ID   RS4X_DANRE              Reviewed;         263 AA.
AC   Q642H9;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=40S ribosomal protein S4, X isoform;
GN   Name=rps4x; Synonyms=rps4; ORFNames=zgc:92076;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC       {ECO:0000305}.
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DR   EMBL; BC081584; AAH81584.1; -; mRNA.
DR   RefSeq; NP_001005589.1; NM_001005589.1.
DR   AlphaFoldDB; Q642H9; -.
DR   SMR; Q642H9; -.
DR   STRING; 7955.ENSDARP00000108089; -.
DR   PaxDb; Q642H9; -.
DR   PRIDE; Q642H9; -.
DR   Ensembl; ENSDART00000128917; ENSDARP00000108089; ENSDARG00000014690.
DR   GeneID; 449547; -.
DR   KEGG; dre:449547; -.
DR   CTD; 6191; -.
DR   ZFIN; ZDB-GENE-040927-19; rps4x.
DR   eggNOG; KOG0378; Eukaryota.
DR   GeneTree; ENSGT00390000005569; -.
DR   HOGENOM; CLU_060400_1_0_1; -.
DR   InParanoid; Q642H9; -.
DR   OMA; FPVGLMD; -.
DR   OrthoDB; 1065966at2759; -.
DR   PhylomeDB; Q642H9; -.
DR   TreeFam; TF300612; -.
DR   Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DRE-72649; Translation initiation complex formation.
DR   Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DRE-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-DRE-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q642H9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 7.
DR   Bgee; ENSDARG00000014690; Expressed in tail bud paraxial mesoderm and 28 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0007420; P:brain development; IMP:ZFIN.
DR   GO; GO:0043009; P:chordate embryonic development; IMP:ZFIN.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd06087; KOW_RPS4; 1.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.740; -; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_00485; Ribosomal_S4e; 1.
DR   InterPro; IPR032277; 40S_S4_C.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041982; KOW_RPS4.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR000876; Ribosomal_S4e.
DR   InterPro; IPR013845; Ribosomal_S4e_central_region.
DR   InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR   InterPro; IPR013843; Ribosomal_S4e_N.
DR   InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11581; PTHR11581; 1.
DR   Pfam; PF16121; 40S_S4_C; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF00900; Ribosomal_S4e; 1.
DR   Pfam; PF08071; RS4NT; 1.
DR   Pfam; PF01479; S4; 1.
DR   PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   PROSITE; PS00528; RIBOSOMAL_S4E; 1.
DR   PROSITE; PS50889; S4; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..263
FT                   /note="40S ribosomal protein S4, X isoform"
FT                   /id="PRO_0000130824"
FT   DOMAIN          42..105
FT                   /note="S4 RNA-binding"
SQ   SEQUENCE   263 AA;  29688 MW;  6896BC99E0FC0AB6 CRC64;
     MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE
     VKKICMQRFI KIDGKVRTDI TYPTGFMDVV SIEKTGENFR LIYDVKGRFT VHRITNEEAK
     YKLCKVRKIL IGTKGIPHLV THDARTIRYP DPLIKVNDTI RIDLDTGKIT DFIKFETGNM
     CMVTGGANLG RIGVITNREK HPGSFDVVHV KDSIGNSFAT RLSNIFVIGK GNKPWVSLPR
     GKGVRLTIAE ERDKRLAAKQ SSS