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RS28_RAT
ID   RS28_RAT                Reviewed;          69 AA.
AC   P62859; P25112;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=40S ribosomal protein S28;
GN   Name=Rps28;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], ACETYLATION AT MET-1, AND PROTEIN SEQUENCE OF
RP   36-68.
RC   STRAIN=Sprague-Dawley; TISSUE=Liver;
RX   PubMed=1679328; DOI=10.1016/0006-291x(91)91371-i;
RA   Chan Y.-L., Olvera J., Wool I.G.;
RT   "The primary structure of rat ribosomal protein S28.";
RL   Biochem. Biophys. Res. Commun. 179:314-318(1991).
CC   -!- SUBUNIT: Component of the 40S small ribosomal subunit.
CC       {ECO:0000250|UniProtKB:Q6QAT1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P62857}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P62857}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q6QAT1}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:P62857, ECO:0000250|UniProtKB:Q6QAT1}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS28 family.
CC       {ECO:0000305}.
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DR   EMBL; X59277; CAA41967.1; -; mRNA.
DR   PIR; JQ1170; R3RT28.
DR   RefSeq; NP_001099200.1; NM_001105730.1.
DR   AlphaFoldDB; P62859; -.
DR   SMR; P62859; -.
DR   IntAct; P62859; 4.
DR   STRING; 10116.ENSRNOP00000025380; -.
DR   iPTMnet; P62859; -.
DR   PhosphoSitePlus; P62859; -.
DR   jPOST; P62859; -.
DR   PaxDb; P62859; -.
DR   PRIDE; P62859; -.
DR   Ensembl; ENSRNOT00000025380; ENSRNOP00000088092; ENSRNOG00000049442.
DR   Ensembl; ENSRNOT00000068323; ENSRNOP00000060568; ENSRNOG00000042886.
DR   Ensembl; ENSRNOT00000114114; ENSRNOP00000078298; ENSRNOG00000049442.
DR   GeneID; 691531; -.
DR   KEGG; rno:691531; -.
DR   UCSC; RGD:621046; rat.
DR   CTD; 6234; -.
DR   RGD; 621046; Rps28.
DR   eggNOG; KOG3502; Eukaryota.
DR   GeneTree; ENSGT00910000144227; -.
DR   HOGENOM; CLU_178987_1_0_1; -.
DR   InParanoid; P62859; -.
DR   OMA; MHGEASQ; -.
DR   OrthoDB; 1578965at2759; -.
DR   PhylomeDB; P62859; -.
DR   TreeFam; TF300136; -.
DR   Reactome; R-RNO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-RNO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-RNO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-RNO-72649; Translation initiation complex formation.
DR   Reactome; R-RNO-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-RNO-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-RNO-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-RNO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-RNO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-RNO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P62859; -.
DR   Proteomes; UP000002494; Chromosome 16.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Bgee; ENSRNOG00000042886; Expressed in pancreas and 18 other tissues.
DR   Genevisible; P62859; RN.
DR   GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; ISS:UniProtKB.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:RGD.
DR   GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:RGD.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; ISO:RGD.
DR   GO; GO:0042254; P:ribosome biogenesis; ISS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; ISO:RGD.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   CDD; cd04457; S1_S28E; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00292; Ribosomal_S28e; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR000289; Ribosomal_S28e.
DR   InterPro; IPR028626; Ribosomal_S28e_CS.
DR   PANTHER; PTHR10769; PTHR10769; 1.
DR   Pfam; PF01200; Ribosomal_S28e; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS00961; RIBOSOMAL_S28E; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Cytoplasm; Direct protein sequencing; Endoplasmic reticulum;
KW   Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..69
FT                   /note="40S ribosomal protein S28"
FT                   /id="PRO_0000136825"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000305|PubMed:1679328"
FT   MOD_RES         41
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P62857"
SQ   SEQUENCE   69 AA;  7841 MW;  49902FE9376EB74F CRC64;
     MDTSRVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV REGDVLTLLE
     SEREARRLR
 
 
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