B9D2_BOVIN
ID B9D2_BOVIN Reviewed; 175 AA.
AC Q56JY9;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=B9 domain-containing protein 2;
GN Name=B9D2;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lymphoid epithelium;
RA Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.;
RT "Analysis of sequences obtained from constructed full-length bovine cDNA
RT libraries.";
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the tectonic-like complex, a complex localized
CC at the transition zone of primary cilia and acting as a barrier that
CC prevents diffusion of transmembrane proteins between the cilia and
CC plasma membranes. {ECO:0000250}.
CC -!- SUBUNIT: Part of the tectonic-like complex (also named B9 complex).
CC Interacts with TUBG1 (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC {ECO:0000250}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}.
CC Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the B9D family. {ECO:0000305}.
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DR EMBL; AY911338; AAW82106.1; -; mRNA.
DR RefSeq; NP_001035683.1; NM_001040593.2.
DR AlphaFoldDB; Q56JY9; -.
DR STRING; 9913.ENSBTAP00000031913; -.
DR PaxDb; Q56JY9; -.
DR PRIDE; Q56JY9; -.
DR GeneID; 616609; -.
DR KEGG; bta:616609; -.
DR CTD; 80776; -.
DR eggNOG; KOG4028; Eukaryota.
DR InParanoid; Q56JY9; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0036064; C:ciliary basal body; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0036038; C:MKS complex; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.
DR GO; GO:0060271; P:cilium assembly; ISS:UniProtKB.
DR InterPro; IPR010796; C2_B9-type_dom.
DR PANTHER; PTHR12968; PTHR12968; 1.
DR Pfam; PF07162; B9-C2; 1.
DR PROSITE; PS51381; C2_B9; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cilium; Cilium biogenesis/degradation; Cytoplasm;
KW Cytoskeleton; Nucleus; Reference proteome.
FT CHAIN 1..175
FT /note="B9 domain-containing protein 2"
FT /id="PRO_0000307673"
FT DOMAIN 2..118
FT /note="C2 B9-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00713"
SQ SEQUENCE 175 AA; 19358 MW; 23E041118EE6B246 CRC64;
MAEVHVIGQI MGATGFSESS LFCKWGVHTG AAWKLLSGVR EGQTQVDTPQ IGDMAYWSHP
IDLHFATKGL QGWPRLHLQV WSQDSFGRCQ LAGYGFCHVP SSPGTHQLDC PTWRPLGSWR
EQLARAFVGG GPQLLHGDAI YSGADRYRLH TTSGGTVHLE LSLLLRHFDR YGVEC