization of a eukaryotic type serine/threonine protein kinase and
RT protein phosphatase of Streptococcus pneumoniae and identification of
RT kinase substrates.";
RL FEBS J. 272:1243-1254(2005).
CC -!- FUNCTION: Binds mRNA; thus facilitating recognition of the initiation
CC point. It is needed to translate mRNA with a short Shine-Dalgarno (SD)
CC purine-rich sequence (By similarity). {ECO:0000250}.
CC -!- PTM: Phosphorylated. {ECO:0000269|PubMed:15720398}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS1 family.
CC {ECO:0000305}.
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DR EMBL; AE007317; AAK99568.1; -; Genomic_DNA.
DR PIR; D97967; D97967.
DR RefSeq; NP_358358.1; NC_003098.1.
DR RefSeq; WP_001001623.1; NC_003098.1.
DR AlphaFoldDB; Q8CWR9; -.
DR STRING; 171101.spr0764; -.
DR PRIDE; Q8CWR9; -.
DR EnsemblBacteria; AAK99568; AAK99568; spr0764.
DR GeneID; 60232794; -.
DR GeneID; 66805998; -.
DR KEGG; spr:spr0764; -.
DR PATRIC; fig|171101.6.peg.846; -.
DR eggNOG; COG0539; Bacteria.
DR HOGENOM; CLU_015805_4_5_9; -.
DR OMA; WQQFART; -.
DR PRO; PR:Q8CWR9; -.
DR Proteomes; UP000000586; Chromosome.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR Gene3D; 2.40.50.140; -; 4.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR035104; Ribosomal_protein_S1-like.
DR InterPro; IPR022967; S1_dom.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR10724:SF7; PTHR10724:SF7; 1.
DR Pfam; PF00575; S1; 4.
DR PRINTS; PR00681; RIBOSOMALS1.
DR SMART; SM00316; S1; 4.
DR SUPFAM; SSF50249; SSF50249; 4.
DR PROSITE; PS50126; S1; 4.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding.
FT CHAIN 1..400
FT /note="30S Ribosomal protein S1"
FT /id="PRO_0000418150"
FT DOMAIN 17..87
FT /note="S1 motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 107..173
FT /note="S1 motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 194..262
FT /note="S1 motif 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 279..348
FT /note="S1 motif 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT REGION 351..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 43896 MW; 03890FEB86C5EA14 CRC64;
MNEFEDLLNS VSQVETGDVV SAEVLTVDAT QANVAISGTG VEGVLTLREL TNDRDADIND
FVKVGEVLDV LVLRQVVGKD TDTVTYLVSK KRLEARKAWD KLVGREEEVV TVKGTRAVKG
GLSVEFEGVR GFIPASMLDT RFVRNAERFV GQEFDTKIKE VNAKENRFIL SRREVVEAAT
AAARAEVFGK LAVGDVVTGK VARITSFGAF IDLGGVDGLV HLTELSHERN VSPKSVVTVG
EEIEVKILDL NEEEGRVSLS LKATVPGPWD GVEQKLAKGD VVEGTVKRLT DFGAFVEVLP
GIDGLVHVSQ ISHKRIENPK EALKVGQEVQ VKVLEVNADA ERVSLSIKAL EERPAQEEGQ
KEEKRAARPR RPRRQEKRDF ELPETQTGFS MADLFGDIEL
