RS21_DROWI
ID RS21_DROWI Reviewed; 83 AA.
AC B4N002;
DT 13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 56.
DE RecName: Full=40S ribosomal protein S21 {ECO:0000250|UniProtKB:O76927};
DE AltName: Full=Overgrown hematopoietic organs at 23B {ECO:0000250|UniProtKB:O76927};
GN Name=RpS21; Synonyms=oho23B; ORFNames=GK24281;
OS Drosophila willistoni (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7260;
RN [1] {ECO:0000312|EMBL:EDW77937.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14030-0811.24 {ECO:0000312|EMBL:EDW77937.1};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: May be an associated component of the ribosome rather than a
CC core structural subunit. May act as a translation initiation factor.
CC Has a role in regulation of cell proliferation in the hematopoietic
CC organs and the imaginal disks of larva (By similarity).
CC {ECO:0000250|UniProtKB:O76927}.
CC -!- SUBUNIT: Component of the 40S small ribosomal subunit. Interacts with
CC sta. {ECO:0000250|UniProtKB:O76927}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:P63220}. Cytoplasm
CC {ECO:0000250|UniProtKB:P63220}. Rough endoplasmic reticulum
CC {ECO:0000250|UniProtKB:P63221}. Note=Detected on cytosolic polysomes
CC (By similarity). Detected in ribosomes that are associated with the
CC rough endoplasmic reticulum (By similarity).
CC {ECO:0000250|UniProtKB:P63220, ECO:0000250|UniProtKB:P63221}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS21 family.
CC {ECO:0000255}.
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DR EMBL; CH963920; EDW77937.1; -; Genomic_DNA.
DR RefSeq; XP_002066951.1; XM_002066915.2.
DR AlphaFoldDB; B4N002; -.
DR SMR; B4N002; -.
DR STRING; 7260.FBpp0253424; -.
DR EnsemblMetazoa; FBtr0254932; FBpp0253424; FBgn0226242.
DR GeneID; 6643769; -.
DR KEGG; dwi:6643769; -.
DR eggNOG; KOG3486; Eukaryota.
DR HOGENOM; CLU_167122_2_0_1; -.
DR InParanoid; B4N002; -.
DR OMA; ALCGYIR; -.
DR OrthoDB; 1571849at2759; -.
DR PhylomeDB; B4N002; -.
DR ChiTaRS; RpS21; fly.
DR Proteomes; UP000007798; Unassembled WGS sequence.
DR GO; GO:0022626; C:cytosolic ribosome; IEA:EnsemblMetazoa.
DR GO; GO:0005840; C:ribosome; ISS:UniProtKB.
DR GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:EnsemblMetazoa.
DR GO; GO:0048542; P:lymph gland development; IEA:EnsemblMetazoa.
DR GO; GO:0042127; P:regulation of cell population proliferation; ISS:UniProtKB.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.30.1230.20; -; 1.
DR InterPro; IPR001931; Ribosomal_S21e.
DR InterPro; IPR018279; Ribosomal_S21e_CS.
DR InterPro; IPR038579; Ribosomal_S21e_sf.
DR PANTHER; PTHR10442; PTHR10442; 1.
DR Pfam; PF01249; Ribosomal_S21e; 1.
DR PIRSF; PIRSF002148; Ribosomal_S21e; 1.
DR PROSITE; PS00996; RIBOSOMAL_S21E; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Developmental protein; Endoplasmic reticulum;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; rRNA processing;
KW Translation regulation.
FT CHAIN 1..83
FT /note="40S ribosomal protein S21"
FT /id="PRO_0000395425"
SQ SEQUENCE 83 AA; 9167 MW; DDFB9D498B396E05 CRC64;
MENDAGENVD LYVPRKCSAS NRIIHAKDHA SVQLSIVDVD PETGRQTDGS KTYAICGEIR
RMGESDDCIV RLAKKDGLIT KNF
