ID   RS4_CAEEL               Reviewed;         259 AA.
AC   Q9N3X2;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=40S ribosomal protein S4;
GN   Name=rps-4; ORFNames=Y43B11AR.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 11-48; 53-61; 81-99; 113-121; 134-144; 155-167;
RP   174-186; 191-229 AND 233-251, AND IDENTIFICATION BY MASS SPECTROMETRY.
RA   Bienvenut W.V.;
RL   Submitted (SEP-2005) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC       {ECO:0000255}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO081794; CCD74049.1; -; Genomic_DNA.
DR   RefSeq; NP_501103.1; NM_068702.4.
DR   AlphaFoldDB; Q9N3X2; -.
DR   SMR; Q9N3X2; -.
DR   BioGRID; 42600; 93.
DR   DIP; DIP-24988N; -.
DR   IntAct; Q9N3X2; 2.
DR   STRING; 6239.Y43B11AR.4; -.
DR   iPTMnet; Q9N3X2; -.
DR   EPD; Q9N3X2; -.
DR   PaxDb; Q9N3X2; -.
DR   PeptideAtlas; Q9N3X2; -.
DR   PRIDE; Q9N3X2; -.
DR   EnsemblMetazoa; Y43B11AR.4.1; Y43B11AR.4.1; WBGene00004473.
DR   GeneID; 177481; -.
DR   KEGG; cel:CELE_Y43B11AR.4; -.
DR   UCSC; Y43B11AR.4.1; c. elegans.
DR   CTD; 177481; -.
DR   WormBase; Y43B11AR.4; CE24278; WBGene00004473; rps-4.
DR   eggNOG; KOG0378; Eukaryota.
DR   GeneTree; ENSGT00390000005569; -.
DR   HOGENOM; CLU_060400_1_0_1; -.
DR   InParanoid; Q9N3X2; -.
DR   OMA; FPVGLMD; -.
DR   OrthoDB; 1065966at2759; -.
DR   PhylomeDB; Q9N3X2; -.
DR   Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-CEL-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-CEL-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q9N3X2; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00004473; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd06087; KOW_RPS4; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.740; -; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_00485; Ribosomal_S4e; 1.
DR   InterPro; IPR032277; 40S_S4_C.
DR   InterPro; IPR041982; KOW_RPS4.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR000876; Ribosomal_S4e.
DR   InterPro; IPR013845; Ribosomal_S4e_central_region.
DR   InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR   InterPro; IPR013843; Ribosomal_S4e_N.
DR   InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11581; PTHR11581; 1.
DR   Pfam; PF16121; 40S_S4_C; 1.
DR   Pfam; PF00900; Ribosomal_S4e; 1.
DR   Pfam; PF08071; RS4NT; 1.
DR   PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR   PROSITE; PS00528; RIBOSOMAL_S4E; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; RNA-binding; rRNA-binding.
FT   CHAIN           1..259
FT                   /note="40S ribosomal protein S4"
FT                   /id="PRO_0000130830"
FT   DOMAIN          41..100
FT                   /note="S4 RNA-binding"
SQ   SEQUENCE   259 AA;  29044 MW;  2A5CA98C640284E7 CRC64;
     MRGPKKHLKR LAAPSHWMLD KLGGVFAVRP NPGPHKLRES LPLSLFLRNR LKYALNYTEA
     KKILTQRVVR VDGKVRTCHK FPTGFMDVVA IERTNEYFRM LYDTKGRYVV HRIQAAEADF
     KLCKVKSVRT VNKGVPVLTT TDGRTIRYPD PHVKVNDTIV FNISTQKITD SVKFEPGNLA
     YVTGGRNVGR VGIIGHRERL PGASDIIHIK DSAGHSFATR ISNVFVIGKG NKALVSLPTG
     AGIRLSIAEE RDKRMAQKH