ID   BACR_HALHM              Reviewed;         204 AA.
AC   P33969;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Bacteriorhodopsin;
DE            Short=BR;
DE   Flags: Fragment;
GN   Name=bop;
OS   Halobacterium halobium (strain mex).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=33003;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1479357; DOI=10.1099/00221287-138-11-2389;
RA   Otomo J., Urabe Y., Tomioka H., Sasabe H.;
RT   "The primary structures of helices A to G of three new bacteriorhodopsin-
RT   like retinal proteins.";
RL   J. Gen. Microbiol. 138:2389-2396(1992).
CC   -!- FUNCTION: Light-driven proton pump.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the archaeal/bacterial/fungal opsin family.
CC       {ECO:0000305}.
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DR   EMBL; D11056; BAA01799.1; -; Genomic_DNA.
DR   PIR; C47686; C47686.
DR   AlphaFoldDB; P33969; -.
DR   SMR; P33969; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR   InterPro; IPR001425; Arc/bac/fun_rhodopsins.
DR   InterPro; IPR018229; Rhodopsin_retinal_BS.
DR   PANTHER; PTHR28286; PTHR28286; 1.
DR   Pfam; PF01036; Bac_rhodopsin; 1.
DR   PRINTS; PR00251; BACTRLOPSIN.
DR   SMART; SM01021; Bac_rhodopsin; 1.
DR   PROSITE; PS00950; BACTERIAL_OPSIN_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Chromophore; Hydrogen ion transport; Ion transport;
KW   Membrane; Photoreceptor protein; Receptor; Retinal protein;
KW   Sensory transduction; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           <1..>204
FT                   /note="Bacteriorhodopsin"
FT                   /id="PRO_0000196269"
FT   TRANSMEM        <1..16
FT                   /note="Helical; Name=Helix A"
FT   TOPO_DOM        17..30
FT                   /note="Cytoplasmic"
FT   TRANSMEM        31..50
FT                   /note="Helical; Name=Helix B"
FT   TOPO_DOM        51..70
FT                   /note="Extracellular"
FT   TRANSMEM        71..90
FT                   /note="Helical; Name=Helix C"
FT   TOPO_DOM        91..96
FT                   /note="Cytoplasmic"
FT   TRANSMEM        97..116
FT                   /note="Helical; Name=Helix D"
FT   TOPO_DOM        117..123
FT                   /note="Extracellular"
FT   TRANSMEM        124..143
FT                   /note="Helical; Name=Helix E"
FT   TOPO_DOM        144..166
FT                   /note="Cytoplasmic"
FT   TRANSMEM        167..186
FT                   /note="Helical; Name=Helix F"
FT   TOPO_DOM        187..192
FT                   /note="Extracellular"
FT   TRANSMEM        193..>204
FT                   /note="Helical; Name=Helix G"
FT   NON_TER         1
FT   NON_TER         204
SQ   SEQUENCE   204 AA;  22137 MW;  A0C3D8214C888B2F CRC64;
     GIGTLLMLIG TFYFIARGWG VTDKKAREYY AITILVPGIA SAAYLSMFFG IGLTTVEVAG
     MAEPLEIYYA RYADWLFTTP LLLLDLALLA NADRTTIGTL IGVDALMIVT GLIGALSHTP
     LARYTWWLFS TIAFLFVLYY LLTVLRSAAA ELSEDVQTTF NTLTALVAVL WTAYPILWII
     GTEGAGVVGL GVETLAFMVL DVTA