RS28_PIG
ID RS28_PIG Reviewed; 69 AA.
AC Q6QAT1;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 2.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=40S ribosomal protein S28;
GN Name=RPS28;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Lee H.Y., Cui X.S., Jeong Y.J., Shin M.L., Hwang K.C., Kim N.H.;
RT "Identification of differentially expressed genes in porcine embryos.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0007744|PDB:3J7P, ECO:0007744|PDB:3J7R}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.50 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24930395; DOI=10.1016/j.cell.2014.05.024;
RA Voorhees R.M., Fernandez I.S., Scheres S.H., Hegde R.S.;
RT "Structure of the mammalian ribosome-Sec61 complex to 3.4 A resolution.";
RL Cell 157:1632-1643(2014).
CC -!- SUBUNIT: Component of the 40S small ribosomal subunit.
CC {ECO:0000269|PubMed:24930395}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:P62857}. Cytoplasm
CC {ECO:0000269|PubMed:24930395}. Rough endoplasmic reticulum
CC {ECO:0000269|PubMed:24930395}. Note=Detected on cytosolic polysomes (By
CC similarity). Detected in ribosomes that are associated with the rough
CC endoplasmic reticulum (PubMed:24930395). {ECO:0000250|UniProtKB:P62857,
CC ECO:0000269|PubMed:24930395}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS28 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAS55896.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AY550038; AAS55896.1; ALT_INIT; mRNA.
DR RefSeq; NP_001001587.1; NM_001001587.1.
DR RefSeq; XP_013842818.1; XM_013987364.1.
DR PDB; 3J7P; EM; 3.50 A; Sc=1-69.
DR PDB; 3J7R; EM; 3.90 A; Sc=1-69.
DR PDBsum; 3J7P; -.
DR PDBsum; 3J7R; -.
DR AlphaFoldDB; Q6QAT1; -.
DR SMR; Q6QAT1; -.
DR STRING; 9823.ENSSSCP00000014450; -.
DR PaxDb; Q6QAT1; -.
DR PeptideAtlas; Q6QAT1; -.
DR PRIDE; Q6QAT1; -.
DR Ensembl; ENSSSCT00000014851; ENSSSCP00000014450; ENSSSCG00000013597.
DR Ensembl; ENSSSCT00015102681; ENSSSCP00015042678; ENSSSCG00015076105.
DR Ensembl; ENSSSCT00025023327; ENSSSCP00025009750; ENSSSCG00025017262.
DR Ensembl; ENSSSCT00030024856; ENSSSCP00030011102; ENSSSCG00030018006.
DR Ensembl; ENSSSCT00035098887; ENSSSCP00035041815; ENSSSCG00035073015.
DR Ensembl; ENSSSCT00040003494; ENSSSCP00040001065; ENSSSCG00040002825.
DR Ensembl; ENSSSCT00045052072; ENSSSCP00045036239; ENSSSCG00045030525.
DR Ensembl; ENSSSCT00055013312; ENSSSCP00055010465; ENSSSCG00055006878.
DR Ensembl; ENSSSCT00060030186; ENSSSCP00060012962; ENSSSCG00060022239.
DR Ensembl; ENSSSCT00065054864; ENSSSCP00065023839; ENSSSCG00065040129.
DR Ensembl; ENSSSCT00070050597; ENSSSCP00070042768; ENSSSCG00070025313.
DR GeneID; 414420; -.
DR KEGG; ssc:414420; -.
DR CTD; 6234; -.
DR VGNC; VGNC:100854; RPS28.
DR eggNOG; KOG3502; Eukaryota.
DR GeneTree; ENSGT00910000144227; -.
DR HOGENOM; CLU_178987_1_0_1; -.
DR InParanoid; Q6QAT1; -.
DR OMA; MHGEASQ; -.
DR OrthoDB; 1578965at2759; -.
DR TreeFam; TF300136; -.
DR Reactome; R-SSC-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-SSC-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-SSC-72649; Translation initiation complex formation.
DR Reactome; R-SSC-72702; Ribosomal scanning and start codon recognition.
DR Reactome; R-SSC-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-SSC-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-SSC-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR Proteomes; UP000008227; Chromosome 2.
DR Proteomes; UP000314985; Chromosome 2.
DR Bgee; ENSSSCG00000013597; Expressed in subcutaneous adipose tissue and 44 other tissues.
DR Genevisible; Q6QAT1; SS.
DR GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; IDA:UniProtKB.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR GO; GO:0042254; P:ribosome biogenesis; ISS:UniProtKB.
DR CDD; cd04457; S1_S28E; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR HAMAP; MF_00292; Ribosomal_S28e; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR000289; Ribosomal_S28e.
DR InterPro; IPR028626; Ribosomal_S28e_CS.
DR PANTHER; PTHR10769; PTHR10769; 1.
DR Pfam; PF01200; Ribosomal_S28e; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR PROSITE; PS00961; RIBOSOMAL_S28E; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Cytoplasm; Endoplasmic reticulum;
KW Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..69
FT /note="40S ribosomal protein S28"
FT /id="PRO_0000136824"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:P62859"
FT MOD_RES 41
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P62857"
SQ SEQUENCE 69 AA; 7841 MW; 49902FE9376EB74F CRC64;
MDTSRVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV REGDVLTLLE
SEREARRLR
