ID   BACE_BACAM              Reviewed;         393 AA.
AC   Q8KWS7;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Putative bacilysin exporter BacE;
GN   Name=bacE;
OS   Bacillus amyloliquefaciens (Bacillus velezensis).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus amyloliquefaciens group.
OX   NCBI_TaxID=1390;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15841;
RX   PubMed=15609023; DOI=10.1007/s00203-004-0743-8;
RA   Steinborn G., Hajirezaei M.-R., Hofemeister J.;
RT   "bac genes for recombinant bacilysin and anticapsin production in Bacillus
RT   host strains.";
RL   Arch. Microbiol. 183:71-79(2005).
CC   -!- FUNCTION: Part of the bacilysin biosynthesis operon. May be involved in
CC       self-resistance to bacilysin by permitting efflux of this antibiotic
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AF396779; AAM90577.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8KWS7; -.
DR   SMR; Q8KWS7; -.
DR   STRING; 692420.BAMF_3603; -.
DR   eggNOG; COG2814; Bacteria.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR022324; Bacilysin_exporter_BacE_put.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   PRINTS; PR01988; EXPORTERBACE.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..393
FT                   /note="Putative bacilysin exporter BacE"
FT                   /id="PRO_0000084833"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   393 AA;  43191 MW;  0862CB30623F8DAE CRC64;
     MKQLKPNSKY LLFGQALSFM GDYCVLPALL ILSTYYHDYW VTSGVIAVRS IPMVFQPFLG
     VLVDRLDRVK IMLWTDVIRG VIFLGLTFLP KGEYPLLFLA LLFVSYGSGV FFNPARLAVM
     SSLEADIKNI NTLFAKATTI SIIVGAAAGG LFLLGGSVEL AVAFNGVTYL VSAFFISRIK
     LQYVPIQSEN VREAFQSFKE GLKEIKTNAF VLNAMFTMIT MALLWGVVYS YFPIVSRFLG
     DGEIGNFLLT FCIGFGGFIG AALVSKWGFN NNKGLMYFTV LSIVSLALFL FTPIFAVSVI
     AAILFFIAME YGEVLAKVKV QENAANQIQG RIFSVAEASI GLCIAVGSML INIVDAAVIM
     AFIVLLVSGL FLHTKLVNKS FSERNNESEQ IHL