RS3A_LEIMA
ID RS3A_LEIMA Reviewed; 264 AA.
AC Q4FX73; E9AEL7; Q9U4U0;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122};
DE AltName: Full=LmS3a-related protein;
DE Short=LmS3arp;
GN ORFNames=LmjF.35.0400;
GN and
GN ORFNames=LmjF.35.0410;
GN and
GN ORFNames=LmjF.35.0420;
OS Leishmania major.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5664;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND SUBCELLULAR LOCATION.
RC STRAIN=LEM 265;
RX PubMed=10564812; DOI=10.1016/s0378-1119(99)00433-3;
RA Zemzoumi K., Guilvard E., Sereno D., Preto A., Benlemlih M.,
RA Cordeiro Da Silva A., Lemesre J.-L., Ouaissi A.;
RT "Cloning of a Leishmania major gene encoding for an antigen with extensive
RT homology to ribosomal protein S3a.";
RL Gene 240:57-65(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin;
RX PubMed=16020728; DOI=10.1126/science.1112680;
RA Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M.,
RA De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S.,
RA Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K.,
RA Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA Barrell B.G., Myler P.J.;
RT "The genome of the kinetoplastid parasite, Leishmania major.";
RL Science 309:436-442(2005).
CC -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC contains about 33 different proteins and 1 molecule of RNA (18S). The
CC 60S subunit contains about 49 different proteins and 3 molecules of RNA
CC (25S, 5.8S and 5S). {ECO:0000255|HAMAP-Rule:MF_03122}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03122}.
CC Nucleus {ECO:0000255|HAMAP-Rule:MF_03122, ECO:0000269|PubMed:10564812}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS1 family.
CC {ECO:0000255|HAMAP-Rule:MF_03122}.
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DR EMBL; AF145757; AAF15410.1; -; mRNA.
DR EMBL; FR796431; CBZ12670.1; -; Genomic_DNA.
DR EMBL; FR796431; CBZ12671.1; -; Genomic_DNA.
DR EMBL; FR796431; CBZ12672.1; -; Genomic_DNA.
DR RefSeq; XP_003722437.1; XM_003722389.1.
DR RefSeq; XP_003722438.1; XM_003722390.1.
DR RefSeq; XP_003722439.1; XM_003722391.1.
DR AlphaFoldDB; Q4FX73; -.
DR SMR; Q4FX73; -.
DR STRING; 5664.LmjF.35.0400; -.
DR EnsemblProtists; CBZ12670; CBZ12670; LMJF_35_0400.
DR EnsemblProtists; CBZ12671; CBZ12671; LMJF_35_0410.
DR EnsemblProtists; CBZ12672; CBZ12672; LMJF_35_0420.
DR GeneID; 12982226; -.
DR GeneID; 12982227; -.
DR GeneID; 12982228; -.
DR KEGG; lma:LMJF_35_0400; -.
DR KEGG; lma:LMJF_35_0410; -.
DR KEGG; lma:LMJF_35_0420; -.
DR VEuPathDB; TriTrypDB:LmjF.35.0420; -.
DR VEuPathDB; TriTrypDB:LMJLV39_350009400; -.
DR VEuPathDB; TriTrypDB:LMJSD75_350009300; -.
DR eggNOG; KOG1628; Eukaryota.
DR InParanoid; Q4FX73; -.
DR OMA; GQNAYTK; -.
DR Proteomes; UP000000542; Chromosome 35.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:UniProtKB-UniRule.
DR GO; GO:0005654; C:nucleoplasm; ISO:GeneDB.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_03122; Ribosomal_S3Ae_euk; 1.
DR InterPro; IPR027500; Ribosomal_S1/3_euk.
DR InterPro; IPR001593; Ribosomal_S3Ae.
DR Pfam; PF01015; Ribosomal_S3Ae; 1.
DR SMART; SM01397; Ribosomal_S3Ae; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03122"
FT CHAIN 2..264
FT /note="40S ribosomal protein S3a"
FT /id="PRO_0000389347"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 115
FT /note="S -> N (in Ref. 1; AAF15410)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 264 AA; 30008 MW; 5E03B3B105DE7CC4 CRC64;
MALGKNKRIS KGGKRGKRGK AQETMARKEW YDVVAPANFE KRQFAKTICN KTQGTRIAAD
VLRGRVFEAN LADLNQSAGE EEAYRKVRFT VQEVQGRNLL TQFHSMEVTT DKMASLLRKW
CTTMETTVEV KTADGYTMRL FVVAFTKPQA NQQSRNCYAK QRLVKWLRMR ITKMIKRRLS
KVQIKEAVSL LTRNVLSDAL VRRCNPILPL RELRIRKVRV VRTPKFDAQA LLSAHGTIPA
SVEADQREVE EAVEAAPAAE KAAE
