BAMA_HAEIN
ID BAMA_HAEIN Reviewed; 795 AA.
AC P44935;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE AltName: Full=80 kDa D15 antigen;
DE Short=D-15-Ag;
DE AltName: Full=Outer membrane protein D15;
DE AltName: Full=Protective surface antigen D15;
DE Flags: Precursor;
GN Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; OrderedLocusNames=HI_0917;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBUNIT: Part of the Bam complex. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
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DR EMBL; L42023; AAC22575.1; -; Genomic_DNA.
DR RefSeq; NP_439077.1; NC_000907.1.
DR RefSeq; WP_005693264.1; NC_000907.1.
DR PDB; 6J09; X-ray; 3.00 A; A=20-348.
DR PDBsum; 6J09; -.
DR AlphaFoldDB; P44935; -.
DR SMR; P44935; -.
DR STRING; 71421.HI_0917; -.
DR EnsemblBacteria; AAC22575; AAC22575; HI_0917.
DR KEGG; hin:HI_0917; -.
DR PATRIC; fig|71421.8.peg.958; -.
DR eggNOG; COG4775; Bacteria.
DR HOGENOM; CLU_007664_1_0_6; -.
DR OMA; IFMPAFG; -.
DR PhylomeDB; P44935; -.
DR BioCyc; HINF71421:G1GJ1-956-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:1990063; C:Bam protein complex; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IBA:GO_Central.
DR GO; GO:0051205; P:protein insertion into membrane; IBA:GO_Central.
DR HAMAP; MF_01430; OM_assembly_BamA; 1.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR010827; BamA/TamA_POTRA.
DR InterPro; IPR039910; D15-like.
DR InterPro; IPR023707; OM_assembly_BamA.
DR InterPro; IPR034746; POTRA.
DR PANTHER; PTHR12815; PTHR12815; 1.
DR PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR Pfam; PF01103; Omp85; 1.
DR Pfam; PF07244; POTRA; 4.
DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR PROSITE; PS51779; POTRA; 5.
PE 1: Evidence at protein level;
KW 3D-structure; Cell outer membrane; Membrane; Reference proteome; Repeat;
KW Signal; Transmembrane; Transmembrane beta strand.
FT SIGNAL 1..19
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT CHAIN 20..795
FT /note="Outer membrane protein assembly factor BamA"
FT /id="PRO_0000033468"
FT DOMAIN 22..89
FT /note="POTRA 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 90..170
FT /note="POTRA 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 173..259
FT /note="POTRA 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 262..341
FT /note="POTRA 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 344..418
FT /note="POTRA 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT HELIX 35..43
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 50..52
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 54..66
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 70..78
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 81..88
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 91..99
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 105..114
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 118..122
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 125..141
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 148..156
FT /evidence="ECO:0007829|PDB:6J09"
FT TURN 157..159
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 160..171
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 175..182
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 184..186
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 188..191
FT /evidence="ECO:0007829|PDB:6J09"
FT TURN 211..213
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 214..227
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 235..242
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 245..248
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 250..257
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 263..271
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 277..280
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 281..283
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 289..292
FT /evidence="ECO:0007829|PDB:6J09"
FT HELIX 295..311
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 318..322
FT /evidence="ECO:0007829|PDB:6J09"
FT TURN 327..330
FT /evidence="ECO:0007829|PDB:6J09"
FT STRAND 331..339
FT /evidence="ECO:0007829|PDB:6J09"
SQ SEQUENCE 795 AA; 87479 MW; B85691FC22E6ED44 CRC64;
MKKLLIASLL FGTTTTVFAA PFVAKDIRVD GVQGDLEQQI RASLPVRAGQ RVTDNDVANI
VRSLFVSGRF DDVKAHQEGD VLVVSVVAKS IISDVKIKGN SIIPTEALKQ NLDANGFKVG
DVLIREKLNE FAKSVKEHYA SVGRYNATVE PIVNTLPNNR AEILIQINED DKAKLASLTF
KGNESVSSST LQEQMELQPD SWWKLWGNKF EGAQFEKDLQ SIRDYYLNNG YAKAQITKTD
VQLNDEKTKV NVTIDVNEGL QYDLRSARII GNLGGMSAEL EPLLSALHLN DTFRRSDIAD
VENAIKAKLG ERGYGSATVN SVPDFDDANK TLAITLVVDA GRRLTVRQLR FEGNTVSADS
TLRQEMRQQE GTWYNSQLVE LGKIRLDRTG FFETVENRID PINGSNDEVD VVYKVKERNT
GSINFGIGYG TESGISYQAS VKQDNFLGTG AAVSIAGTKN DYGTSVNLGY TEPYFTKDGV
SLGGNVFFEN YDNSKSDTSS NYKRTTYGSN VTLGFPVNEN NSYYVGLGHT YNKISNFALE
YNRNLYIQSM KFKGNGIKTN DFDFSFGWNY NSLNRGYFPT KGVKASLGGR VTIPGSDNKY
YKLSADVQGF YPLDRDHLWV VSAKASAGYA NGFGNKRLPF YQTYTAGGIG SLRGFAYGSI
GPNAIYAEHG NGNGTFKKIS SDVIGGNAIT TASAELIVPT PFVSDKSQNT VRTSLFVDAA
SVWNTKWKSD KSGLDNNVLK SLPDYGKSSR IRASTGVGFQ WQSPIGPLVF SYAKPIKKYE
NDDVEQFQFS IGGSF
