ID   RS4A_SCHPO              Reviewed;         262 AA.
AC   P87158; O14378;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 2.
DT   03-AUG-2022, entry version 151.
DE   RecName: Full=40S ribosomal protein S4-A;
GN   Name=rps401; Synonyms=rps4, rps4a; ORFNames=SPBC19F8.08, SPBC25H2.17c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-81.
RC   STRAIN=972 / ATCC 24843;
RA   Jang Y.-J., Yoo H.-S.;
RL   Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC       {ECO:0000305}.
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DR   EMBL; CU329671; CAA19128.1; -; Genomic_DNA.
DR   EMBL; U97374; AAB63866.1; -; mRNA.
DR   PIR; T39831; T39831.
DR   PIR; T40012; T40012.
DR   RefSeq; NP_596350.1; NM_001022270.2.
DR   AlphaFoldDB; P87158; -.
DR   SMR; P87158; -.
DR   BioGRID; 277174; 60.
DR   STRING; 4896.SPBC19F8.08.1; -.
DR   iPTMnet; P87158; -.
DR   PaxDb; P87158; -.
DR   PRIDE; P87158; -.
DR   EnsemblFungi; SPBC19F8.08.1; SPBC19F8.08.1:pep; SPBC19F8.08.
DR   GeneID; 2540649; -.
DR   KEGG; spo:SPBC19F8.08; -.
DR   PomBase; SPBC19F8.08; rps401.
DR   VEuPathDB; FungiDB:SPBC19F8.08; -.
DR   eggNOG; KOG0378; Eukaryota.
DR   HOGENOM; CLU_060400_1_0_1; -.
DR   InParanoid; P87158; -.
DR   OMA; FPVGLMD; -.
DR   PhylomeDB; P87158; -.
DR   Reactome; R-SPO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-SPO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-SPO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-SPO-72649; Translation initiation complex formation.
DR   Reactome; R-SPO-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-SPO-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-SPO-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-SPO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-SPO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-SPO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P87158; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; ISO:PomBase.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:PomBase.
DR   GO; GO:0002181; P:cytoplasmic translation; ISO:PomBase.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd06087; KOW_RPS4; 1.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.740; -; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_00485; Ribosomal_S4e; 1.
DR   InterPro; IPR032277; 40S_S4_C.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041982; KOW_RPS4.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR000876; Ribosomal_S4e.
DR   InterPro; IPR013845; Ribosomal_S4e_central_region.
DR   InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR   InterPro; IPR013843; Ribosomal_S4e_N.
DR   InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11581; PTHR11581; 2.
DR   Pfam; PF16121; 40S_S4_C; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF00900; Ribosomal_S4e; 1.
DR   Pfam; PF08071; RS4NT; 1.
DR   Pfam; PF01479; S4; 1.
DR   PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   PROSITE; PS00528; RIBOSOMAL_S4E; 1.
DR   PROSITE; PS50889; S4; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..262
FT                   /note="40S ribosomal protein S4-A"
FT                   /id="PRO_0000130839"
FT   DOMAIN          42..105
FT                   /note="S4 RNA-binding"
FT   CONFLICT        9
FT                   /note="L -> F (in Ref. 2; AAB63866)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   262 AA;  29689 MW;  FBDCB5D1EB0537C1 CRC64;
     MVRGPKKHLK RVAAPHHWLL DKLSGTYAPK PSPGPHKARE CLPLIVFLRN RLKYALNGRE
     VKAILMQRLI KVDGKVRTDS TFPTGFMDVI SVEKTGEHFR LVYDIKGRFT VHRITAEEAK
     YKLCKVKRVQ LGAKGVPFLV THDGRTIRYP DPLIKVNDTI KLNLETNKIE SFIKFDTSAQ
     VMVTGGRNMG RVGTIVHREH HLGSFEIIHV KDALDREFAT RLSNVFVIGE TGKSWISLPK
     GKGVKLSITE ERDRRRALKG LA