RS4X_FELCA
ID RS4X_FELCA Reviewed; 263 AA.
AC P62705; P12631; P12750; P27576; P55831; Q14727;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=40S ribosomal protein S4, X isoform;
GN Name=RPS4X; Synonyms=RPS4;
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Thymic lymphoma;
RX PubMed=8607819; DOI=10.1006/bbrc.1996.0458;
RA Starkey C.R., Menon R.P., Prabhu S., Levy L.S.;
RT "Primary sequence and evolutionary conservation of ribosomal protein genes
RT from the domestic cat.";
RL Biochem. Biophys. Res. Commun. 220:648-652(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 20-213.
RC TISSUE=Blood;
RX PubMed=8808278; DOI=10.1006/geno.1996.0007;
RA Omoe K., Endo A.;
RT "Relationship between the monosomy X phenotype and Y-linked ribosomal
RT protein S4 (Rps4) in several species of mammals: a molecular evolutionary
RT analysis of Rps4 homologs.";
RL Genomics 31:44-50(1996).
CC -!- SUBUNIT: Identified in a IGF2BP1-dependent mRNP granule complex
CC containing untranslated mRNAs. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localized in
CC cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC {ECO:0000305}.
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DR EMBL; U22232; AAB01670.1; -; mRNA.
DR EMBL; D50106; BAA21077.1; -; mRNA.
DR PIR; PC4159; PC4159.
DR RefSeq; XP_004000676.1; XM_004000627.3.
DR AlphaFoldDB; P62705; -.
DR SMR; P62705; -.
DR IntAct; P62705; 1.
DR STRING; 9685.ENSFCAP00000011170; -.
DR PRIDE; P62705; -.
DR Ensembl; ENSFCAT00000012043; ENSFCAP00000011170; ENSFCAG00000024876.
DR GeneID; 768275; -.
DR KEGG; fca:768275; -.
DR CTD; 6191; -.
DR eggNOG; KOG0378; Eukaryota.
DR GeneTree; ENSGT00940000163191; -.
DR HOGENOM; CLU_060400_1_0_1; -.
DR InParanoid; P62705; -.
DR OMA; PARASIC; -.
DR OrthoDB; 1065966at2759; -.
DR Proteomes; UP000011712; Chromosome X.
DR Bgee; ENSFCAG00000024876; Expressed in embryonic head and 10 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; ISS:UniProtKB.
DR GO; GO:0005840; C:ribosome; ISS:UniProtKB.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd06087; KOW_RPS4; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 2.40.50.740; -; 1.
DR Gene3D; 3.10.290.10; -; 1.
DR HAMAP; MF_00485; Ribosomal_S4e; 1.
DR InterPro; IPR032277; 40S_S4_C.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR041982; KOW_RPS4.
DR InterPro; IPR014722; Rib_L2_dom2.
DR InterPro; IPR000876; Ribosomal_S4e.
DR InterPro; IPR013845; Ribosomal_S4e_central_region.
DR InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR InterPro; IPR013843; Ribosomal_S4e_N.
DR InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR PANTHER; PTHR11581; PTHR11581; 1.
DR Pfam; PF16121; 40S_S4_C; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF00900; Ribosomal_S4e; 1.
DR Pfam; PF08071; RS4NT; 1.
DR Pfam; PF01479; S4; 1.
DR PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR SMART; SM00363; S4; 1.
DR PROSITE; PS00528; RIBOSOMAL_S4E; 1.
DR PROSITE; PS50889; S4; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Cytoplasm; Isopeptide bond; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding;
KW Ubl conjugation.
FT CHAIN 1..263
FT /note="40S ribosomal protein S4, X isoform"
FT /id="PRO_0000130804"
FT DOMAIN 42..104
FT /note="S4 RNA-binding"
FT MOD_RES 233
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P62702"
FT CROSSLNK 230
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P62701"
SQ SEQUENCE 263 AA; 29598 MW; 87200E545A8958B0 CRC64;
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE
VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK
YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL
CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR
GKGIRLTIAE ERDKRLAAKQ SSG
