ID   BAMA_ECOK1              Reviewed;         810 AA.
AC   A1A7M1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE   Flags: Precursor;
GN   Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT;
GN   OrderedLocusNames=Ecok1_01670; ORFNames=APECO1_1810;
OS   Escherichia coli O1:K1 / APEC.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=405955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17293413; DOI=10.1128/jb.01726-06;
RA   Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA   Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT   "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT   shares strong similarities with human extraintestinal pathogenic E. coli
RT   genomes.";
RL   J. Bacteriol. 189:3228-3236(2007).
CC   -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC       involved in assembly and insertion of beta-barrel proteins into the
CC       outer membrane. Constitutes, with BamD, the core component of the
CC       assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC       membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC       {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
CC   -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
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DR   EMBL; CP000468; ABI99660.1; -; Genomic_DNA.
DR   RefSeq; WP_001240893.1; NC_008563.1.
DR   AlphaFoldDB; A1A7M1; -.
DR   BMRB; A1A7M1; -.
DR   SMR; A1A7M1; -.
DR   EnsemblBacteria; ABI99660; ABI99660; APECO1_1810.
DR   KEGG; ecv:APECO1_1810; -.
DR   HOGENOM; CLU_007664_1_0_6; -.
DR   OMA; IFMPAFG; -.
DR   Proteomes; UP000008216; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01430; OM_assembly_BamA; 1.
DR   InterPro; IPR000184; Bac_surfAg_D15.
DR   InterPro; IPR010827; BamA/TamA_POTRA.
DR   InterPro; IPR039910; D15-like.
DR   InterPro; IPR023707; OM_assembly_BamA.
DR   InterPro; IPR034746; POTRA.
DR   PANTHER; PTHR12815; PTHR12815; 1.
DR   PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR   Pfam; PF01103; Omp85; 1.
DR   Pfam; PF07244; POTRA; 4.
DR   PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR   TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR   PROSITE; PS51779; POTRA; 5.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Repeat; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT   CHAIN           21..810
FT                   /note="Outer membrane protein assembly factor BamA"
FT                   /id="PRO_1000024384"
FT   DOMAIN          24..91
FT                   /note="POTRA 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          92..172
FT                   /note="POTRA 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          175..263
FT                   /note="POTRA 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          266..344
FT                   /note="POTRA 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          347..421
FT                   /note="POTRA 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ   SEQUENCE   810 AA;  90622 MW;  DC8B4C9835A664EB CRC64;
     MAMKKLLIAS LLFSSATVYG AEGFVVKDIH FEGLQRVAVG AALLSMPVRT GDTVNDEDIS
     NTIRALFATG NFEDVRVLRD GDTLLVQVKE RPTIASITFS GNKSVKDDML KQNLEASGVR
     VGESLDRTTI ADIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFQ EGVSAEIQQI
     NIVGNHAFTT DELISHFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSYY LDRGYARFNI
     DSTQVSLTPD KKGIYVTVNI TEGDQYKLSG VEVSGNLAGH SAEIEQLTKI EPGELYNGTK
     VTKMEDDIKK LLGRYGYAYP RVQSMPEIND ADKTVKLRVN VDAGNRFYVR KIRFEGNDTS
     KDAVLRREMR QMEGAWLGSD LVDQGKERLN RLGFFETVDT DTQRVPGSPD QVDVVYKVKE
     RNTGSFNFGI GYGTESGVSF QAGVQQDNWL GTGYAVGING TKNDYQTYAE LSVTNPYFTV
     DGVSLGGRLF YNDFQADDAD LSDYTNKSYG TDVTLGFPIN EYNSLRAGLG YVHNSLSNMQ
     PQVAMWRYLY SMGEHPSTSD QDNSFKTDDF TFNYGWTYNK LDRGYFPTDG SRVNLTGKVT
     IPGSDNEYYK VTLDTATYVP IDDDHKWVVL GRTRWGYGDG LGGKEMPFYE NFYAGGSSTV
     RGFQSNTIGP KAVYFPHQAR NYDPDYDYEC ATQDGAKDLC KSDDAVGGNA MAVASLEFIT
     PTPFISDKYA NSVRTSFFWD MGTVWDTNWD SSQYSGYPDY SDPSNIRMSA GIALQWMSPL
     GPLVFSYAQP FKKYDGDKAE QFQFNIGKTW