ID   BACS_HALSD              Reviewed;         254 AA.
AC   O93743;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Sensory rhodopsin;
DE            Short=SR;
GN   Name=sop;
OS   Halorubrum sodomense.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum.
OX   NCBI_TaxID=35743;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9878396; DOI=10.1006/jmbi.1998.2286;
RA   Ihara K., Umemura T., Katagiri I., Kitajima-Ihara T., Sugiyama Y.,
RA   Kimura Y., Mukohata Y.;
RT   "Evolution of the archaeal rhodopsins: evolution rate changes by gene
RT   duplication and functional differentiation.";
RL   J. Mol. Biol. 285:163-174(1999).
CC   -!- FUNCTION: Involved in the control of phototaxis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the archaeal/bacterial/fungal opsin family.
CC       {ECO:0000305}.
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DR   EMBL; AB009623; BAA75203.1; -; Genomic_DNA.
DR   PIR; T43843; T43843.
DR   AlphaFoldDB; O93743; -.
DR   SMR; O93743; -.
DR   STRING; 35743.SAMN04487937_1712; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR   InterPro; IPR001425; Arc/bac/fun_rhodopsins.
DR   InterPro; IPR018229; Rhodopsin_retinal_BS.
DR   PANTHER; PTHR28286; PTHR28286; 1.
DR   Pfam; PF01036; Bac_rhodopsin; 1.
DR   PRINTS; PR00251; BACTRLOPSIN.
DR   SMART; SM01021; Bac_rhodopsin; 1.
DR   PROSITE; PS00950; BACTERIAL_OPSIN_1; 1.
DR   PROSITE; PS00327; BACTERIAL_OPSIN_RET; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Chromophore; Membrane; Photoreceptor protein; Receptor;
KW   Retinal protein; Sensory transduction; Transmembrane; Transmembrane helix.
FT   CHAIN           1..254
FT                   /note="Sensory rhodopsin"
FT                   /id="PRO_0000196278"
FT   TOPO_DOM        1..4
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        5..26
FT                   /note="Helical; Name=Helix A"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        27..35
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        36..57
FT                   /note="Helical; Name=Helix B"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        58..71
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        72..93
FT                   /note="Helical; Name=Helix C"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        94..96
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        97..119
FT                   /note="Helical; Name=Helix D"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        120..123
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        124..151
FT                   /note="Helical; Name=Helix E"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        152..154
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        155..182
FT                   /note="Helical; Name=Helix F"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        183..190
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        191..223
FT                   /note="Helical; Name=Helix G"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        224..254
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   REGION          231..254
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         206
FT                   /note="N6-(retinylidene)lysine"
SQ   SEQUENCE   254 AA;  26282 MW;  92F5428824AD56D7 CRC64;
     MTGAVTSAYW LAAVAFLIGV GITAALYAKL EGSRARTRLA ALAVIPGFAG LSYVGMALGI
     GTVTVNGAEL VGLRYVDWVV TTPLLVGFIG YNAGASRRAI AGVMIADALM IVFGAAAVVS
     GGTLKWALFG VSALFHVSLF AYLYVIFPGG IPDDPMQRGL FSLLKNHVGL LWLAYPFVWL
     MGPAGIGFTG AVGAALTYAF LDVLAKVPYV YFFYARRQAF IDVTDSRAAA KGDGPAVGGE
     APVATGDDAP TAAD