ID   RS2_BACSU               Reviewed;         246 AA.
AC   P21464; O31747;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=30S ribosomal protein S2;
DE   AltName: Full=BS1;
DE   AltName: Full=Vegetative protein 209;
DE            Short=VEG209;
GN   Name=rpsB; OrderedLocusNames=BSU16490;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-20.
RX   PubMed=6806564; DOI=10.1007/bf00330792;
RA   Higo K., Otaka E., Osawa S.;
RT   "Purification and characterization of 30S ribosomal proteins from Bacillus
RT   subtilis: correlation to Escherichia coli 30S proteins.";
RL   Mol. Gen. Genet. 185:239-244(1982).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-20.
RC   STRAIN=168 / IS58;
RX   PubMed=9298659; DOI=10.1002/elps.1150180820;
RA   Antelmann H., Bernhardt J., Schmid R., Mach H., Voelker U., Hecker M.;
RT   "First steps from a two-dimensional protein index towards a response-
RT   regulation map for Bacillus subtilis.";
RL   Electrophoresis 18:1451-1463(1997).
RN   [4]
RP   INTERACTION WITH BRXC, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=168 / CU1065 {ECO:0000303|PubMed:33722570};
RX   PubMed=33722570; DOI=10.1016/j.redox.2021.101935;
RA   Gaballa A., Su T.T., Helmann J.D.;
RT   "The Bacillus subtilis monothiol bacilliredoxin BrxC (YtxJ) and the Bdr
RT   (YpdA) disulfide reductase reduce S-bacillithiolated proteins.";
RL   Redox Biol. 42:101935-101935(2021).
RN   [5] {ECO:0007744|PDB:6HA1, ECO:0007744|PDB:6HA8}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.10 ANGSTROMS) OF 1-246 WITH AND WITHOUT
RP   VIRGINIAMYCIN M, AND SUBUNIT.
RX   PubMed=30126986; DOI=10.1073/pnas.1808535115;
RA   Crowe-McAuliffe C., Graf M., Huter P., Takada H., Abdelshahid M.,
RA   Novacek J., Murina V., Atkinson G.C., Hauryliuk V., Wilson D.N.;
RT   "Structural basis for antibiotic resistance mediated by the Bacillus
RT   subtilis ABCF ATPase VmlR.";
RL   Proc. Natl. Acad. Sci. U.S.A. 115:8978-8983(2018).
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit (PubMed:30126986). Interacts
CC       with BrxC (PubMed:33722570). {ECO:0000269|PubMed:30126986,
CC       ECO:0000269|PubMed:33722570}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC       {ECO:0000305}.
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DR   EMBL; AL009126; CAB13522.1; -; Genomic_DNA.
DR   PIR; A69699; A69699.
DR   RefSeq; NP_389531.1; NC_000964.3.
DR   RefSeq; WP_003220918.1; NZ_JNCM01000035.1.
DR   PDB; 3J9W; EM; 3.90 A; AB=1-246.
DR   PDB; 5NJT; EM; 3.80 A; B=6-229.
DR   PDB; 6HA1; EM; 3.10 A; b=1-246.
DR   PDB; 6HA8; EM; 3.50 A; b=1-246.
DR   PDB; 6HTQ; EM; 4.50 A; b=9-226.
DR   PDB; 7O5B; EM; 3.33 A; B=1-246.
DR   PDB; 7QV2; EM; 3.50 A; b=1-246.
DR   PDBsum; 3J9W; -.
DR   PDBsum; 5NJT; -.
DR   PDBsum; 6HA1; -.
DR   PDBsum; 6HA8; -.
DR   PDBsum; 6HTQ; -.
DR   PDBsum; 7O5B; -.
DR   PDBsum; 7QV2; -.
DR   AlphaFoldDB; P21464; -.
DR   SMR; P21464; -.
DR   DIP; DIP-58541N; -.
DR   IntAct; P21464; 1.
DR   STRING; 224308.BSU16490; -.
DR   jPOST; P21464; -.
DR   PaxDb; P21464; -.
DR   PRIDE; P21464; -.
DR   EnsemblBacteria; CAB13522; CAB13522; BSU_16490.
DR   GeneID; 64303542; -.
DR   GeneID; 939599; -.
DR   KEGG; bsu:BSU16490; -.
DR   PATRIC; fig|224308.179.peg.1790; -.
DR   eggNOG; COG0052; Bacteria.
DR   InParanoid; P21464; -.
DR   OMA; SYIDRAY; -.
DR   PhylomeDB; P21464; -.
DR   BioCyc; BSUB:BSU16490-MON; -.
DR   PRO; PR:P21464; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd01425; RPS2; 1.
DR   HAMAP; MF_00291_B; Ribosomal_S2_B; 1.
DR   InterPro; IPR001865; Ribosomal_S2.
DR   InterPro; IPR005706; Ribosomal_S2_bac/mit/plastid.
DR   InterPro; IPR018130; Ribosomal_S2_CS.
DR   InterPro; IPR023591; Ribosomal_S2_flav_dom_sf.
DR   PANTHER; PTHR12534; PTHR12534; 1.
DR   Pfam; PF00318; Ribosomal_S2; 1.
DR   PRINTS; PR00395; RIBOSOMALS2.
DR   SUPFAM; SSF52313; SSF52313; 1.
DR   TIGRFAMs; TIGR01011; rpsB_bact; 1.
DR   PROSITE; PS00962; RIBOSOMAL_S2_1; 1.
DR   PROSITE; PS00963; RIBOSOMAL_S2_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Direct protein sequencing; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:6806564,
FT                   ECO:0000269|PubMed:9298659"
FT   CHAIN           2..246
FT                   /note="30S ribosomal protein S2"
FT                   /id="PRO_0000134131"
FT   REGION          226..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        7
FT                   /note="K -> H (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   246 AA;  27967 MW;  624D11EE6A12CAD5 CRC64;
     MSVISMKQLL EAGVHFGHQT RRWNPKMKRY IFTERNGIYI IDLQKTVKKV EEAYNFTKNL
     AAEGGKILFV GTKKQAQDSV KEEAQRSGMY YVNQRWLGGT LTNFETIQKR IKRLKDIEKM
     QENGTFDVLP KKEVVQLKKE LERLEKFLGG IKDMKDLPDA LFIIDPRKER IAVAEARKLN
     IPIIGIVDTN CDPDEIDVVI PANDDAIRAV KLLTSKMADA ILEAKQGEEE AEVAEETAPE
     TETTTA