RS3A_ANOGA
ID RS3A_ANOGA Reviewed; 269 AA.
AC P52813; Q7QAU6;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122};
DE AltName: Full=C3 protein;
GN Name=RpS3A {ECO:0000255|HAMAP-Rule:MF_03122}; Synonyms=C3;
GN ORFNames=AGAP003532;
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Suakoko; TISSUE=Ovary;
RX PubMed=9393444; DOI=10.1007/s004380050590;
RA Reynaud E., Bolshakov V.N., Barajas V.N., Kafatos F.C., Zurita M.;
RT "Antisense suppression of the putative ribosomal protein S3A gene disrupts
RT ovarian development in Drosophila melanogaster.";
RL Mol. Gen. Genet. 256:462-467(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST;
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
CC -!- FUNCTION: Has an essential role in oogenesis. {ECO:0000250}.
CC -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC contains about 33 different proteins and 1 molecule of RNA (18S). The
CC 60S subunit contains about 49 different proteins and 3 molecules of RNA
CC (28S, 5.8S and 5S). {ECO:0000255|HAMAP-Rule:MF_03122}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03122}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS1 family.
CC {ECO:0000255|HAMAP-Rule:MF_03122}.
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DR EMBL; X98186; CAA66861.1; -; mRNA.
DR EMBL; AAAB01008888; EAA08803.3; -; Genomic_DNA.
DR RefSeq; XP_313275.3; XM_313275.4.
DR AlphaFoldDB; P52813; -.
DR SMR; P52813; -.
DR STRING; 7165.AGAP003532-PA; -.
DR PaxDb; P52813; -.
DR GeneID; 1274189; -.
DR KEGG; aga:AgaP_AGAP003532; -.
DR CTD; 1274189; -.
DR VEuPathDB; VectorBase:AGAP003532; -.
DR eggNOG; KOG1628; Eukaryota.
DR HOGENOM; CLU_062507_0_1_1; -.
DR InParanoid; P52813; -.
DR OMA; GQNAYTK; -.
DR OrthoDB; 1207239at2759; -.
DR PhylomeDB; P52813; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_03122; Ribosomal_S3Ae_euk; 1.
DR InterPro; IPR027500; Ribosomal_S1/3_euk.
DR InterPro; IPR001593; Ribosomal_S3Ae.
DR InterPro; IPR018281; Ribosomal_S3Ae_CS.
DR Pfam; PF01015; Ribosomal_S3Ae; 1.
DR SMART; SM01397; Ribosomal_S3Ae; 1.
DR PROSITE; PS01191; RIBOSOMAL_S3AE; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03122"
FT CHAIN 2..269
FT /note="40S ribosomal protein S3a"
FT /id="PRO_0000153528"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 44
FT /note="V -> S (in Ref. 1; CAA66861)"
FT /evidence="ECO:0000305"
FT CONFLICT 118
FT /note="K -> N (in Ref. 1; CAA66861)"
FT /evidence="ECO:0000305"
FT CONFLICT 256
FT /note="D -> V (in Ref. 1; CAA66861)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 269 AA; 29812 MW; D49D6427E377EE80 CRC64;
MAVGKNKGVS KGGKKGSKKK VVDPFTRKDW YDVKAPNMFK NRQVGKTLVN RTQGTKIASD
GLKGRVFEVS LADLQNEPDA ERSFRKFKLV AESVNGRDVL TNFHGMALTT DKLRSMVKKW
QTLIECSVDV KTTDGFMLRV FCIGFTIKDS MSQRKTCYAQ HSQIKNIRAK MTAIIKREIT
STDLKGVVEK LLPDSIAKDI EKACQVVYPL HDVYIRKVKV LKKPRFDLSS LMELHGDGGG
KAAEVSTGAA SGVVVDRPEG YEPPVQASV
