ID   RS4_BOVIN               Reviewed;         263 AA.
AC   P79103; A5PJ76; Q3T0A5;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=40S ribosomal protein S4;
GN   Name=RPS4;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus, and Hereford; TISSUE=Hypothalamus, and Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 20-213.
RC   TISSUE=Blood;
RX   PubMed=8808278; DOI=10.1006/geno.1996.0007;
RA   Omoe K., Endo A.;
RT   "Relationship between the monosomy X phenotype and Y-linked ribosomal
RT   protein S4 (Rps4) in several species of mammals: a molecular evolutionary
RT   analysis of Rps4 homologs.";
RL   Genomics 31:44-50(1996).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC       {ECO:0000305}.
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DR   EMBL; BC102476; AAI02477.1; -; mRNA.
DR   EMBL; BC141995; AAI41996.1; -; mRNA.
DR   EMBL; D50107; BAA21078.1; -; mRNA.
DR   RefSeq; NP_001030522.1; NM_001035445.2.
DR   AlphaFoldDB; P79103; -.
DR   SMR; P79103; -.
DR   STRING; 9913.ENSBTAP00000025024; -.
DR   PaxDb; P79103; -.
DR   PeptideAtlas; P79103; -.
DR   PRIDE; P79103; -.
DR   Ensembl; ENSBTAT00000025024; ENSBTAP00000025024; ENSBTAG00000018800.
DR   GeneID; 614241; -.
DR   KEGG; bta:614241; -.
DR   CTD; 6191; -.
DR   VEuPathDB; HostDB:ENSBTAG00000018800; -.
DR   eggNOG; KOG0378; Eukaryota.
DR   GeneTree; ENSGT00390000005569; -.
DR   HOGENOM; CLU_060400_1_0_1; -.
DR   InParanoid; P79103; -.
DR   OMA; FPVGLMD; -.
DR   OrthoDB; 1065966at2759; -.
DR   TreeFam; TF300612; -.
DR   Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-BTA-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000009136; Chromosome X.
DR   Bgee; ENSBTAG00000018800; Expressed in adenohypophysis and 105 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd06087; KOW_RPS4; 1.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.740; -; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_00485; Ribosomal_S4e; 1.
DR   InterPro; IPR032277; 40S_S4_C.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041982; KOW_RPS4.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR000876; Ribosomal_S4e.
DR   InterPro; IPR013845; Ribosomal_S4e_central_region.
DR   InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR   InterPro; IPR013843; Ribosomal_S4e_N.
DR   InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11581; PTHR11581; 1.
DR   Pfam; PF16121; 40S_S4_C; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF00900; Ribosomal_S4e; 1.
DR   Pfam; PF08071; RS4NT; 1.
DR   Pfam; PF01479; S4; 1.
DR   PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   PROSITE; PS00528; RIBOSOMAL_S4E; 1.
DR   PROSITE; PS50889; S4; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..263
FT                   /note="40S ribosomal protein S4"
FT                   /id="PRO_0000130820"
FT   DOMAIN          42..104
FT                   /note="S4 RNA-binding"
FT   CONFLICT        80
FT                   /note="I -> V (in Ref. 2; BAA21078)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        95
FT                   /note="T -> I (in Ref. 2; BAA21078)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   263 AA;  29598 MW;  87200E545A8958B0 CRC64;
     MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE
     VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK
     YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL
     CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR
     GKGIRLTIAE ERDKRLAAKQ SSG