ID   BACA_RHIME              Reviewed;         420 AA.
AC   Q08120;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2001, sequence version 2.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Bacteroid development protein BacA;
GN   Name=bacA; OrderedLocusNames=RB1125; ORFNames=SMb20999;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymB (megaplasmid 2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBCELLULAR LOCATION.
RC   STRAIN=1021;
RX   PubMed=8393417; DOI=10.1101/gad.7.8.1485;
RA   Glazebrook J., Ichige A., Walker G.C.;
RT   "A Rhizobium meliloti homolog of the Escherichia coli peptide-antibiotic
RT   transport protein SbmA is essential for bacteroid development.";
RL   Genes Dev. 7:1485-1497(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481431; DOI=10.1073/pnas.161294698;
RA   Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J.,
RA   Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
RT   "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing
RT   endosymbiont Sinorhizobium meliloti.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Functions in the transport of molecules, possibly peptides,
CC       across the inner membrane. Is essential for bacteroid development.
CC       {ECO:0000269|PubMed:8393417}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305|PubMed:8393417};
CC       Multi-pass membrane protein {ECO:0000305|PubMed:8393417}.
CC   -!- SIMILARITY: Belongs to the peptide uptake permease (PUP) (TC 9.A.18)
CC       family. {ECO:0000305}.
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DR   EMBL; X73522; CAA51918.1; -; Genomic_DNA.
DR   EMBL; AL591985; CAC49525.1; -; Genomic_DNA.
DR   PIR; A47649; A47649.
DR   PIR; E95982; E95982.
DR   RefSeq; NP_437665.1; NC_003078.1.
DR   RefSeq; WP_010975957.1; NC_003078.1.
DR   AlphaFoldDB; Q08120; -.
DR   SMR; Q08120; -.
DR   STRING; 266834.SM_b20999; -.
DR   TCDB; 9.A.18.1.2; the peptide uptake permease (pup) family.
DR   EnsemblBacteria; CAC49525; CAC49525; SM_b20999.
DR   GeneID; 61601077; -.
DR   KEGG; sme:SM_b20999; -.
DR   PATRIC; fig|266834.11.peg.6054; -.
DR   eggNOG; COG1133; Bacteria.
DR   HOGENOM; CLU_045533_0_0_5; -.
DR   OMA; TSHYIFR; -.
DR   Proteomes; UP000001976; Plasmid pSymB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:1904680; F:peptide transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015833; P:peptide transport; IEA:InterPro.
DR   InterPro; IPR036640; ABC1_TM_sf.
DR   InterPro; IPR009248; SbmA_BacA.
DR   Pfam; PF05992; SbmA_BacA; 1.
DR   SUPFAM; SSF90123; SSF90123; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Plasmid; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..420
FT                   /note="Bacteroid development protein BacA"
FT                   /id="PRO_0000064798"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        336..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        128
FT                   /note="A -> P (in Ref. 1; CAA51918)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   420 AA;  47849 MW;  548496A86AD1D0FE CRC64;
     MFQSFFPKPK LFFISSAVWS LLAVLAWYAG GRDIGAYLGL PPLPPGQEPV IGVSVFWSTP
     FLWFYIYYAV VAGLFAAFWF AYSPHRWQYW SVLGTALIIF NTYFSVQVSV AINAWYGPFY
     DLIQQALART APVTAGQLYS GMIGFSGIAF VAVTVGVLNL FFVSHYIFRW RTAMNEFYVA
     HWPRLRHVEG ASQRVQEDTM RFSSTVERLG VGLVSSIMTL IAFLPVLFKF SEQVNVLPIV
     GEIPHALVWA AVFWSVFGTV FLAAVGIKLP GLEFRNQRVE AAYRKELVYG EDHEDRADPI
     TLAQLFDNVR RNYFRLYFHY MYFNIARIFY LQADNLFGTF VLVPAIVAGK LTLGVMNQVL
     NVFGQVRESF QYLVNSWTTI VELLSIYKRL KAFESVLVDE PLPEIDRQFI DAGGKEELAL