ID   RS21_DROYA              Reviewed;          83 AA.
AC   Q6XIR2;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=40S ribosomal protein S21 {ECO:0000250|UniProtKB:O76927};
DE   AltName: Full=Overgrown hematopoietic organs at 23B {ECO:0000250|UniProtKB:O76927};
GN   Name=RpS21; Synonyms=oho23B; ORFNames=GE18186;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1] {ECO:0000312|EMBL:AAR09790.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=14525923; DOI=10.1101/gr.1311003;
RA   Domazet-Loso T., Tautz D.;
RT   "An evolutionary analysis of orphan genes in Drosophila.";
RL   Genome Res. 13:2213-2219(2003).
RN   [2] {ECO:0000312|EMBL:EDW87456.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tai18E2 / Tucson 14021-0261.01 {ECO:0000312|EMBL:EDW87456.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: May be an associated component of the ribosome rather than a
CC       core structural subunit. May act as a translation initiation factor.
CC       Has a role in regulation of cell proliferation in the hematopoietic
CC       organs and the imaginal disks of larva (By similarity).
CC       {ECO:0000250|UniProtKB:O76927}.
CC   -!- SUBUNIT: Component of the 40S small ribosomal subunit. Interacts with
CC       sta. {ECO:0000250|UniProtKB:O76927}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P63220}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P63220}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:P63221}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:P63220, ECO:0000250|UniProtKB:P63221}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS21 family.
CC       {ECO:0000255}.
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DR   EMBL; AY231767; AAR09790.1; -; mRNA.
DR   EMBL; AY231999; AAR10022.1; -; mRNA.
DR   EMBL; CM000157; EDW87456.1; -; Genomic_DNA.
DR   RefSeq; XP_002087744.1; XM_002087708.2.
DR   AlphaFoldDB; Q6XIR2; -.
DR   SMR; Q6XIR2; -.
DR   STRING; 7245.FBpp0263196; -.
DR   EnsemblMetazoa; FBtr0264704; FBpp0263196; FBgn0235617.
DR   GeneID; 6526636; -.
DR   KEGG; dya:Dyak_GE18186; -.
DR   eggNOG; KOG3486; Eukaryota.
DR   HOGENOM; CLU_167122_2_0_1; -.
DR   OMA; ALCGYIR; -.
DR   OrthoDB; 1571849at2759; -.
DR   PhylomeDB; Q6XIR2; -.
DR   ChiTaRS; RpS21; fly.
DR   Proteomes; UP000002282; Chromosome 2L.
DR   GO; GO:0022626; C:cytosolic ribosome; IEA:EnsemblMetazoa.
DR   GO; GO:0005840; C:ribosome; ISS:UniProtKB.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:EnsemblMetazoa.
DR   GO; GO:0048542; P:lymph gland development; IEA:EnsemblMetazoa.
DR   GO; GO:0042127; P:regulation of cell population proliferation; ISS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 3.30.1230.20; -; 1.
DR   InterPro; IPR001931; Ribosomal_S21e.
DR   InterPro; IPR018279; Ribosomal_S21e_CS.
DR   InterPro; IPR038579; Ribosomal_S21e_sf.
DR   PANTHER; PTHR10442; PTHR10442; 1.
DR   Pfam; PF01249; Ribosomal_S21e; 1.
DR   PIRSF; PIRSF002148; Ribosomal_S21e; 1.
DR   PROSITE; PS00996; RIBOSOMAL_S21E; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Developmental protein; Endoplasmic reticulum; Ribonucleoprotein;
KW   Ribosomal protein; rRNA processing; Translation regulation.
FT   CHAIN           1..83
FT                   /note="40S ribosomal protein S21"
FT                   /id="PRO_0000395426"
SQ   SEQUENCE   83 AA;  9167 MW;  DDFB9D498B3E1E05 CRC64;
     MENDAGENVD LYVPRKCSAS NRIIHAKDHA SVQLSIVDVD PETGRQTDGS KTYAICGEIR
     RMGESDDCIV RLAKKDGIIT KNF