ID   B4_VACCC                Reviewed;         558 AA.
AC   P21001;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Ankyrin repeat protein B4;
GN   ORFNames=B4R;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- SIMILARITY: Belongs to the poxviridae B4 protein family. {ECO:0000305}.
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DR   EMBL; M35027; AAA48200.1; -; Genomic_DNA.
DR   PIR; C42526; C42526.
DR   SMR; P21001; -.
DR   PRIDE; P21001; -.
DR   Proteomes; UP000008269; Genome.
DR   Gene3D; 1.25.40.20; -; 3.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR018272; PRANC_domain.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF09372; PRANC; 1.
DR   SMART; SM00248; ANK; 7.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat; Late protein; Reference proteome; Repeat.
FT   CHAIN           1..558
FT                   /note="Ankyrin repeat protein B4"
FT                   /id="PRO_0000067084"
FT   REPEAT          65..95
FT                   /note="ANK 1"
FT   REPEAT          169..205
FT                   /note="ANK 2"
FT   REPEAT          209..239
FT                   /note="ANK 3"
FT   REPEAT          243..272
FT                   /note="ANK 4"
FT   REPEAT          276..304
FT                   /note="ANK 5"
FT   REPEAT          339..368
FT                   /note="ANK 6"
FT   REPEAT          372..401
FT                   /note="ANK 7"
SQ   SEQUENCE   558 AA;  65272 MW;  ED672F454DB7FC76 CRC64;
     MDFFKKEILD WSVYLSLHYI ARVCSNSSTS HIIQDYNLIR TYEKVDKTIV DFLSRLPNLF
     HILEYGENIL HIYSMDDANT NIIIFFLDRV LNINKNGSFI HNLRLSSSIN IKEYVYQLVN
     NDHPDNRIRL MLENGRRTRH FLSYISDTVN IYICILINHG FYIDAEDSYG CTLLHRCIYH
     YKKSESESYN ELIKILLNNG SDVDKKDTYG NTPFILLCKH DINNVELFEI CLENANIDSV
     DFNRYTPLHY VSCRNKYDFV KLLISKGANV NARNKFGTTP FYCGIIHGIS LIKLYLESDT
     ELEIDNEHIV RHLIIFDAVE SLDYLLSRGV IDINYRTIYN ETSIYDAVSY NAYNTLVYLL
     NRNGDFETIT TSGCTCISEA VANNNKIIME VLLSKRPSLK IMIQSMIAIT KNKQHNADLL
     KMCIKYTACM TDYDTLIDVQ SLQQYKWYIL KCFDEIDIMK RCYIKNKTVF QLVFCIKDIN
     TLMRYGKHPS FVKCTSLDVY GSRVRNIIAS IRYRQRLISL LSKKLDAGDK WSCFPNEIKY
     KILENFNDNE LSTYLKIL