ID   BACT_LACSP              Reviewed;          41 AA.
AC   P86291;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=Bacteriocin {ECO:0000303|Ref.1};
OS   Lactococcus sp.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus; unclassified Lactococcus.
OX   NCBI_TaxID=44273;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, AND MASS SPECTROMETRY.
RC   STRAIN=M rad 1 {ECO:0000269|Ref.1};
RA   Ingale A.G.;
RT   "Molecular characterisation of bacteriocin from microflora associated with
RT   radish and ginger.";
RL   Submitted (APR-2009) to UniProtKB.
CC   -!- FUNCTION: Bacteriocin active against S.aureus, S.typhi,
CC       B.thuringiensis, Klebsiella sp., E.coli KL16 and E.coli Gj137.
CC       {ECO:0000269|Ref.1}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- MASS SPECTROMETRY: Mass=4223; Mass_error=10; Method=MALDI;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the bacteriocin class IIA/YGNGV family.
CC       {ECO:0000255}.
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DR   AlphaFoldDB; P86291; -.
DR   SMR; P86291; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.130; -; 1.
DR   InterPro; IPR002633; Bacteriocin_IIa.
DR   InterPro; IPR023384; Bacteriocin_IIa_CS.
DR   InterPro; IPR023388; Bacteriocin_IIa_dom_sf.
DR   Pfam; PF01721; Bacteriocin_II; 1.
DR   PROSITE; PS60030; BACTERIOCIN_IIA; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Bacteriocin; Direct protein sequencing;
KW   Disulfide bond; Secreted.
FT   PEPTIDE         1..41
FT                   /note="Bacteriocin"
FT                   /evidence="ECO:0000269|Ref.1"
FT                   /id="PRO_0000377704"
FT   DISULFID        9..14
FT                   /evidence="ECO:0000250|UniProtKB:P83002"
SQ   SEQUENCE   41 AA;  4602 MW;  C6ECC9E69AC16CEA CRC64;
     TSYGNGVHCN KSKCWIDVSE LETYKAGTVS NPKDILWSLK E