ID   BAFL_MOUSE              Reviewed;          90 AA.
AC   Q8BVR0;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Barrier-to-autointegration factor-like protein;
DE            Short=BAF-L;
DE   AltName: Full=Barrier-to-autointegration factor 2;
GN   Name=Banf2; Synonyms=Bafl;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- FUNCTION: May play a role in BANF1 regulation and influence tissue-
CC       specific roles of BANF1. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. Heterodimerizes with BANF1 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}.
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DR   EMBL; AK076863; BAC36510.1; -; mRNA.
DR   EMBL; BC049628; AAH49628.1; -; mRNA.
DR   CCDS; CCDS16813.1; -.
DR   RefSeq; NP_001038215.1; NM_001044750.1.
DR   RefSeq; NP_997158.1; NM_207275.1.
DR   AlphaFoldDB; Q8BVR0; -.
DR   SMR; Q8BVR0; -.
DR   STRING; 10090.ENSMUSP00000046219; -.
DR   PhosphoSitePlus; Q8BVR0; -.
DR   PaxDb; Q8BVR0; -.
DR   PRIDE; Q8BVR0; -.
DR   ProteomicsDB; 265198; -.
DR   Antibodypedia; 48602; 20 antibodies from 10 providers.
DR   DNASU; 403171; -.
DR   Ensembl; ENSMUST00000037722; ENSMUSP00000046219; ENSMUSG00000037307.
DR   Ensembl; ENSMUST00000110032; ENSMUSP00000105659; ENSMUSG00000037307.
DR   GeneID; 403171; -.
DR   KEGG; mmu:403171; -.
DR   UCSC; uc008mqn.1; mouse.
DR   CTD; 140836; -.
DR   MGI; MGI:2684961; Banf2.
DR   VEuPathDB; HostDB:ENSMUSG00000037307; -.
DR   eggNOG; KOG4233; Eukaryota.
DR   GeneTree; ENSGT00940000162003; -.
DR   HOGENOM; CLU_167806_0_0_1; -.
DR   InParanoid; Q8BVR0; -.
DR   OMA; CWVDGVS; -.
DR   OrthoDB; 1617480at2759; -.
DR   PhylomeDB; Q8BVR0; -.
DR   TreeFam; TF315060; -.
DR   BioGRID-ORCS; 403171; 2 hits in 59 CRISPR screens.
DR   ChiTaRS; Banf2; mouse.
DR   PRO; PR:Q8BVR0; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q8BVR0; protein.
DR   Bgee; ENSMUSG00000037307; Expressed in seminiferous tubule of testis and 11 other tissues.
DR   Genevisible; Q8BVR0; MM.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0042802; F:identical protein binding; ISO:MGI.
DR   GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR   GO; GO:0007059; P:chromosome segregation; IBA:GO_Central.
DR   Gene3D; 1.10.150.40; -; 1.
DR   InterPro; IPR004122; BAF_prot.
DR   InterPro; IPR036617; BAF_sf.
DR   PANTHER; PTHR12912; PTHR12912; 1.
DR   Pfam; PF02961; BAF; 1.
DR   SMART; SM01023; BAF; 1.
DR   SUPFAM; SSF47798; SSF47798; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..90
FT                   /note="Barrier-to-autointegration factor-like protein"
FT                   /id="PRO_0000223617"
SQ   SEQUENCE   90 AA;  10267 MW;  E45FE09EF1DA6852 CRC64;
     MDDMSPRLRA FLSEPIGEKD VAWVDGISRE LAINLVTKGF NKAYVLLGQF LLMHKNEAEF
     QRWIICCCGA TECEARQSST CLKEWCSCFL