ID   RS21_CAEEL              Reviewed;          88 AA.
AC   P49197;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=40S ribosomal protein S21;
GN   Name=rps-21; ORFNames=F37C12.11;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBUNIT: Component of the 40S small ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P63220}.
CC   -!- INTERACTION:
CC       P49197; P46769: rps-0; NbExp=4; IntAct=EBI-313268, EBI-313262;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P63220}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P63220}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:P63221}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:P63220, ECO:0000250|UniProtKB:P63221}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS21 family.
CC       {ECO:0000305}.
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DR   EMBL; FO081316; CCD70740.1; -; Genomic_DNA.
DR   PIR; T28840; T28840.
DR   RefSeq; NP_498579.2; NM_066178.6.
DR   AlphaFoldDB; P49197; -.
DR   SMR; P49197; -.
DR   BioGRID; 41223; 103.
DR   DIP; DIP-25541N; -.
DR   IntAct; P49197; 1.
DR   STRING; 6239.F37C12.11; -.
DR   EPD; P49197; -.
DR   PaxDb; P49197; -.
DR   PeptideAtlas; P49197; -.
DR   EnsemblMetazoa; F37C12.11.1; F37C12.11.1; WBGene00004490.
DR   GeneID; 176011; -.
DR   KEGG; cel:CELE_F37C12.11; -.
DR   UCSC; F37C12.11.1; c. elegans.
DR   CTD; 176011; -.
DR   WormBase; F37C12.11; CE30779; WBGene00004490; rps-21.
DR   eggNOG; KOG3486; Eukaryota.
DR   GeneTree; ENSGT00390000017515; -.
DR   HOGENOM; CLU_167122_2_0_1; -.
DR   InParanoid; P49197; -.
DR   OMA; ALCGYIR; -.
DR   OrthoDB; 1571849at2759; -.
DR   PhylomeDB; P49197; -.
DR   Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-CEL-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-CEL-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P49197; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00004490; Expressed in larva and 4 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 3.30.1230.20; -; 1.
DR   InterPro; IPR001931; Ribosomal_S21e.
DR   InterPro; IPR018279; Ribosomal_S21e_CS.
DR   InterPro; IPR038579; Ribosomal_S21e_sf.
DR   PANTHER; PTHR10442; PTHR10442; 1.
DR   Pfam; PF01249; Ribosomal_S21e; 1.
DR   PIRSF; PIRSF002148; Ribosomal_S21e; 1.
DR   PROSITE; PS00996; RIBOSOMAL_S21E; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Endoplasmic reticulum; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..88
FT                   /note="40S ribosomal protein S21"
FT                   /id="PRO_0000194747"
SQ   SEQUENCE   88 AA;  9675 MW;  40FF35E4F56456C7 CRC64;
     MQNDAGQTVE LYVPRKCSSS NRIIGPKDHA SVQIDFVDVD PETGRMIPGK STRYAICGAI
     RRMGESDDAI LRLAQKDGLV PRDDVKSN