ID   B7_USTMD                Reviewed;         410 AA.
AC   P22021;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Mating-type locus allele B7 protein;
OS   Ustilago maydis (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=5270;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 22891 / 43;
RX   PubMed=2227416; DOI=10.1101/gad.4.8.1384;
RA   Kronstad J.W., Leong S.A.;
RT   "The b mating-type locus of Ustilago maydis contains variable and constant
RT   regions.";
RL   Genes Dev. 4:1384-1395(1990).
CC   -!- FUNCTION: The B locus has at least 25 alleles, and any combination of
CC       two different B alleles yields a multimeric regulatory protein, that
CC       activates genes responsible for the pathogenicity and for the sexual
CC       development of the fungus within the corn plant.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family. {ECO:0000305}.
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DR   EMBL; X53903; CAA37871.1; -; Genomic_DNA.
DR   EMBL; X54070; CAA38001.1; -; Genomic_DNA.
DR   PIR; F36671; F36671.
DR   PIR; S21297; S21297.
DR   AlphaFoldDB; P22021; -.
DR   VEuPathDB; FungiDB:UMAG_12052; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR008888; Ustilago_mating.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF05722; Ustilago_mating; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Homeobox; Nucleus.
FT   CHAIN           1..410
FT                   /note="Mating-type locus allele B7 protein"
FT                   /id="PRO_0000049407"
FT   DNA_BIND        107..184
FT                   /note="Homeobox; TALE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          1..110
FT                   /note="Variable domain between B alleles"
FT   REGION          111..410
FT                   /note="Highly conserved between B alleles"
FT   REGION          202..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..336
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          333..410
FT                   /note="Not essential for B7 function"
FT   REGION          374..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           276..308
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        304..336
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   410 AA;  45764 MW;  76AC0E36AA8ACDC8 CRC64;
     MSSDPNFSLT SFLECLSQIE HEFLRDKVEN PPVLVRKLQE LQQKTPGHVA SLLHDPETIQ
     QIHQTAHRIE VAVKVFIHID QKFTSGCSEV VHGTSKVMQE VNVGSPAVGC RNLSEDLPAY
     HMRKHFLLTL DSPYPTQEEK EGLVRLTNES TARVGLSNAT RPPLEVHQLT LWFINARRRS
     GWSHILKKFA REDRSRMKRL VRAKLSSSTQ SSPPSPMPEY PSNNLDNILS DNLGRPLTPA
     DKQQFEDDWA SMISWIKYGV KEKVGDWVYD LCAASKKTPK PGMPRPVTTV AKRQPARKTK
     PAAKPNSRTA NPRASTTPSI DSTLDSSKLE STPELSMCST ADTSFSTFGS SLSMSHYNPF
     QDGNDILQSP TVKARGNRKV KALPKRAGKQ QPDEVENGKI PFLCLSVAFV