RS25_RAT
ID RS25_RAT Reviewed; 125 AA.
AC P62853; P25111; Q3SYP7;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=40S ribosomal protein S25;
GN Name=Rps25;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Sprague-Dawley; TISSUE=Liver;
RX PubMed=1354961; DOI=10.1016/s0006-291x(05)81603-1;
RA Chan Y.-L., Wool I.G.;
RT "The primary structure of rat ribosomal protein S25.";
RL Biochem. Biophys. Res. Commun. 186:1688-1693(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS25 family.
CC {ECO:0000305}.
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DR EMBL; X62482; CAA44349.1; -; Genomic_DNA.
DR EMBL; BC103658; AAI03659.1; -; mRNA.
DR PIR; A38969; R3RT25.
DR RefSeq; NP_001005528.1; NM_001005528.1.
DR AlphaFoldDB; P62853; -.
DR SMR; P62853; -.
DR BioGRID; 250779; 5.
DR IntAct; P62853; 5.
DR MINT; P62853; -.
DR STRING; 10116.ENSRNOP00000033144; -.
DR iPTMnet; P62853; -.
DR PhosphoSitePlus; P62853; -.
DR jPOST; P62853; -.
DR PaxDb; P62853; -.
DR PRIDE; P62853; -.
DR GeneID; 122799; -.
DR KEGG; rno:122799; -.
DR UCSC; RGD:621043; rat.
DR CTD; 6230; -.
DR RGD; 621043; Rps25.
DR eggNOG; KOG1767; Eukaryota.
DR HOGENOM; CLU_129470_0_1_1; -.
DR InParanoid; P62853; -.
DR OrthoDB; 1552294at2759; -.
DR PhylomeDB; P62853; -.
DR TreeFam; TF314909; -.
DR Reactome; R-RNO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-RNO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-RNO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-RNO-72649; Translation initiation complex formation.
DR Reactome; R-RNO-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-RNO-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR Reactome; R-RNO-72702; Ribosomal scanning and start codon recognition.
DR Reactome; R-RNO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-RNO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-RNO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:P62853; -.
DR Proteomes; UP000002494; Unplaced.
DR Genevisible; P62853; RN.
DR GO; GO:0022626; C:cytosolic ribosome; ISO:RGD.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:RGD.
DR GO; GO:0005730; C:nucleolus; ISO:RGD.
DR GO; GO:0005634; C:nucleus; IDA:RGD.
DR GO; GO:0005844; C:polysome; IDA:RGD.
DR GO; GO:0014069; C:postsynaptic density; ISO:RGD.
DR GO; GO:0005840; C:ribosome; ISO:RGD.
DR GO; GO:0045202; C:synapse; ISO:RGD.
DR GO; GO:0003735; F:structural constituent of ribosome; IMP:RGD.
DR GO; GO:0034198; P:cellular response to amino acid starvation; IEP:RGD.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IMP:RGD.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; ISO:RGD.
DR GO; GO:0006364; P:rRNA processing; ISO:RGD.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR004977; Ribosomal_S25.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR12850; PTHR12850; 1.
DR Pfam; PF03297; Ribosomal_S25; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..125
FT /note="40S ribosomal protein S25"
FT /id="PRO_0000192871"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 43
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P62852"
FT MOD_RES 52
FT /note="N6-acetyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P62851"
FT MOD_RES 52
FT /note="N6-succinyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P62852"
FT MOD_RES 60
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P62851"
FT MOD_RES 66
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P62851"
FT MOD_RES 94
FT /note="N6-acetyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P62851"
FT MOD_RES 94
FT /note="N6-succinyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P62852"
SQ SEQUENCE 125 AA; 13742 MW; B8E05F04FCF2F1A9 CRC64;
MPPKDDKKKK DAGKSAKKDK DPVNKSGGKA KKKKWSKGKV RDKLNNLVLF DKATYDKLCK
EVPNYKLITP AVVSERLKIR GSLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKGGDAPA
AGEDA
