ID   RS21_BOVIN              Reviewed;          83 AA.
AC   Q32PB8;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=40S ribosomal protein S21;
GN   Name=RPS21;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the 40S small ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P63220}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P63220}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P63220}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:P63221}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:P63220, ECO:0000250|UniProtKB:P63221}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS21 family.
CC       {ECO:0000305}.
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DR   EMBL; BC108180; AAI08181.1; -; mRNA.
DR   RefSeq; NP_001035671.1; NM_001040581.2.
DR   RefSeq; XP_005214907.1; XM_005214850.1.
DR   RefSeq; XP_010809831.1; XM_010811529.1.
DR   AlphaFoldDB; Q32PB8; -.
DR   SMR; Q32PB8; -.
DR   STRING; 9913.ENSBTAP00000027713; -.
DR   PaxDb; Q32PB8; -.
DR   PeptideAtlas; Q32PB8; -.
DR   PRIDE; Q32PB8; -.
DR   Ensembl; ENSBTAT00000027713; ENSBTAP00000027713; ENSBTAG00000020795.
DR   GeneID; 615178; -.
DR   KEGG; bta:615178; -.
DR   CTD; 6227; -.
DR   VEuPathDB; HostDB:ENSBTAG00000020795; -.
DR   VGNC; VGNC:34134; RPS21.
DR   eggNOG; KOG3486; Eukaryota.
DR   GeneTree; ENSGT00390000017515; -.
DR   HOGENOM; CLU_167122_2_0_1; -.
DR   InParanoid; Q32PB8; -.
DR   OMA; ALCGYIR; -.
DR   OrthoDB; 1571849at2759; -.
DR   TreeFam; TF300167; -.
DR   Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-BTA-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000009136; Chromosome 13.
DR   Bgee; ENSBTAG00000020795; Expressed in ileocecal valve and 109 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0045202; C:synapse; IEA:Ensembl.
DR   GO; GO:0047485; F:protein N-terminus binding; IEA:Ensembl.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   Gene3D; 3.30.1230.20; -; 1.
DR   InterPro; IPR001931; Ribosomal_S21e.
DR   InterPro; IPR018279; Ribosomal_S21e_CS.
DR   InterPro; IPR038579; Ribosomal_S21e_sf.
DR   PANTHER; PTHR10442; PTHR10442; 1.
DR   Pfam; PF01249; Ribosomal_S21e; 1.
DR   PIRSF; PIRSF002148; Ribosomal_S21e; 1.
DR   PROSITE; PS00996; RIBOSOMAL_S21E; 1.
PE   3: Inferred from homology;
KW   Acetylation; Cytoplasm; Endoplasmic reticulum; Isopeptide bond;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation.
FT   CHAIN           1..83
FT                   /note="40S ribosomal protein S21"
FT                   /id="PRO_0000240298"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:P63220"
FT   MOD_RES         81
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P63220"
FT   CROSSLNK        41
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:P63220"
SQ   SEQUENCE   83 AA;  9111 MW;  6794AC1292A06BD3 CRC64;
     MQNDAGEFVD LYVPRKCSAS NRIIGAKDHA SIQMNVAEVD KVTGRFNGQF KTYAICGAIR
     RMGESDDSIL RLAKADGIVS KNF