RS27A_CAEEL
ID RS27A_CAEEL Reviewed; 163 AA.
AC P37165; Q07372; Q8MXV5; Q9N5P1;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Ubiquitin-like protein 1-40S ribosomal protein S27a;
DE Contains:
DE RecName: Full=Ubiquitin-like protein 1;
DE Contains:
DE RecName: Full=40S ribosomal protein S27a;
GN Name=ubl-1; ORFNames=H06I04.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A).
RX PubMed=7690036; DOI=10.1016/s0021-9258(19)36550-0;
RA Jones D., Candido E.P.M.;
RT "Novel ubiquitin-like ribosomal protein fusion genes from the nematodes
RT Caenorhabditis elegans and Caenorhabditis briggsae.";
RL J. Biol. Chem. 268:19545-19551(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a;
CC IsoId=P37165-1; Sequence=Displayed;
CC Name=b;
CC IsoId=P37165-2; Sequence=VSP_038215, VSP_038216;
CC -!- SIMILARITY: In the N-terminal section; belongs to the ubiquitin family.
CC {ECO:0000305}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the eukaryotic
CC ribosomal protein eS31 family. {ECO:0000305}.
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DR EMBL; L16530; AAA28161.1; -; mRNA.
DR EMBL; FO081532; CCD72254.1; -; Genomic_DNA.
DR EMBL; FO081532; CCD72255.1; -; Genomic_DNA.
DR PIR; A48766; A48766.
DR RefSeq; NP_001022637.1; NM_001027466.4. [P37165-2]
DR RefSeq; NP_741102.1; NM_171089.5. [P37165-1]
DR AlphaFoldDB; P37165; -.
DR SMR; P37165; -.
DR BioGRID; 40658; 85.
DR DIP; DIP-26542N; -.
DR IntAct; P37165; 2.
DR STRING; 6239.H06I04.4a.2; -.
DR EPD; P37165; -.
DR PaxDb; P37165; -.
DR PeptideAtlas; P37165; -.
DR EnsemblMetazoa; H06I04.4a.1; H06I04.4a.1; WBGene00006725. [P37165-1]
DR EnsemblMetazoa; H06I04.4a.2; H06I04.4a.2; WBGene00006725. [P37165-1]
DR EnsemblMetazoa; H06I04.4b.1; H06I04.4b.1; WBGene00006725. [P37165-2]
DR GeneID; 175413; -.
DR KEGG; cel:CELE_H06I04.4; -.
DR UCSC; H06I04.4a.1; c. elegans. [P37165-1]
DR CTD; 175413; -.
DR WormBase; H06I04.4a; CE20938; WBGene00006725; ubl-1. [P37165-1]
DR WormBase; H06I04.4b; CE31022; WBGene00006725; ubl-1. [P37165-2]
DR eggNOG; KOG0004; Eukaryota.
DR GeneTree; ENSGT00970000196131; -.
DR HOGENOM; CLU_010412_2_0_1; -.
DR InParanoid; P37165; -.
DR OMA; FMAQHAN; -.
DR OrthoDB; 1536766at2759; -.
DR PhylomeDB; P37165; -.
DR PRO; PR:P37165; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00006725; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031386; F:protein tag; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0019941; P:modification-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 6.20.50.150; -; 1.
DR InterPro; IPR002906; Ribosomal_S27a.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR InterPro; IPR038582; S27a-like_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR019954; Ubiquitin_CS.
DR InterPro; IPR019956; Ubiquitin_dom.
DR Pfam; PF01599; Ribosomal_S27; 1.
DR Pfam; PF00240; ubiquitin; 1.
DR PRINTS; PR00348; UBIQUITIN.
DR SMART; SM01402; Ribosomal_S27; 1.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF54236; SSF54236; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
DR PROSITE; PS00299; UBIQUITIN_1; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Isopeptide bond; Metal-binding; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; Zinc; Zinc-finger.
FT CHAIN 1..70
FT /note="Ubiquitin-like protein 1"
FT /id="PRO_0000114887"
FT CHAIN 71..163
FT /note="40S ribosomal protein S27a"
FT /id="PRO_0000137668"
FT DOMAIN 1..70
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00214"
FT ZN_FING 115..138
FT /note="C4-type"
FT CROSSLNK 70
FT /note="Glycyl lysine isopeptide (Gly-Lys) (interchain with
FT K-? in acceptor proteins)"
FT VAR_SEQ 45..47
FT /note="GRQ -> ARG (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_038215"
FT VAR_SEQ 48..163
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_038216"
SQ SEQUENCE 163 AA; 18098 MW; 17A6FEE77DD61624 CRC64;
MVFVKTLHRT LFLEVAANED VLSIKQKIEA AEGIPAEEQR LCYAGRQLED SDCGIDSEAT
IYVNLELLGG AKKRKKKVYT TPKKNKRKPK KVKLAVLKYY KIDENGKITR LRKECQQPSC
GGGVFMAQHA NRHYCGRCHD TLVVDTATAA ATSGEKGGKK GKK
