ID   RS21_DANRE              Reviewed;          81 AA.
AC   Q7ZUG5;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=40S ribosomal protein S21;
GN   Name=rps21;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the 40S small ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P63220}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P63220}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P63220}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:P63221}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:P63220, ECO:0000250|UniProtKB:P63221}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS21 family.
CC       {ECO:0000305}.
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DR   EMBL; BC049056; AAH49056.1; -; mRNA.
DR   EMBL; BC071475; AAH71475.1; -; mRNA.
DR   RefSeq; NP_957485.1; NM_201191.1.
DR   AlphaFoldDB; Q7ZUG5; -.
DR   SMR; Q7ZUG5; -.
DR   STRING; 7955.ENSDARP00000122013; -.
DR   PaxDb; Q7ZUG5; -.
DR   Ensembl; ENSDART00000033663; ENSDARP00000031181; ENSDARG00000025850.
DR   Ensembl; ENSDART00000139870; ENSDARP00000122013; ENSDARG00000025850.
DR   GeneID; 394166; -.
DR   KEGG; dre:394166; -.
DR   CTD; 6227; -.
DR   ZFIN; ZDB-GENE-040426-1102; rps21.
DR   eggNOG; KOG3486; Eukaryota.
DR   GeneTree; ENSGT00390000017515; -.
DR   HOGENOM; CLU_167122_2_0_1; -.
DR   InParanoid; Q7ZUG5; -.
DR   OMA; ALCGYIR; -.
DR   OrthoDB; 1571849at2759; -.
DR   PhylomeDB; Q7ZUG5; -.
DR   TreeFam; TF300167; -.
DR   Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DRE-72649; Translation initiation complex formation.
DR   Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DRE-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-DRE-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q7ZUG5; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 23.
DR   Bgee; ENSDARG00000025850; Expressed in tail bud paraxial mesoderm and 28 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   Gene3D; 3.30.1230.20; -; 1.
DR   InterPro; IPR001931; Ribosomal_S21e.
DR   InterPro; IPR018279; Ribosomal_S21e_CS.
DR   InterPro; IPR038579; Ribosomal_S21e_sf.
DR   PANTHER; PTHR10442; PTHR10442; 1.
DR   Pfam; PF01249; Ribosomal_S21e; 1.
DR   PIRSF; PIRSF002148; Ribosomal_S21e; 1.
DR   PROSITE; PS00996; RIBOSOMAL_S21E; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Endoplasmic reticulum; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..81
FT                   /note="40S ribosomal protein S21"
FT                   /id="PRO_0000194734"
SQ   SEQUENCE   81 AA;  8902 MW;  36799F8D725B3E10 CRC64;
     MQNDAGEFVD LYVPRKCSAS NRIIGAKDHA SIQINIAEVD RVTGRFNGQF KTYAICGAIR
     RMGEADDSLL RLAKTDSIVA K