BACR1_HALWC
ID BACR1_HALWC Reviewed; 254 AA.
AC G0LFX8;
DT 14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 1.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=Bacteriorhodopsin-I;
DE Flags: Precursor;
GN Name=bop1; OrderedLocusNames=Hqrw_1016;
OS Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloquadratum.
OX NCBI_TaxID=768065;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=DSM 16854 / JCM 12705 / C23;
RX PubMed=21701686; DOI=10.1371/journal.pone.0020968;
RA Dyall-Smith M., Pfeiffer F., Klee K., Palm P., Gross K., Schuster S.C.,
RA Rampp M., Oesterhelt D.;
RT "Haloquadratum walsbyi: limited diversity in a global pond.";
RL PLoS ONE 6:E20968-E20968(2011).
CC -!- FUNCTION: Light-driven proton pump. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- PTM: The covalent binding of retinal to the apoprotein, bacterioopsin,
CC generates bacteriorhodopsin. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the archaeal/bacterial/fungal opsin family.
CC {ECO:0000305}.
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DR EMBL; FR746099; CCC38998.1; -; Genomic_DNA.
DR RefSeq; WP_011570311.1; NC_017459.1.
DR PDB; 4WAV; X-ray; 2.80 A; A/B=1-254.
DR PDBsum; 4WAV; -.
DR AlphaFoldDB; G0LFX8; -.
DR SMR; G0LFX8; -.
DR TCDB; 3.E.1.1.3; the ion-translocating microbial rhodopsin (mr) family.
DR EnsemblBacteria; CCC38998; CCC38998; Hqrw_1016.
DR GeneID; 4193772; -.
DR KEGG; hwc:Hqrw_1016; -.
DR HOGENOM; CLU_054785_5_1_2; -.
DR OMA; VGWAIYP; -.
DR OrthoDB; 90087at2157; -.
DR Proteomes; UP000007954; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR InterPro; IPR001425; Arc/bac/fun_rhodopsins.
DR InterPro; IPR018229; Rhodopsin_retinal_BS.
DR PANTHER; PTHR28286; PTHR28286; 1.
DR Pfam; PF01036; Bac_rhodopsin; 1.
DR PRINTS; PR00251; BACTRLOPSIN.
DR SMART; SM01021; Bac_rhodopsin; 1.
DR PROSITE; PS00950; BACTERIAL_OPSIN_1; 1.
DR PROSITE; PS00327; BACTERIAL_OPSIN_RET; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell membrane; Chromophore; Hydrogen ion transport;
KW Ion transport; Membrane; Photoreceptor protein;
KW Pyrrolidone carboxylic acid; Receptor; Retinal protein;
KW Sensory transduction; Transmembrane; Transmembrane helix; Transport.
FT PROPEP 1..6
FT /evidence="ECO:0000250"
FT /id="PRO_0000428844"
FT CHAIN 7..254
FT /note="Bacteriorhodopsin-I"
FT /id="PRO_0000428845"
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT SITE 93
FT /note="Primary proton acceptor"
FT /evidence="ECO:0000250"
FT MOD_RES 7
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000250"
FT MOD_RES 224
FT /note="N6-(retinylidene)lysine"
FT /evidence="ECO:0000250"
FT HELIX 17..37
FT /evidence="ECO:0007829|PDB:4WAV"
FT HELIX 44..68
FT /evidence="ECO:0007829|PDB:4WAV"
FT TURN 69..72
FT /evidence="ECO:0007829|PDB:4WAV"
FT STRAND 75..77
FT /evidence="ECO:0007829|PDB:4WAV"
FT STRAND 83..85
FT /evidence="ECO:0007829|PDB:4WAV"
FT HELIX 89..109
FT /evidence="ECO:0007829|PDB:4WAV"
FT HELIX 113..135
FT /evidence="ECO:0007829|PDB:4WAV"
FT HELIX 139..168
FT /evidence="ECO:0007829|PDB:4WAV"
FT HELIX 173..190
FT /evidence="ECO:0007829|PDB:4WAV"
FT HELIX 193..199
FT /evidence="ECO:0007829|PDB:4WAV"
FT TURN 201..204
FT /evidence="ECO:0007829|PDB:4WAV"
FT HELIX 209..232
FT /evidence="ECO:0007829|PDB:4WAV"
SQ SEQUENCE 254 AA; 27423 MW; 110CC901DDF50298 CRC64;
MSQLALQMSS LGVEGEGIWL ALGTIGMLLG MLYFIADGLD VQDPRQKEFY VITILIPAIA
AASYLSMFFG FGLTEVSLAN GRVVDVYWAR YADWLFTTPL LLLDIGLLAG ASQRDIGALV
GIDAFMIVTG LVATLTKVVV ARYAFWTIST ISMVFLLYYL VAVFGEAVSD ADEDTRSTFN
ALRNIILVTW AIYPVAWLVG TEGLALTGLY GETLLFMVLD LVAKVGFGFI LLRSRAIMGG
GSEPTPSAQE TAAD
