ID   RS4E_PYRFU              Reviewed;         243 AA.
AC   Q8U011;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=30S ribosomal protein S4e {ECO:0000255|HAMAP-Rule:MF_00485};
DE   AltName: Full=Small ribosomal subunit protein eS4;
GN   Name=rps4e {ECO:0000255|HAMAP-Rule:MF_00485}; OrderedLocusNames=PF1812;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
RN   [2] {ECO:0007744|PDB:4V6U}
RP   STRUCTURE BY ELECTRON MICROSCOPY (6.60 ANGSTROMS) IN THE 70S RIBOSOME, AND
RP   SUBUNIT.
RX   PubMed=23222135; DOI=10.1093/nar/gks1259;
RA   Armache J.P., Anger A.M., Marquez V., Franckenberg S., Frohlich T.,
RA   Villa E., Berninghausen O., Thomm M., Arnold G.J., Beckmann R.,
RA   Wilson D.N.;
RT   "Promiscuous behaviour of archaeal ribosomal proteins: implications for
RT   eukaryotic ribosome evolution.";
RL   Nucleic Acids Res. 41:1284-1293(2013).
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit.
CC       {ECO:0000269|PubMed:23222135}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00485}.
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DR   EMBL; AE009950; AAL81936.1; -; Genomic_DNA.
DR   RefSeq; WP_011012953.1; NZ_CP023154.1.
DR   PDB; 4V6U; EM; 6.60 A; AE=1-243.
DR   PDB; 5JB3; EM; 5.34 A; E=1-243.
DR   PDB; 5JBH; EM; 5.34 A; E=1-243.
DR   PDBsum; 4V6U; -.
DR   PDBsum; 5JB3; -.
DR   PDBsum; 5JBH; -.
DR   AlphaFoldDB; Q8U011; -.
DR   SMR; Q8U011; -.
DR   STRING; 186497.PF1812; -.
DR   EnsemblBacteria; AAL81936; AAL81936; PF1812.
DR   GeneID; 41713631; -.
DR   KEGG; pfu:PF1812; -.
DR   PATRIC; fig|186497.12.peg.1883; -.
DR   eggNOG; arCOG04093; Archaea.
DR   HOGENOM; CLU_060400_0_0_2; -.
DR   OMA; FPVGLMD; -.
DR   OrthoDB; 89943at2157; -.
DR   PhylomeDB; Q8U011; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd06087; KOW_RPS4; 1.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.740; -; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_00485; Ribosomal_S4e; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041982; KOW_RPS4.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR000876; Ribosomal_S4e.
DR   InterPro; IPR013845; Ribosomal_S4e_central_region.
DR   InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR   InterPro; IPR013843; Ribosomal_S4e_N.
DR   InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11581; PTHR11581; 1.
DR   Pfam; PF00900; Ribosomal_S4e; 1.
DR   Pfam; PF08071; RS4NT; 1.
DR   Pfam; PF01479; S4; 1.
DR   PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR   SMART; SM00739; KOW; 1.
DR   SMART; SM00363; S4; 1.
DR   PROSITE; PS00528; RIBOSOMAL_S4E; 1.
DR   PROSITE; PS50889; S4; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding.
FT   CHAIN           1..243
FT                   /note="30S ribosomal protein S4e"
FT                   /id="PRO_0000130859"
FT   DOMAIN          43..105
FT                   /note="S4 RNA-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00485"
SQ   SEQUENCE   243 AA;  28146 MW;  0A0BF515902E1CE7 CRC64;
     MARKGPKRHL KRLAAPTSWY IERKAYKWAV RPRPGPHNMR TSIPLLYIVR DYLGYAKTAR
     EARKILNEGK FLVDGRVRKD YKFPVGIMDV VSIPETGEHY RVLPNRIGKL ILHPISEDEA
     FIKPLRIRNK RMIKGARVQL NFHDGTNHIV SIAEKDNYFT SYTVLMKVPE REILEVLPFE
     KGAYVFVTQG KNVARKGRIV EIKRFPMGWP DVVTIEDEEG ELFDTLKEYA FVVGTDKPKI
     SLP