RS28_RAT
ID RS28_RAT Reviewed; 69 AA.
AC P62859; P25112;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=40S ribosomal protein S28;
GN Name=Rps28;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], ACETYLATION AT MET-1, AND PROTEIN SEQUENCE OF
RP 36-68.
RC STRAIN=Sprague-Dawley; TISSUE=Liver;
RX PubMed=1679328; DOI=10.1016/0006-291x(91)91371-i;
RA Chan Y.-L., Olvera J., Wool I.G.;
RT "The primary structure of rat ribosomal protein S28.";
RL Biochem. Biophys. Res. Commun. 179:314-318(1991).
CC -!- SUBUNIT: Component of the 40S small ribosomal subunit.
CC {ECO:0000250|UniProtKB:Q6QAT1}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:P62857}. Cytoplasm
CC {ECO:0000250|UniProtKB:P62857}. Rough endoplasmic reticulum
CC {ECO:0000250|UniProtKB:Q6QAT1}. Note=Detected on cytosolic polysomes
CC (By similarity). Detected in ribosomes that are associated with the
CC rough endoplasmic reticulum (By similarity).
CC {ECO:0000250|UniProtKB:P62857, ECO:0000250|UniProtKB:Q6QAT1}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS28 family.
CC {ECO:0000305}.
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DR EMBL; X59277; CAA41967.1; -; mRNA.
DR PIR; JQ1170; R3RT28.
DR RefSeq; NP_001099200.1; NM_001105730.1.
DR AlphaFoldDB; P62859; -.
DR SMR; P62859; -.
DR IntAct; P62859; 4.
DR STRING; 10116.ENSRNOP00000025380; -.
DR iPTMnet; P62859; -.
DR PhosphoSitePlus; P62859; -.
DR jPOST; P62859; -.
DR PaxDb; P62859; -.
DR PRIDE; P62859; -.
DR Ensembl; ENSRNOT00000025380; ENSRNOP00000088092; ENSRNOG00000049442.
DR Ensembl; ENSRNOT00000068323; ENSRNOP00000060568; ENSRNOG00000042886.
DR Ensembl; ENSRNOT00000114114; ENSRNOP00000078298; ENSRNOG00000049442.
DR GeneID; 691531; -.
DR KEGG; rno:691531; -.
DR UCSC; RGD:621046; rat.
DR CTD; 6234; -.
DR RGD; 621046; Rps28.
DR eggNOG; KOG3502; Eukaryota.
DR GeneTree; ENSGT00910000144227; -.
DR HOGENOM; CLU_178987_1_0_1; -.
DR InParanoid; P62859; -.
DR OMA; MHGEASQ; -.
DR OrthoDB; 1578965at2759; -.
DR PhylomeDB; P62859; -.
DR TreeFam; TF300136; -.
DR Reactome; R-RNO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-RNO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-RNO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-RNO-72649; Translation initiation complex formation.
DR Reactome; R-RNO-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-RNO-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR Reactome; R-RNO-72702; Ribosomal scanning and start codon recognition.
DR Reactome; R-RNO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-RNO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-RNO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:P62859; -.
DR Proteomes; UP000002494; Chromosome 16.
DR Proteomes; UP000002494; Chromosome 7.
DR Bgee; ENSRNOG00000042886; Expressed in pancreas and 18 other tissues.
DR Genevisible; P62859; RN.
DR GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; ISS:UniProtKB.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:RGD.
DR GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR GO; GO:0003735; F:structural constituent of ribosome; ISO:RGD.
DR GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; ISO:RGD.
DR GO; GO:0042254; P:ribosome biogenesis; ISS:UniProtKB.
DR GO; GO:0006364; P:rRNA processing; ISO:RGD.
DR GO; GO:0006412; P:translation; TAS:ProtInc.
DR CDD; cd04457; S1_S28E; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR HAMAP; MF_00292; Ribosomal_S28e; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR000289; Ribosomal_S28e.
DR InterPro; IPR028626; Ribosomal_S28e_CS.
DR PANTHER; PTHR10769; PTHR10769; 1.
DR Pfam; PF01200; Ribosomal_S28e; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR PROSITE; PS00961; RIBOSOMAL_S28E; 1.
PE 1: Evidence at protein level;
KW Acetylation; Cytoplasm; Direct protein sequencing; Endoplasmic reticulum;
KW Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..69
FT /note="40S ribosomal protein S28"
FT /id="PRO_0000136825"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000305|PubMed:1679328"
FT MOD_RES 41
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P62857"
SQ SEQUENCE 69 AA; 7841 MW; 49902FE9376EB74F CRC64;
MDTSRVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV REGDVLTLLE
SEREARRLR