ID   B4_VACCW                Reviewed;         558 AA.
AC   P24769; Q76ZL9;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   23-FEB-2022, entry version 83.
DE   RecName: Full=Ankyrin repeat protein B4;
GN   OrderedLocusNames=VACWR186; ORFNames=B4R;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2045793; DOI=10.1099/0022-1317-72-6-1349;
RA   Smith G.L., Chan Y.S., Howard S.T.;
RT   "Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the
RT   right inverted terminal repeat.";
RL   J. Gen. Virol. 72:1349-1376(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1846491; DOI=10.1016/0042-6822(91)90077-o;
RA   Howard S.T., Chan Y.S., Smith G.L.;
RT   "Vaccinia virus homologues of the Shope fibroma virus inverted terminal
RT   repeat proteins and a discontinuous ORF related to the tumor necrosis
RT   factor receptor family.";
RL   Virology 180:633-647(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the poxviridae B4 protein family. {ECO:0000305}.
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DR   EMBL; D11079; BAA01834.1; -; Genomic_DNA.
DR   EMBL; M58055; AAA47965.1; -; Genomic_DNA.
DR   EMBL; AY243312; AAO89465.1; -; Genomic_DNA.
DR   PIR; JQ1798; JQ1798.
DR   RefSeq; YP_233068.1; NC_006998.1.
DR   SMR; P24769; -.
DR   DNASU; 3707657; -.
DR   GeneID; 3707657; -.
DR   KEGG; vg:3707657; -.
DR   Proteomes; UP000000344; Genome.
DR   Gene3D; 1.25.40.20; -; 3.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR018272; PRANC_domain.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF09372; PRANC; 1.
DR   SMART; SM00248; ANK; 7.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat; Late protein; Reference proteome; Repeat.
FT   CHAIN           1..558
FT                   /note="Ankyrin repeat protein B4"
FT                   /id="PRO_0000067085"
FT   REPEAT          65..95
FT                   /note="ANK 1"
FT   REPEAT          169..205
FT                   /note="ANK 2"
FT   REPEAT          209..239
FT                   /note="ANK 3"
FT   REPEAT          243..272
FT                   /note="ANK 4"
FT   REPEAT          276..304
FT                   /note="ANK 5"
FT   REPEAT          339..368
FT                   /note="ANK 6"
FT   REPEAT          372..401
FT                   /note="ANK 7"
SQ   SEQUENCE   558 AA;  65453 MW;  10089DF5BFB1ABF0 CRC64;
     MDFFKKEILD WSIYLSLHYI ARVFSNFSTS HIIQDYNLVR TYEKVDKTIV DFLSRLPNLF
     HILEYGENIL HIYSMDDANT NIIIFFLDRV LNINKNGSFI HNLRLSSSIN IKEYVYQLVN
     NDHPDNRIRL MLENGRRTRH FLSYISDTVN IYICILINHG FYIDAEDSYG CTLLHRCIYH
     YKKSESESYN ELIKILLNNG SDVDKKDTYG NTPFILLCKH DINNVELFEI CLENANIDSV
     DFNRYTPLHY VSCRNKYDFV KLLISKGANV NARNRFGTTP FYCGIIHGIS LIKLYLESDT
     ELEIDNEHIV RHLIIFDAVE SLDYLLSRGV IDINYRTIYN ETSIYDAVSY NAYNTLVYLL
     NRNGDFETIT TSGCTCISEA VANNNKIIME VLLSKRPSLK IMIQSMIAIT KHKQHNADLL
     KMCIKYTACM TDYDTLIDVQ SLQQYKWYIL KCFDEIDIMK RCYIKNKTVF QLVFCIKDIN
     TLMRYGKHPS FVKCTSLDVY GSRVRNIIAS IRYRQRLISL LSKKLDPGDK WSCFPNEIKY
     KILENFNDNE LSTYLKIL